Reviewed,
UniProtKB/Swiss-Prot Q5V4R0 (DNLI_HALMA)
Last modified
November 25, 2008.
Version 34.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: DNA ligase EC=6.5.1.1 Alternative name(s): Polydeoxyribonucleotide synthase [ATP] | ||||
| Gene names |
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| Organism | Haloarcula marismortui (Halobacterium marismortui) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 2238 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloarcula |
Protein attributes
| Sequence length | 554 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | This protein seals, during DNA replication, DNA recombination and DNA repair, nicks in double-stranded DNA By similarity. |
| Catalytic activity | ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). |
| Sequence similarities | Belongs to the ATP-dependent DNA ligase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Cell cycle Cell division DNA damage DNA recombination DNA repair DNA replication |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Ligase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | DNA recombination Inferred from electronic annotation. Source: HAMAP DNA repairInferred from electronic annotation. Source: HAMAP DNA replicationInferred from electronic annotation. Source: HAMAP cell cycleInferred from electronic annotation. Source: UniProtKB-KW cell divisionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | ATP binding Inferred from electronic annotation. Source: HAMAP DNA bindingInferred from electronic annotation. Source: InterPro DNA ligase (ATP) activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea." Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V. Genome Res. 14:2221-2234(2004) [PubMed: 15520287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43049 / DSM 3752 / JCM 8966. |
Cross-references
Sequence databases | |
|---|---|
| AY596297 Genomic DNA. Translation: AAV45492.1. | |
| RefSeq | YP_135198.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3130622. |
| GenomeReviews | Gene locus rrnAC0463 in contig AY596297_GR. |
| KEGG | hma:rrnAC0463. |
| NMPDR | fig|272569.1.peg.457. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q5V4R0. |
Enzyme and pathway databases | |
| BioCyc | HMAR272569:RRNAC0463-MON. |
Family and domain databases | |
| HAMAP | MF_00407. [Tree] |
| InterPro | IPR000977. DNA_ligase. IPR012309. DNA_ligase_A_C. IPR012310. DNA_ligase_A_M. IPR012308. DNA_ligase_A_N. IPR016059. DNA_ligase_CS. IPR012340. NA-bd_OB-fold. [Graphical view] |
| Gene3D | G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit. |
| Pfam | PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00574. dnl1. 1 hit. |
| PROSITE | PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. False negative. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DNLI_HALMA | ||||||||
| Accession | Primary (citable) accession number: Q5V4R0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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