ID   Q5V3F7_HALMA            Unreviewed;       630 AA.
AC   Q5V3F7;
DT   07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT   07-DEC-2004, sequence version 1.
DT   27-MAR-2024, entry version 97.
DE   SubName: Full=MCP domain signal transducer {ECO:0000313|EMBL:AAV45945.1};
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:QCP90716.1};
GN   Name=htr8 {ECO:0000313|EMBL:AAV45945.1};
GN   OrderedLocusNames=rrnAC0976 {ECO:0000313|EMBL:AAV45945.1};
GN   ORFNames=E6P14_07505 {ECO:0000313|EMBL:QCP90716.1};
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569 {ECO:0000313|EMBL:AAV45945.1, ECO:0000313|Proteomes:UP000001169};
RN   [1] {ECO:0000313|EMBL:AAV45945.1, ECO:0000313|Proteomes:UP000001169}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 {ECO:0000313|EMBL:AAV45945.1}, and ATCC 43049 / DSM
RC   3752 / JCM 8966 / VKM B-1809 {ECO:0000313|Proteomes:UP000001169};
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
RN   [2] {ECO:0000313|EMBL:QCP90716.1, ECO:0000313|Proteomes:UP000298722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 {ECO:0000313|EMBL:QCP90716.1,
RC   ECO:0000313|Proteomes:UP000298722};
RA   DasSarma S., DasSarma P., DasSarma S., Fomenkov A., Vincze T., Anton B.P.,
RA   Roberts R.J.;
RT   "Methylomes of two halophilic Archaea, Haloarcula marismortui and Haloferax
RT   mediterranei.";
RL   Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AY596297; AAV45945.1; -; Genomic_DNA.
DR   EMBL; CP039138; QCP90716.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5V3F7; -.
DR   STRING; 272569.rrnAC0976; -.
DR   PaxDb; 272569-rrnAC0976; -.
DR   EnsemblBacteria; AAV45945; AAV45945; rrnAC0976.
DR   KEGG; hma:rrnAC0976; -.
DR   PATRIC; fig|272569.17.peg.1706; -.
DR   eggNOG; arCOG02320; Archaea.
DR   HOGENOM; CLU_000445_107_18_2; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   Proteomes; UP000298722; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001169};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        149..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          274..320
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          339..577
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          217..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          241..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        241..258
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   630 AA;  67963 MW;  7C87CFB372269061 CRC64;
     MAQPTGDIGQ QTDRNPGPVE RLESFVSYIP DGSTIPDKQW RNRHRSVVVV TLLHIPFLFG
     LGIYTGSTPI AEAQIPATAL PRVLLLCGVV FALSAGSLIA RFRRRVRTIL SVTAVFVSSL
     ALVQLSGGYI EAHFHFFVGM AMVAVYEDWV PFLWGLAYVV LTHGYFGTID PSRVYNHAAA
     INNPWAWGLI HGGFVLMLCV ALVNNWVSTE RSREKSQERF EQAEQRASEI DDLQAKQEEI
     ERKRAEAKEA REKAEAKMQA AEQQNTELQE TASRFSEAMA AAADGDLTVR VDPDVADNEA
     MAQIAESFNK MMTETESAME EIQTFSEEVA TTSDQVTAGA NEATGASEDM SESIQGIASG
     ADEQREMLET VSDEMTDLSA TVEEVAASAE TVAERSRETA EIADAGQETA QEAIAGSREV
     QTAIDSTVEN VERLDEKMAE IGDIVELIGD IAEQTNMLAL NANIEAARAG NGSGGDGFAV
     VADEVKQLAE ETQTSASEIE QLIAETQAQT ETTVTEARGA KEDMQESTEA VEAVVDTFTQ
     VAENAEATDN GIQEISDTTD DQAATTEETV AMVEEAVDIS EATAAETETA SATAEEQAAS
     MSQVSASIES LADQSERLQT MLSEFEVGSR
//