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Reviewed, UniProtKB/Swiss-Prot Q5V311 (F16A2_HALMA)

Last modified September 22, 2009. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Fructose-1,6-bisphosphatase class 1 2
      Short name=FBPase class 1 2
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2
Gene names
Name: fbp2
Ordered Locus Names: rrnAC1138
OrganismHaloarcula marismortui (Halobacterium marismortui) [Complete proteome] [HAMAP]
Taxonomic identifier2238 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloarcula

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Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the FBPase class 1 family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 282282Fructose-1,6-bisphosphatase class 1 2 HAMAP MF_01855
PRO_0000364769

Regions

Region86 – 894Substrate binding By similarity

Sites

Metal binding661Magnesium 1 By similarity
Metal binding831Magnesium 1 By similarity
Metal binding831Magnesium 2 By similarity
Metal binding851Magnesium 1; via carbonyl oxygen By similarity
Metal binding861Magnesium 2 By similarity
Metal binding2281Magnesium 2 By similarity
Binding site1921Substrate By similarity
Binding site2221Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q5V311-1 [UniParc].

Last modified March 3, 2009. Version 2.
Checksum: DFD940FF909E02ED

FASTA28229,980
        10         20         30         40         50         60 
MNTLDEIERA VKDTAHYVSG NLANYANRAA GENPSGEQQV GGDVWADDLF FDALAYIDGI 

        70         80         90        100        110        120 
GAYASEERSD VVDCGEGYSI AIDPLDGSSN LASNNSVGTI IGVYDAELPA AGREMVASLM 

       130        140        150        160        170        180 
VLYGPYTTLT IARSDRDVVQ EHLLRDGHSE RWGQFELPAE ATVVGLAGKT GERSDAFNDI 

       190        200        210        220        230        240 
AQSFERDLKL RYGGATVADL AQVLEYGGLF GYPVTSGYPN GKLRVHFESA PLAYLVEAAG 

       250        260        270        280 
GASSDGSQSL LDVEPDGIHD RTPTFLGNAE LVDELEAALS ET

« Hide

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References

[1]"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea."
Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V.
Genome Res. 14:2221-2234(2004) [PubMed: 15520287] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43049 / DSM 3752 / JCM 8966.

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Cross-references

Sequence databases

AY596297 Genomic DNA. Translation: AAV46091.1. Different initiation.
RefSeqYP_135797.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3129206.
GenomeReviewsGene locus rrnAC1138 in contig AY596297_GR.
KEGGhma:rrnAC1138.

Organism-specific databases

CMRSearch...

Enzyme and pathway databases

BioCycHMAR272569:RRNAC1138-MON.

Family and domain databases

HAMAPMF_01855.
[Tree]
InterProIPR000146. Fructose_bisphosphatase.
IPR020548. Fructose_bisphosphatase_AS.
[Graphical view]
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. False negative.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameF16A2_HALMA
AccessionPrimary (citable) accession number: Q5V311
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 3, 2009
Last modified: September 22, 2009
This is version 32 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents