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Q5V214 (TRPG1_HALMA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Anthranilate synthase component II

EC=4.1.3.27
Gene names
Name:trpG1
Ordered Locus Names:rrnAC1517
OrganismHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) [Complete proteome] [HAMAP]
Taxonomic identifier272569 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula

Protein attributes

Sequence length207 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.

Subunit structure

Tetramer of two components I and two components II By similarity.

Miscellaneous

Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity.

Sequence similarities

Contains 1 glutamine amidotransferase type-1 domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 207207Anthranilate synthase component II
PRO_0000056880

Regions

Domain17 – 207191Glutamine amidotransferase type-1

Sites

Active site961 By similarity
Active site1871 By similarity
Active site1891 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5V214 [UniParc].

Last modified December 7, 2004. Version 1.
Checksum: C9DBC7C50BD983B7

FASTA20722,292
        10         20         30         40         50         60 
MSTAQPAGAD AVRDDLRVLF VDNFDSFTYN LVEYVSEHAE TEVVRNTASL DDVEAFDPDA 

        70         80         90        100        110        120 
IILSPGPGHP KNERDVGVTL DVLREVSPDV PTLGVCLGLE SAVYAYGGTI GRAPEPIHGK 

       130        140        150        160        170        180 
AFPIDHDGKG VFAGLEQGFQ GGRYHSLIAD DVPEEFVVSA TTETEDGTEL VMGVRHREHP 

       190        200 
IEAVQFHPES VLTAVGHDVI RNFLAGL 

« Hide

References

[1]"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea."
Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V.
Genome Res. 14:2221-2234(2004) [PubMed: 15520287] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY596297 Genomic DNA. Translation: AAV46438.1.
RefSeqYP_136144.1. NC_006396.1.

3D structure databases

ProteinModelPortalQ5V214.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3127597.
GenomeReviewsGene locus rrnAC1517 in contig AY596297_GR.
KEGGhma:rrnAC1517.
NMPDRfig|272569.1.peg.1408.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG292341.
OMAREHPIEA.
PhylomeDBQ5V214.
ProtClustDBCLSK511483.

Enzyme and pathway databases

BioCycHMAR272569:RRNAC1517-MONOMER.

Family and domain databases

InterProIPR017926. GATASE_1.
IPR006221. TrpG_papA.
[Graphical view]
KOK01658.
PfamPF00117. GATase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00566. TrpG_papA. 1 hit.
PROSITEPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRPG1_HALMA
AccessionPrimary (citable) accession number: Q5V214
Entry history
Integrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: December 7, 2004
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families