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Protein

Probable L-aspartate decarboxylase

Gene

mfnA

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.UniRule annotation

Catalytic activityi

L-aspartate = beta-alanine + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Pathwayi: coenzyme A biosynthesis

This protein is involved in the pathway coenzyme A biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway coenzyme A biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylase, Lyase
LigandPyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00241

Names & Taxonomyi

Protein namesi
Recommended name:
Probable L-aspartate decarboxylaseUniRule annotation (EC:4.1.1.11UniRule annotation)
Short name:
ADCUniRule annotation
Gene namesi
Name:mfnAUniRule annotation
Ordered Locus Names:rrnAC1798
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHaloarculaceaeHaloarcula
Proteomesi
  • UP000001169 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001470201 – 350Probable L-aspartate decarboxylaseAdd BLAST350

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei206N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi272569.rrnAC1798

Structurei

3D structure databases

ProteinModelPortaliQ5V1B4
SMRiQ5V1B4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family. MfnA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00027 Archaea
COG0076 LUCA
HOGENOMiHOG000246269
KOiK18933
OMAiDPHKMGL
OrthoDBiPOG093Z06IK

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
HAMAPiMF_01610 MfnA_decarbox, 1 hit
InterProiView protein in InterPro
IPR020931 MfnA
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR03812 tyr_de_CO2_Arch, 1 hit

Sequencei

Sequence statusi: Complete.

Q5V1B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQRAEPQDF ERVLSSMCTV PHPSAREAAE RFLATNPGDP GTYETIAGLE
60 70 80 90 100
REAVEYLGDI TGLSDPAGYV ASGGTEANLQ AIRIARNRAD TDDPNVVAPV
110 120 130 140 150
HAHFSFTKAA DVLGVELRTA PAADYRVNMA AMAELVDEDT VCVVGVAGST
160 170 180 190 200
EYGYVDPIPA IADLAETVDA LCHVDAAWGG FYLPFTDHDW HFGHADIDTM
210 220 230 240 250
TIDPHKVGQA AVPAGGLLAR DRTLLDELAV ETPYLESTDQ LTLTGTRSGA
260 270 280 290 300
GVASAVAAME SLWPAGYRQQ YETSMANADW LADQLSARGH DVVGPELPLV
310 320 330 340 350
AADLSMPMTD ELRDRGWRVS KTGAGEMRVV CMPHVTRSML RSFVADLDWY
Length:350
Mass (Da):37,666
Last modified:December 7, 2004 - v1
Checksum:i63B2A9E21FF87177
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY596297 Genomic DNA Translation: AAV46689.1
RefSeqiWP_007188823.1, NC_006396.1

Genome annotation databases

EnsemblBacteriaiAAV46689; AAV46689; rrnAC1798
GeneIDi3128786
KEGGihma:rrnAC1798
PATRICifig|272569.17.peg.2470

Similar proteinsi

Entry informationi

Entry nameiMFNA_HALMA
AccessioniPrimary (citable) accession number: Q5V1B4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: December 7, 2004
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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