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Protein

DNA-directed RNA polymerase subunit A''

Gene

rpoA2

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciHMAR272569:GJDH-2189-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit A''UniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:rpoA2UniRule annotation
Ordered Locus Names:rrnAC2427
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula
Proteomesi
  • UP000001169 Componenti: Chromosome I

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 395395DNA-directed RNA polymerase subunit A''PRO_1000080473Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272569.rrnAC2427.

Structurei

3D structure databases

ProteinModelPortaliQ5UZR5.
SMRiQ5UZR5. Positions 61-108.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
KOiK03042.
OMAiRPIGRHG.

Family and domain databases

HAMAPiMF_00411. RNApol_arch_A.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5UZR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAHDVSADI EAVVEDTELP RRLKDEVYST IEERGVGVDD ADRIAKAVET
60 70 80 90 100
RYLDTRVDPL DPVGTVSAQS IGEPGTQMTM NTFHYAGVAE IDVTQGLPRL
110 120 130 140 150
IELVDARKTP DTPMMTVHLD EEYATDRERA HEVVWKIEAT RILALGDIST
160 170 180 190 200
NVADMLVEID LNEDTLLERW PTVNDTDAIA EEIAETIESN LGVSTRQAGT
210 220 230 240 250
LIEFGPEEPS YRDLLQLVEE LREIVFKGIE EITRVVIRKE ETDNGEEFVL
260 270 280 290 300
YTEGSDFGEV LDIEGVDASR TTCNNIHEIY RELGVEAARE TLINETMNTL
310 320 330 340 350
EEQGLDDVNV RHLMLVADIM TNEGTIESIG RHGISGSKDS VLARAAFEVT
360 370 380 390
VNHLLDAAIH GEVDELDGVT ENVIVGKPIK LGTGDVNLRM GTTQD
Length:395
Mass (Da):43,671
Last modified:December 7, 2004 - v1
Checksum:iECF4966E834AAD6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY596297 Genomic DNA. Translation: AAV47238.1.
RefSeqiWP_005537132.1. NC_006396.1.

Genome annotation databases

EnsemblBacteriaiAAV47238; AAV47238; rrnAC2427.
GeneIDi3130049.
KEGGihma:rrnAC2427.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY596297 Genomic DNA. Translation: AAV47238.1.
RefSeqiWP_005537132.1. NC_006396.1.

3D structure databases

ProteinModelPortaliQ5UZR5.
SMRiQ5UZR5. Positions 61-108.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272569.rrnAC2427.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV47238; AAV47238; rrnAC2427.
GeneIDi3130049.
KEGGihma:rrnAC2427.

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
KOiK03042.
OMAiRPIGRHG.

Enzyme and pathway databases

BioCyciHMAR272569:GJDH-2189-MONOMER.

Family and domain databases

HAMAPiMF_00411. RNApol_arch_A.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.

Entry informationi

Entry nameiRPOA2_HALMA
AccessioniPrimary (citable) accession number: Q5UZR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 7, 2004
Last modified: November 11, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.