ID   Q5UZK4_HALMA            Unreviewed;       566 AA.
AC   Q5UZK4;
DT   07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT   07-DEC-2004, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   SubName: Full=MCP domain signal transducer {ECO:0000313|EMBL:AAV47299.1};
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:QCP92005.1};
GN   Name=htr14 {ECO:0000313|EMBL:AAV47299.1};
GN   OrderedLocusNames=rrnAC2495 {ECO:0000313|EMBL:AAV47299.1};
GN   ORFNames=E6P14_14500 {ECO:0000313|EMBL:QCP92005.1};
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569 {ECO:0000313|EMBL:AAV47299.1, ECO:0000313|Proteomes:UP000001169};
RN   [1] {ECO:0000313|EMBL:AAV47299.1, ECO:0000313|Proteomes:UP000001169}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 {ECO:0000313|EMBL:AAV47299.1}, and ATCC 43049 / DSM
RC   3752 / JCM 8966 / VKM B-1809 {ECO:0000313|Proteomes:UP000001169};
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
RN   [2] {ECO:0000313|EMBL:QCP92005.1, ECO:0000313|Proteomes:UP000298722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 {ECO:0000313|EMBL:QCP92005.1,
RC   ECO:0000313|Proteomes:UP000298722};
RA   DasSarma S., DasSarma P., DasSarma S., Fomenkov A., Vincze T., Anton B.P.,
RA   Roberts R.J.;
RT   "Methylomes of two halophilic Archaea, Haloarcula marismortui and Haloferax
RT   mediterranei.";
RL   Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AY596297; AAV47299.1; -; Genomic_DNA.
DR   EMBL; CP039138; QCP92005.1; -; Genomic_DNA.
DR   RefSeq; WP_011224261.1; NZ_CP039138.1.
DR   AlphaFoldDB; Q5UZK4; -.
DR   STRING; 272569.rrnAC2495; -.
DR   PaxDb; 272569-rrnAC2495; -.
DR   EnsemblBacteria; AAV47299; AAV47299; rrnAC2495.
DR   GeneID; 40153390; -.
DR   KEGG; hma:rrnAC2495; -.
DR   PATRIC; fig|272569.17.peg.3105; -.
DR   eggNOG; arCOG02320; Archaea.
DR   HOGENOM; CLU_000445_107_18_2; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   Proteomes; UP000298722; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 3.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 2.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001169};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        30..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          80..133
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          260..496
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          303..358
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   566 AA;  59942 MW;  BE220B810B797C48 CRC64;
     MLTDPIRKYK AVIRGSLDVF GVSGSVERKV LAAVGLQFGA SVALAVVSLV ATGTVRFVVT
     GVLLAGAIVA FANTVFITRE DFVEPVTAMA AGADHIASGE LDVELPESER DDEVAELLSS
     FRSMQSYLLT VSRQADALSR QEFDADVLDE DVPGTFGQSL EQMAASMDEY TTELQTMTSD
     LERRSQALND LVVAFGDAAE QAKDGDLTAT IDEEFAADDE QFDAVVENYN DLVTTLGETV
     ATVAAFAEDV DETSDHVTRS VTEINDASDE ISRSIQEISA GASQQASRHD DVASEMNTLS
     ATVEEIAATA ENAADTAEKA TRRGREGRAD AEQAIDELDE MEARIDDIAV AVESLVDQIS
     EIDDIVEVIT DIAEQTNMLA LNASIEAARA DGSGDGFAVV ADEVKTLAEE THDAATDVSD
     RIEAVQHEAS ETVSNVEATN QQVTDSAATI ESALRDFEDI VDVLGEVNAS IQEISGATAE
     QAETTQEVVD MVDEVAAVSE QTNEESEAVA AATEEQTATI TEVTTEVQEM AAQTDDLREV
     LAAFDIAEGA GPSKTVSTAT VTTADD
//