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Q5UZD7 (RPIA_HALMA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribose-5-phosphate isomerase A

EC=5.3.1.6
Alternative name(s):
Phosphoriboisomerase A
Short name=PRI
Gene names
Name:rpiA
Ordered Locus Names:rrnAC2572
OrganismHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) [Complete proteome] [HAMAP]
Taxonomic identifier272569 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula

Protein attributes

Sequence length228 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate By similarity. HAMAP-Rule MF_00170

Catalytic activity

D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP-Rule MF_00170

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP-Rule MF_00170

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00170

Sequence similarities

Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpentose-phosphate shunt, non-oxidative branch

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribose-5-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 228228Ribose-5-phosphate isomerase A HAMAP-Rule MF_00170
PRO_0000158507

Regions

Region31 – 344Substrate binding By similarity
Region85 – 884Substrate binding By similarity
Region97 – 1004Substrate binding By similarity

Sites

Active site1061Proton acceptor By similarity
Binding site1241Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5UZD7 [UniParc].

Last modified December 7, 2004. Version 1.
Checksum: 87BD40081AE76DD2

FASTA22823,080
        10         20         30         40         50         60 
MKQGGSDAAK QAAGESAAEA VEDATVVGLG TGSTAAYAIR AIGQAVDAGL DVVGVPTSFQ 

        70         80         90        100        110        120 
SRQLARDCGI PLADLDDVSV DLAIDGADEV ASGNLIKGGG AAHAREKIVD ASADRFLVVA 

       130        140        150        160        170        180 
DPTKEAAVLS YPVPVEVLPM ARSTVVTAVE ELGGDPTLRR AERKDGPVVT DNGNLVLDCD 

       190        200        210        220 
FNSIHDPAAL ASDLAALPGV VEHGLFVGMA DEIHVGTADG VTVRTLSK 

« Hide

References

[1]"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea."
Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V.
Genome Res. 14:2221-2234(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY596297 Genomic DNA. Translation: AAV47366.1.
RefSeqYP_137072.1. NC_006396.1.

3D structure databases

ProteinModelPortalQ5UZD7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272569.rrnAC2572.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAV47366; AAV47366; rrnAC2572.
GeneID3129505.
KEGGhma:rrnAC2572.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0120.
HOGENOMHOG000276369.
KOK01807.
OMAGACHVQE.
ProtClustDBPRK00702.

Enzyme and pathway databases

BioCycHMAR272569:GJDH-2322-MONOMER.
UniPathwayUPA00115; UER00412.

Family and domain databases

HAMAPMF_00170. Rib_5P_isom_A.
InterProIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERPTHR11934. PTHR11934. 1 hit.
PfamPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsTIGR00021. rpiA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPIA_HALMA
AccessionPrimary (citable) accession number: Q5UZD7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: December 7, 2004
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways