Q5UZD7 (RPIA_HALMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	rrnAC2572

Organism

Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) [Complete proteome] [HAMAP]

Taxonomic identifier

272569 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloarcula › Haloarcula marismortui

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP-Rule MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP-Rule MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	Ribose-5-phosphate isomerase A HAMAP-Rule MF_00170		PRO_0000158507

Sequences

	Sequence		Length	Mass (Da)
	Q5UZD7 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: 87BD40081AE76DD2	FASTA	228	23,080
	10 20 30 40 50 60 MKQGGSDAAK QAAGESAAEA VEDATVVGLG TGSTAAYAIR AIGQAVDAGL DVVGVPTSFQ 70 80 90 100 110 120 SRQLARDCGI PLADLDDVSV DLAIDGADEV ASGNLIKGGG AAHAREKIVD ASADRFLVVA 130 140 150 160 170 180 DPTKEAAVLS YPVPVEVLPM ARSTVVTAVE ELGGDPTLRR AERKDGPVVT DNGNLVLDCD 190 200 210 220 FNSIHDPAAL ASDLAALPGV VEHGLFVGMA DEIHVGTADG VTVRTLSK

References

[1]

"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea." Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V. Genome Res. 14:2221-2234(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY596297 Genomic DNA. Translation: AAV47366.1.
RefSeq	YP_137072.1. NC_006396.1.
3D structure databases
ProteinModelPortal	Q5UZD7.
ModBase	Search...
Protein-protein interaction databases
STRING	272569.rrnAC2572.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAV47366; AAV47366; rrnAC2572.
GeneID	3129505.
KEGG	hma:rrnAC2572.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0120.
HOGENOM	HOG000276369.
KO	K01807.
OMA	STTAYFI.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	HMAR272569:GJDH-2322-MONOMER.
UniPathway	UPA00115; UER00412.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A.
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
PANTHER	PTHR11934. PTHR11934. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. rpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_HALMA

Accession

Primary (citable) accession number: Q5UZD7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	December 7, 2004
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program