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Q5UXU0

- G6PI_HALMA

UniProt

Q5UXU0 - G6PI_HALMA

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Protein
Probable glucose-6-phosphate isomerase
Gene
pgi, rrnAC3210
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei272 – 2721Proton donor By similarity
Active sitei293 – 2931 By similarity
Active sitei404 – 4041 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciHMAR272569:GJDH-2882-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:rrnAC3210
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula
ProteomesiUP000001169: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 436436Probable glucose-6-phosphate isomeraseUniRule annotation
PRO_0000180778Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272569.rrnAC3210.

Structurei

3D structure databases

ProteinModelPortaliQ5UXU0.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100402.
KOiK01810.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5UXU0-1 [UniParc]FASTAAdd to Basket

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MHVDIGAALA SAADPGVERA TLDDLDEQVA VAHERIEQGR NKGEFGYASL    50
NLLEATDAET IHDAVAPVAD AESVITVGIG GSALGAKTIT EALAEDPGSH 100
VVLDNVDPEH VRRTLDGLSL ADTAINVVSR SGTTAETLAN FLVVREAYED 150
RGVDWTERIV VTTGESGPLR ALADQHDLPT LPVPEGVPGR FSALSAVGLV 200
PPAILGIDIE GLLAGGQQAA DDLAPSLYDS PAYAYGAMAY ALEEAGATVN 250
AVMPYAERLE SFGEWFAQLW AESLGKDGRG QTPARALGAT DQHSQLQLYR 300
AGHRDKVVTF VRPRERADVS IPDPDHEDLS YLAGTDLGGL IDAEYEATVA 350
SLPAADRPAL EVEIDRLDAE SVGELLYAME AACVLVGELA DVETFTQPAV 400
EWGKNATRAL IRGEATDETA VIDERERLRI GETESL 436
Length:436
Mass (Da):46,180
Last modified:November 8, 2005 - v2
Checksum:i94D7F534A87BAB18
GO

Sequence cautioni

The sequence AAV47913.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY596297 Genomic DNA. Translation: AAV47913.1. Different initiation.
RefSeqiYP_137619.1. NC_006396.1.

Genome annotation databases

EnsemblBacteriaiAAV47913; AAV47913; rrnAC3210.
GeneIDi3129274.
KEGGihma:rrnAC3210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY596297 Genomic DNA. Translation: AAV47913.1 . Different initiation.
RefSeqi YP_137619.1. NC_006396.1.

3D structure databases

ProteinModelPortali Q5UXU0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272569.rrnAC3210.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAV47913 ; AAV47913 ; rrnAC3210 .
GeneIDi 3129274.
KEGGi hma:rrnAC3210.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100402.
KOi K01810.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci HMAR272569:GJDH-2882-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.

Entry informationi

Entry nameiG6PI_HALMA
AccessioniPrimary (citable) accession number: Q5UXU0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: June 11, 2014
This is version 53 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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