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Q5UXU0

- G6PI_HALMA

UniProt

Q5UXU0 - G6PI_HALMA

Protein

Probable glucose-6-phosphate isomerase

Gene

pgi

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 2 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei272 – 2721Proton donorUniRule annotation
    Active sitei293 – 2931UniRule annotation
    Active sitei404 – 4041UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciHMAR272569:GJDH-2882-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:rrnAC3210
    OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
    Taxonomic identifieri272569 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula
    ProteomesiUP000001169: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 436436Probable glucose-6-phosphate isomerasePRO_0000180778Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272569.rrnAC3210.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5UXU0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100402.
    KOiK01810.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5UXU0-1 [UniParc]FASTAAdd to Basket

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    MHVDIGAALA SAADPGVERA TLDDLDEQVA VAHERIEQGR NKGEFGYASL    50
    NLLEATDAET IHDAVAPVAD AESVITVGIG GSALGAKTIT EALAEDPGSH 100
    VVLDNVDPEH VRRTLDGLSL ADTAINVVSR SGTTAETLAN FLVVREAYED 150
    RGVDWTERIV VTTGESGPLR ALADQHDLPT LPVPEGVPGR FSALSAVGLV 200
    PPAILGIDIE GLLAGGQQAA DDLAPSLYDS PAYAYGAMAY ALEEAGATVN 250
    AVMPYAERLE SFGEWFAQLW AESLGKDGRG QTPARALGAT DQHSQLQLYR 300
    AGHRDKVVTF VRPRERADVS IPDPDHEDLS YLAGTDLGGL IDAEYEATVA 350
    SLPAADRPAL EVEIDRLDAE SVGELLYAME AACVLVGELA DVETFTQPAV 400
    EWGKNATRAL IRGEATDETA VIDERERLRI GETESL 436
    Length:436
    Mass (Da):46,180
    Last modified:November 8, 2005 - v2
    Checksum:i94D7F534A87BAB18
    GO

    Sequence cautioni

    The sequence AAV47913.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY596297 Genomic DNA. Translation: AAV47913.1. Different initiation.
    RefSeqiYP_137619.1. NC_006396.1.

    Genome annotation databases

    EnsemblBacteriaiAAV47913; AAV47913; rrnAC3210.
    GeneIDi3129274.
    KEGGihma:rrnAC3210.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY596297 Genomic DNA. Translation: AAV47913.1 . Different initiation.
    RefSeqi YP_137619.1. NC_006396.1.

    3D structure databases

    ProteinModelPortali Q5UXU0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272569.rrnAC3210.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAV47913 ; AAV47913 ; rrnAC3210 .
    GeneIDi 3129274.
    KEGGi hma:rrnAC3210.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100402.
    KOi K01810.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci HMAR272569:GJDH-2882-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.

    Entry informationi

    Entry nameiG6PI_HALMA
    AccessioniPrimary (citable) accession number: Q5UXU0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2005
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 54 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3