Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5UXM8

- HTR1_HALMA

UniProt

Q5UXM8 - HTR1_HALMA

Protein

Sensory rhodopsin I transducer

Gene

htr1

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 2 (14 May 2014)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Transduces signals from the phototaxis receptor sensory rhodopsin I (Sop1).1 Publication

    GO - Molecular functioni

    1. signal transducer activity Source: UniProtKB-KW

    GO - Biological processi

    1. chemotaxis Source: InterPro

    Keywords - Molecular functioni

    Transducer

    Enzyme and pathway databases

    BioCyciHMAR272569:GJDH-2945-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sensory rhodopsin I transducer
    Alternative name(s):
    MCP domain signal transducer 1
    Short name:
    HmHtrI
    Gene namesi
    Name:htr1
    Ordered Locus Names:rrnAC3281
    OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
    Taxonomic identifieri272569 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula
    ProteomesiUP000001169: Chromosome I

    Subcellular locationi

    Cell membrane 1 Publication; Multi-pass membrane protein 1 Publication

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 528528Sensory rhodopsin I transducerPRO_0000428857Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei259 – 2591Glutamate methyl ester (Glu)By similarity

    Keywords - PTMi

    Methylation

    Expressioni

    Inductioni

    Expressed constitutively throughout the growth phases, both in presence and absence of white light.1 Publication

    Interactioni

    Subunit structurei

    Interacts with Sop1.1 Publication

    Protein-protein interaction databases

    STRINGi272569.rrnAC3281.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5UXM8.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei11 – 3121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei35 – 5521HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini55 – 10753HAMP 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini142 – 19554HAMP 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini214 – 455242Methyl-accepting transducerPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi156 – 1594Poly-Ala

    Sequence similaritiesi

    Contains 2 HAMP domains.PROSITE-ProRule annotation
    Contains 1 methyl-accepting transducer domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0840.
    HOGENOMiHOG000038479.
    OMAiMASHIAT.

    Family and domain databases

    InterProiIPR004090. Chemotax_Me-accpt_rcpt.
    IPR003660. HAMP_linker_domain.
    IPR004089. MCPsignal_dom.
    [Graphical view]
    PfamiPF00672. HAMP. 1 hit.
    PF00015. MCPsignal. 1 hit.
    [Graphical view]
    PRINTSiPR00260. CHEMTRNSDUCR.
    SMARTiSM00304. HAMP. 3 hits.
    SM00283. MA. 1 hit.
    [Graphical view]
    PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
    PS50885. HAMP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5UXM8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTISSVKQSY GAKLGVGYIA TATLLITVGV VTQDVASTVV AGIAGLLTLG    50
    SINAAETVAS ITELSAQTQR VADGDLDIEI DSTRTDEFGD LADSIEQMRV 100
    SLRDRLSEME AARADLEQAQ TDANEAQAEA EAAEEEAKEL ATAYQDIATE 150
    YGTVMAAAAD GDLTQRVDVA TEYDAMETVG QSFNRMMDEL QETIETVTAV 200
    SKRITTETDE ITETSRRVQQ EVDAAVETVA DIQTQATDQQ TKLESAAVDI 250
    QDVSASAEEI AATIDDLADR SSEVEEASSD ARTASETALT EMDQIQADAA 300
    DAVTQVETLQ QRMAEITDIA DIISEIAEQT NMLALNASIE AARAGGQGSG 350
    ADGNGFSVVA DEVKSLAEET QSRADEIATV IAEVSEQTEE VTDSIQATET 400
    RVETGTETVE SALSEIATIA EAVDDISASI EEMRETTSEQ ADTVQATADS 450
    IADVTEASAE TATTAEEMST QIRRQRDVVK SISDSLDSFR ETAVDDLESR 500
    VRLFTINTDT TAASQTRAVG SPSIGGDD 528
    Length:528
    Mass (Da):55,853
    Last modified:May 14, 2014 - v2
    Checksum:iEF53B3B6C053C55E
    GO

    Sequence cautioni

    The sequence AAV47975.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY596297 Genomic DNA. Translation: AAV47975.1. Different initiation.
    RefSeqiYP_137681.1. NC_006396.1.

    Genome annotation databases

    EnsemblBacteriaiAAV47975; AAV47975; rrnAC3281.
    GeneIDi3128039.
    KEGGihma:rrnAC3281.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY596297 Genomic DNA. Translation: AAV47975.1 . Different initiation.
    RefSeqi YP_137681.1. NC_006396.1.

    3D structure databases

    ProteinModelPortali Q5UXM8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272569.rrnAC3281.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAV47975 ; AAV47975 ; rrnAC3281 .
    GeneIDi 3128039.
    KEGGi hma:rrnAC3281.

    Phylogenomic databases

    eggNOGi COG0840.
    HOGENOMi HOG000038479.
    OMAi MASHIAT.

    Enzyme and pathway databases

    BioCyci HMAR272569:GJDH-2945-MONOMER.

    Family and domain databases

    InterProi IPR004090. Chemotax_Me-accpt_rcpt.
    IPR003660. HAMP_linker_domain.
    IPR004089. MCPsignal_dom.
    [Graphical view ]
    Pfami PF00672. HAMP. 1 hit.
    PF00015. MCPsignal. 1 hit.
    [Graphical view ]
    PRINTSi PR00260. CHEMTRNSDUCR.
    SMARTi SM00304. HAMP. 3 hits.
    SM00283. MA. 1 hit.
    [Graphical view ]
    PROSITEi PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
    PS50885. HAMP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
    2. Cited for: INDUCTION, IDENTIFICATION.
    3. "A transducer for microbial sensory rhodopsin that adopts GTG as a start codon is identified in Haloarcula marismortui."
      Fu H.Y., Lu Y.H., Yi H.P., Yang C.S.
      J. Photochem. Photobiol. B 121:15-22(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION, FUNCTION, INTERACTION WITH SOP1.

    Entry informationi

    Entry nameiHTR1_HALMA
    AccessioniPrimary (citable) accession number: Q5UXM8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 14, 2014
    Last sequence update: May 14, 2014
    Last modified: October 1, 2014
    This is version 55 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3