Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sensory rhodopsin I transducer

Gene

htr1

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Transduces signals from the phototaxis receptor sensory rhodopsin I (Sop1).1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transducer

Enzyme and pathway databases

BioCyciHMAR272569:GJDH-2945-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sensory rhodopsin I transducer
Alternative name(s):
MCP domain signal transducer 1
Short name:
HmHtrI
Gene namesi
Name:htr1
Ordered Locus Names:rrnAC3281
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula
ProteomesiUP000001169 Componenti: Chromosome I

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei11 – 3121HelicalSequence AnalysisAdd
BLAST
Transmembranei35 – 5521HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 528528Sensory rhodopsin I transducerPRO_0000428857Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei259 – 2591Glutamate methyl ester (Glu)By similarity

Keywords - PTMi

Methylation

Expressioni

Inductioni

Expressed constitutively throughout the growth phases, both in presence and absence of white light.1 Publication

Interactioni

Subunit structurei

Interacts with Sop1.1 Publication

Protein-protein interaction databases

STRINGi272569.rrnAC3281.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini55 – 10753HAMP 1PROSITE-ProRule annotationAdd
BLAST
Domaini142 – 19554HAMP 2PROSITE-ProRule annotationAdd
BLAST
Domaini214 – 455242Methyl-accepting transducerPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi156 – 1594Poly-Ala

Sequence similaritiesi

Contains 2 HAMP domains.PROSITE-ProRule annotation
Contains 1 methyl-accepting transducer domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0840.
HOGENOMiHOG000038479.

Family and domain databases

InterProiIPR004090. Chemotax_Me-accpt_rcpt.
IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view]
PfamiPF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view]
PRINTSiPR00260. CHEMTRNSDUCR.
SMARTiSM00304. HAMP. 3 hits.
SM00283. MA. 1 hit.
[Graphical view]
PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5UXM8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTISSVKQSY GAKLGVGYIA TATLLITVGV VTQDVASTVV AGIAGLLTLG
60 70 80 90 100
SINAAETVAS ITELSAQTQR VADGDLDIEI DSTRTDEFGD LADSIEQMRV
110 120 130 140 150
SLRDRLSEME AARADLEQAQ TDANEAQAEA EAAEEEAKEL ATAYQDIATE
160 170 180 190 200
YGTVMAAAAD GDLTQRVDVA TEYDAMETVG QSFNRMMDEL QETIETVTAV
210 220 230 240 250
SKRITTETDE ITETSRRVQQ EVDAAVETVA DIQTQATDQQ TKLESAAVDI
260 270 280 290 300
QDVSASAEEI AATIDDLADR SSEVEEASSD ARTASETALT EMDQIQADAA
310 320 330 340 350
DAVTQVETLQ QRMAEITDIA DIISEIAEQT NMLALNASIE AARAGGQGSG
360 370 380 390 400
ADGNGFSVVA DEVKSLAEET QSRADEIATV IAEVSEQTEE VTDSIQATET
410 420 430 440 450
RVETGTETVE SALSEIATIA EAVDDISASI EEMRETTSEQ ADTVQATADS
460 470 480 490 500
IADVTEASAE TATTAEEMST QIRRQRDVVK SISDSLDSFR ETAVDDLESR
510 520
VRLFTINTDT TAASQTRAVG SPSIGGDD
Length:528
Mass (Da):55,853
Last modified:May 14, 2014 - v2
Checksum:iEF53B3B6C053C55E
GO

Sequence cautioni

The sequence AAV47975.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY596297 Genomic DNA. Translation: AAV47975.1. Different initiation.
RefSeqiWP_011224715.1. NC_006396.1.
YP_137681.1. NC_006396.1.

Genome annotation databases

EnsemblBacteriaiAAV47975; AAV47975; rrnAC3281.
GeneIDi3128039.
KEGGihma:rrnAC3281.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY596297 Genomic DNA. Translation: AAV47975.1. Different initiation.
RefSeqiWP_011224715.1. NC_006396.1.
YP_137681.1. NC_006396.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272569.rrnAC3281.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV47975; AAV47975; rrnAC3281.
GeneIDi3128039.
KEGGihma:rrnAC3281.

Phylogenomic databases

eggNOGiCOG0840.
HOGENOMiHOG000038479.

Enzyme and pathway databases

BioCyciHMAR272569:GJDH-2945-MONOMER.

Family and domain databases

InterProiIPR004090. Chemotax_Me-accpt_rcpt.
IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view]
PfamiPF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view]
PRINTSiPR00260. CHEMTRNSDUCR.
SMARTiSM00304. HAMP. 3 hits.
SM00283. MA. 1 hit.
[Graphical view]
PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
  2. Cited for: INDUCTION, IDENTIFICATION.
  3. "A transducer for microbial sensory rhodopsin that adopts GTG as a start codon is identified in Haloarcula marismortui."
    Fu H.Y., Lu Y.H., Yi H.P., Yang C.S.
    J. Photochem. Photobiol. B 121:15-22(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, FUNCTION, INTERACTION WITH SOP1.

Entry informationi

Entry nameiHTR1_HALMA
AccessioniPrimary (citable) accession number: Q5UXM8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 14, 2014
Last sequence update: May 14, 2014
Last modified: May 27, 2015
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.