Q5UXH0 (KCY_HALMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	rrnAC3343

Organism

Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) [Complete proteome] [HAMAP]

Taxonomic identifier

272569 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloarcula

Protein attributes

Sequence length	192 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00239
Subcellular location	Cytoplasm By similarity HAMAP MF_00239.
Sequence similarities	Belongs to the cytidylate kinase family. Type 2 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro shikimate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 192	192	Cytidylate kinase HAMAP MF_00239		PRO_0000132010
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5UXH0 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: 4C897245226EA17A	FASTA	192	21,555
	10 20 30 40 50 60 MLITVSGPAG SGKSTLAKSL ADALNYEHVS GGDIFRSLAE ERGMTPLELN KAAEEDDQID 70 80 90 100 110 120 RDLDRKLRDI AAERDDLVLE SRLAGWMAGE YADMKLWLTA PLDVRADRIA TRENKPFEQA 130 140 150 160 170 180 KTETRERGDS EAQRYSDYYD IDFDDLSIYD LSVNTARWDP QGVLSVTLHA VESYSPDGDE 190 GKAPVENIRY EF

References

[1]

"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea." Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V. Genome Res. 14:2221-2234(2004) [PubMed: 15520287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY596297 Genomic DNA. Translation: AAV48033.1.
RefSeq	YP_137739.1. NC_006396.1.
3D structure databases
ProteinModelPortal	Q5UXH0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3128303.
GenomeReviews	Gene locus rrnAC3343 in contig AY596297_GR.
KEGG	hma:rrnAC3343.
NMPDR	fig|272569.1.peg.3029.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG578180.
OMA	CAGFIFR.
PhylomeDB	Q5UXH0.
ProtClustDB	PRK04182.
Enzyme and pathway databases
BioCyc	HMAR272569:RRNAC3343-MONOMER.
Family and domain databases
HAMAP	MF_00239. Cytidyl_kinase_type2. [Tree]
InterPro	IPR011892. Cyt_kin_arch. IPR000623. Shikimate_kinase. [Graphical view]
KO	K00945.
Pfam	PF01202. SKI. 1 hit. [Graphical view]
TIGRFAMs	TIGR02173. Cyt_kin_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_HALMA

Accession

Primary (citable) accession number: Q5UXH0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	December 7, 2004
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program