Q5UXA4 (Q5UXA4_HALMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Isocitrate dehydrogenase EMBL AAV48099.1
EC=1.1.1.42 EMBL AAV48099.1

Gene names

Name:	icd EMBL AAV48099.1
Ordered Locus Names:	rrnAC3419 EMBL AAV48099.1

Organism

Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) [Complete proteome] [HAMAP] EMBL AAV48099.1

Taxonomic identifier

272569 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloarcula › Haloarcula marismortui

Protein attributes

Sequence length	420 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004444 EMBL AAV48099.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	NAD binding Inferred from electronic annotation. Source: InterPro isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5UXA4 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: 861C32CAFD038EAB	FASTA	420	46,316
	10 20 30 40 50 60 MGYDYDKVEV PDEGQQIQVT EDDELDVPEN PIIPIIHGDG IGTDVGPAAQ KVLEAAANAT 70 80 90 100 110 120 GRDISWMRIY AGQSARDKYD ENLPDDTVEA IKEFNVAIKG PLTTPVGAGF RSLNVALRKT 130 140 150 160 170 180 LDLYANVRPT YHIEGVPSPV KDPEEMDMVT FRENTEDVYA GIEWEAGTDE VEEVKEFVED 190 200 210 220 230 240 EMNFDETIHD GPVGIGVKPI TEFGTKRLVR EAIDYALEED RDSVTLVHKG NIMKFTEGAF 250 260 270 280 290 300 RDWGYEVAEE EYGEHVITED ELWDEYDGEA PEDSLVVNDR IADNMLQQLL TRTDEYDVIA 310 320 330 340 350 360 TMNLNGDYMS DAAGAQIGGL GIAPGANFGS ARCLAEPVHG SAPKYAGEDK VNPTAMILSG 370 380 390 400 410 420 RLMLEYMGWK DAGQLVRDAV EETISSGNVT YDLERQIEGG TKLATSEFAE KVVENIEKLA

References

[1]

"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea." Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V. Genome Res. 14:2221-2234(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY596297 Genomic DNA. Translation: AAV48099.1.
RefSeq	YP_137805.1. NC_006396.1.
3D structure databases
ProteinModelPortal	Q5UXA4.
SMR	Q5UXA4. Positions 5-419.
ModBase	Search...
Protein-protein interaction databases
STRING	272569.rrnAC3419.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAV48099; AAV48099; rrnAC3419.
GeneID	3127607.
KEGG	hma:rrnAC3419.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0538.
HOGENOM	HOG000021113.
KO	K00031.
OMA	FRDWGYE.
ProtClustDB	CLSK511548.
Enzyme and pathway databases
BioCyc	HMAR272569:GJDH-3071-MONOMER. MetaCyc:MONOMER-16258.
Family and domain databases
Gene3D	3.40.718.10. 1 hit.
InterPro	IPR019818. IsoCit/isopropylmalate_DH_CS. IPR001804. Isocitrate/isopropylmalate_DH. IPR004439. Isocitrate_DH_NADP_dimer_prok. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
PANTHER	PTHR11835. PTHR11835. 1 hit.
Pfam	PF00180. Iso_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR00183. prok_nadp_idh. 1 hit.
PROSITE	PS00470. IDH_IMDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5UXA4_HALMA

Accession

Primary (citable) accession number: Q5UXA4

Entry history

Integrated into UniProtKB/TrEMBL:	December 7, 2004
Last sequence update:	December 7, 2004
Last modified:	May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)