Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5UR02

- CHLE_MIMIV

UniProt

Q5UR02 - CHLE_MIMIV

Protein

Probable cholinesterase

Gene

MIMI_L906

Organism
Acanthamoeba polyphaga mimivirus (APMV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    May be involved in the disruption of the host membrane.

    Catalytic activityi

    An acylcholine + H2O = choline + a carboxylate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei217 – 2171Acyl-ester intermediatePROSITE-ProRule annotation
    Active sitei337 – 3371Charge relay systemBy similarity
    Active sitei451 – 4511Charge relay systemBy similarity

    GO - Molecular functioni

    1. cholinesterase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Serine esterase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable cholinesterase (EC:3.1.1.8)
    Alternative name(s):
    Acylcholine acylhydrolase
    Gene namesi
    Ordered Locus Names:MIMI_L906
    OrganismiAcanthamoeba polyphaga mimivirus (APMV)
    Taxonomic identifieri212035 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
    Virus hostiAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]
    ProteomesiUP000001134: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 579560Probable cholinesterasePRO_0000041775Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi77 – 771N-linked (GlcNAc...); by hostSequence Analysis
    Glycosylationi144 – 1441N-linked (GlcNAc...); by hostSequence Analysis
    Glycosylationi257 – 2571N-linked (GlcNAc...); by hostSequence Analysis
    Glycosylationi269 – 2691N-linked (GlcNAc...); by hostSequence Analysis
    Glycosylationi283 – 2831N-linked (GlcNAc...); by hostSequence Analysis
    Glycosylationi373 – 3731N-linked (GlcNAc...); by hostSequence Analysis
    Glycosylationi394 – 3941N-linked (GlcNAc...); by hostSequence Analysis
    Glycosylationi469 – 4691N-linked (GlcNAc...); by hostSequence Analysis

    Keywords - PTMi

    Glycoprotein

    Structurei

    3D structure databases

    ProteinModelPortaliQ5UR02.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR002018. CarbesteraseB.
    IPR019826. Carboxylesterase_B_AS.
    IPR019819. Carboxylesterase_B_CS.
    [Graphical view]
    PfamiPF00135. COesterase. 1 hit.
    [Graphical view]
    SUPFAMiSSF53474. SSF53474. 1 hit.
    PROSITEiPS00122. CARBOXYLESTERASE_B_1. 1 hit.
    PS00941. CARBOXYLESTERASE_B_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q5UR02-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTDHKIIMLL LLGIYCIQAT QFTQVNIDNG PIKGTLQYVE GRAIRVFKGI    50
    PFAEPPVNNL RWKAPVPYTK KWHNPLNTTE YKPKCPQYVA PGTVPEPRGI 100
    SEDCLYTNVW APVPEYHGET FPVMVWIHGG AFISGSPEDF GVGNFSILAV 150
    TKRIIIVAAS YRVNAFGFFS SELLGKSQLE ARGVYGLLDQ RLGLKWVKNN 200
    IAAFGGKSKD ITIYGQSAGG ISVCLQAVTP LNDLPGEKLF TRVIGSSGYC 250
    DILPMTNNSA DAGLVQKLNC TTKECLYALP WQNITNAVGP GFLSFQPTVG 300
    INKFLPDQPI SLLADRTNPR SKNFVPDIYM QGFTANEGTF VLYNYFPQTY 350
    DNPNTPGFPT QQMADALSIA SGNYSAEFYY NDLAPLYSTE YNSNVTYPGQ 400
    GFISRVDDIM ACNTRRNMIY WQQSKKTKAH SWYFDSAPDT HIYPSWTKVF 450
    HESDVFYVAR RCDGLWCTNL TCQQDNLGKT MNIYWNSAIR AASLTPKNKM 500
    DNLRDVPVWP QYGKNEVVMH FTAVGENKGP QTSVLFSSII SADGDYQYLQ 550
    RCKILDRVRA EYYNIPALDP ETYLNACSK 579
    Length:579
    Mass (Da):64,868
    Last modified:December 7, 2004 - v1
    Checksum:i1DD9D68940B8B9E6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY653733 Genomic DNA. Translation: AAV51163.1.
    RefSeqiYP_003987440.1. NC_014649.1.

    Genome annotation databases

    GeneIDi9925575.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY653733 Genomic DNA. Translation: AAV51163.1 .
    RefSeqi YP_003987440.1. NC_014649.1.

    3D structure databases

    ProteinModelPortali Q5UR02.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 9925575.

    Family and domain databases

    Gene3Di 3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR002018. CarbesteraseB.
    IPR019826. Carboxylesterase_B_AS.
    IPR019819. Carboxylesterase_B_CS.
    [Graphical view ]
    Pfami PF00135. COesterase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53474. SSF53474. 1 hit.
    PROSITEi PS00122. CARBOXYLESTERASE_B_1. 1 hit.
    PS00941. CARBOXYLESTERASE_B_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Rowbotham-Bradford.

    Entry informationi

    Entry nameiCHLE_MIMIV
    AccessioniPrimary (citable) accession number: Q5UR02
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 13, 2005
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3