SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5UR02

- CHLE_MIMIV

UniProt

Q5UR02 - CHLE_MIMIV

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Probable cholinesterase
Gene
MIMI_L906
Organism
Acanthamoeba polyphaga mimivirus (APMV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

May be involved in the disruption of the host membrane.

Catalytic activityi

An acylcholine + H2O = choline + a carboxylate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei217 – 2171Acyl-ester intermediate By similarity
Active sitei337 – 3371Charge relay system By similarity
Active sitei451 – 4511Charge relay system By similarity

GO - Molecular functioni

  1. cholinesterase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Serine esterase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cholinesterase (EC:3.1.1.8)
Alternative name(s):
Acylcholine acylhydrolase
Gene namesi
Ordered Locus Names:MIMI_L906
OrganismiAcanthamoeba polyphaga mimivirus (APMV)
Taxonomic identifieri212035 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
Virus hostiAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]
ProteomesiUP000001134: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919 Reviewed prediction
Add
BLAST
Chaini20 – 579560Probable cholinesterase
PRO_0000041775Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi77 – 771N-linked (GlcNAc...); by host Reviewed prediction
Glycosylationi144 – 1441N-linked (GlcNAc...); by host Reviewed prediction
Glycosylationi257 – 2571N-linked (GlcNAc...); by host Reviewed prediction
Glycosylationi269 – 2691N-linked (GlcNAc...); by host Reviewed prediction
Glycosylationi283 – 2831N-linked (GlcNAc...); by host Reviewed prediction
Glycosylationi373 – 3731N-linked (GlcNAc...); by host Reviewed prediction
Glycosylationi394 – 3941N-linked (GlcNAc...); by host Reviewed prediction
Glycosylationi469 – 4691N-linked (GlcNAc...); by host Reviewed prediction

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ5UR02.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019826. Carboxylesterase_B_AS.
IPR019819. Carboxylesterase_B_CS.
[Graphical view]
PfamiPF00135. COesterase. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00122. CARBOXYLESTERASE_B_1. 1 hit.
PS00941. CARBOXYLESTERASE_B_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5UR02-1 [UniParc]FASTAAdd to Basket

« Hide

MTDHKIIMLL LLGIYCIQAT QFTQVNIDNG PIKGTLQYVE GRAIRVFKGI    50
PFAEPPVNNL RWKAPVPYTK KWHNPLNTTE YKPKCPQYVA PGTVPEPRGI 100
SEDCLYTNVW APVPEYHGET FPVMVWIHGG AFISGSPEDF GVGNFSILAV 150
TKRIIIVAAS YRVNAFGFFS SELLGKSQLE ARGVYGLLDQ RLGLKWVKNN 200
IAAFGGKSKD ITIYGQSAGG ISVCLQAVTP LNDLPGEKLF TRVIGSSGYC 250
DILPMTNNSA DAGLVQKLNC TTKECLYALP WQNITNAVGP GFLSFQPTVG 300
INKFLPDQPI SLLADRTNPR SKNFVPDIYM QGFTANEGTF VLYNYFPQTY 350
DNPNTPGFPT QQMADALSIA SGNYSAEFYY NDLAPLYSTE YNSNVTYPGQ 400
GFISRVDDIM ACNTRRNMIY WQQSKKTKAH SWYFDSAPDT HIYPSWTKVF 450
HESDVFYVAR RCDGLWCTNL TCQQDNLGKT MNIYWNSAIR AASLTPKNKM 500
DNLRDVPVWP QYGKNEVVMH FTAVGENKGP QTSVLFSSII SADGDYQYLQ 550
RCKILDRVRA EYYNIPALDP ETYLNACSK 579
Length:579
Mass (Da):64,868
Last modified:December 7, 2004 - v1
Checksum:i1DD9D68940B8B9E6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY653733 Genomic DNA. Translation: AAV51163.1.
RefSeqiYP_003987440.1. NC_014649.1.

Genome annotation databases

GeneIDi9925575.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY653733 Genomic DNA. Translation: AAV51163.1 .
RefSeqi YP_003987440.1. NC_014649.1.

3D structure databases

ProteinModelPortali Q5UR02.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9925575.

Family and domain databases

Gene3Di 3.40.50.1820. 1 hit.
InterProi IPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019826. Carboxylesterase_B_AS.
IPR019819. Carboxylesterase_B_CS.
[Graphical view ]
Pfami PF00135. COesterase. 1 hit.
[Graphical view ]
SUPFAMi SSF53474. SSF53474. 1 hit.
PROSITEi PS00122. CARBOXYLESTERASE_B_1. 1 hit.
PS00941. CARBOXYLESTERASE_B_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Rowbotham-Bradford.

Entry informationi

Entry nameiCHLE_MIMIV
AccessioniPrimary (citable) accession number: Q5UR02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: December 7, 2004
Last modified: June 11, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi