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Q5UQV6 (YR368_MIMIV) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable FAD-linked sulfhydryl oxidase R368

EC=1.8.3.2
Gene names
Ordered Locus Names:MIMI_R368
OrganismAcanthamoeba polyphaga mimivirus (APMV) [Reference proteome]
Taxonomic identifier212035 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
Virus hostAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]

Protein attributes

Sequence length143 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation By similarity.

Catalytic activity

2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.

Cofactor

FAD By similarity.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Contains 1 ERV/ALR sulfhydryl oxidase domain.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   PTMDisulfide bond
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionthiol oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 143143Probable FAD-linked sulfhydryl oxidase R368
PRO_0000309199

Regions

Transmembrane117 – 13721Helical; Potential
Domain10 – 10495ERV/ALR sulfhydryl oxidase

Amino acid modifications

Disulfide bond46 ↔ 49Redox-active Potential

Sequences

Sequence LengthMass (Da)Tools
Q5UQV6 [UniParc].

Last modified December 7, 2004. Version 1.
Checksum: CA9BCD24A6933889

FASTA14316,981
        10         20         30         40         50         60 
MSPEQWGIYG WTFSHAVALG YPINPTEEDK LRYYTFFNSY RYVLPCGKCR INYADHLNKY 

        70         80         90        100        110        120 
PLTDEVLSSR ENLVKWTIDI HNVVNYYTGK KMLTYPEAIE AIEKTLTPKK KSSYNWFFII 

       130        140 
LIIIGIIVII YLMYIVFKKK LNK 

« Hide

References

[1]"The 1.2-megabase genome sequence of Mimivirus."
Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H., La Scola B., Susan M., Claverie J.-M.
Science 306:1344-1350(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Rowbotham-Bradford.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY653733 Genomic DNA. Translation: AAV50637.1.
RefSeqYP_003986873.1. NC_014649.1.

3D structure databases

ProteinModelPortalQ5UQV6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID9924989.

Family and domain databases

Gene3D1.20.120.310. 1 hit.
InterProIPR017905. ERV/ALR_sulphydryl_oxidase.
[Graphical view]
PfamPF04777. Evr1_Alr. 1 hit.
[Graphical view]
SUPFAMSSF69000. SSF69000. 1 hit.
PROSITEPS51324. ERV_ALR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYR368_MIMIV
AccessionPrimary (citable) accession number: Q5UQV6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: December 7, 2004
Last modified: February 19, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families