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Protein

Probable ribonuclease 3

Gene

MIMI_R343

Organism
Acanthamoeba polyphaga mimivirus (APMV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Digests double-stranded RNA.By similarity

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ribonuclease 3 (EC:3.1.26.3)
Alternative name(s):
Ribonuclease III
Short name:
RNase III
Gene namesi
Ordered Locus Names:MIMI_R343
OrganismiAcanthamoeba polyphaga mimivirus (APMV)
Taxonomic identifieri212035 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
Virus hostiAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]
Proteomesi
  • UP000001134 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002439801 – 538Probable ribonuclease 3Add BLAST538

Structurei

3D structure databases

ProteinModelPortaliQ5UQT7.
SMRiQ5UQT7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 149RNase III 1Add BLAST126
Domaini238 – 381RNase III 2Add BLAST144
Domaini408 – 477DRBMAdd BLAST70

Sequence similaritiesi

Belongs to the ribonuclease III family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

OrthoDBiVOG090000RK.

Family and domain databases

CDDicd00593. RIBOc. 2 hits.
Gene3Di1.10.1520.10. 2 hits.
HAMAPiMF_00104. RNase_III. 1 hit.
InterProiView protein in InterPro
IPR014720. dsRBD_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
PfamiView protein in Pfam
PF00035. dsrm. 2 hits.
PF14622. Ribonucleas_3_3. 2 hits.
SMARTiView protein in SMART
SM00358. DSRM. 2 hits.
SM00535. RIBOc. 2 hits.
SUPFAMiSSF69065. SSF69065. 2 hits.
PROSITEiView protein in PROSITE
PS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5UQT7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKFQNYYNN DDNVINYPYI DYIIKSYIPE YYVDTNRRKY VDMHIFEEAM
60 70 80 90 100
LHVSTIYEES DKTYERLEYL GDAIFHMIIT EYFYHRYNEE NEGFLTRLRI
110 120 130 140 150
RIERGDSMVE LSKNLGLNNF VQIYGISLND HILEDIFESF IGAFYLNFGM
160 170 180 190 200
KYTRLFIIKL IEKHKNLSEL IAYDDNYKDL LLRYFHQMKW GHPKYIEEIV
210 220 230 240 250
IDPKNNQRNK FISKVKNPFD KVIGIGSAST KKKSEQLASQ MALTNLGVII
260 270 280 290 300
DGEIDTDWIN KIEKIETEAT QTEIKDKKPM SVFNPNNKLL SKNTIKNLLL
310 320 330 340 350
QYNTKLPTID IDLKLFYEAM THRSYLIRKN LPNRDVPKSK SIVRLQKKSN
360 370 380 390 400
ERLQFLGDAV IHFIIGEYLF NKYADSGEGY LTRLRCKLEN SESLFFLAKQ
410 420 430 440 450
SDISSYLLIS QNIEVLHGRE NVNIIGGGLE AFVGALYLNI GLGTVKQFLL
460 470 480 490 500
EIMRIELDIN QIAENETNYK DLILQLYNKN KWGHPVYKIL KEEGPDHCKI
510 520 530
FTMGLYLGNK LMGIGKASSK KKAEQIASKK MYQNYINN
Length:538
Mass (Da):63,058
Last modified:December 7, 2004 - v1
Checksum:iBDC3AD6D0CB4E904
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY653733 Genomic DNA. Translation: AAV50612.1.
RefSeqiYP_003986845.1. NC_014649.1.

Genome annotation databases

GeneIDi9924960.
KEGGivg:9924960.

Similar proteinsi

Entry informationi

Entry nameiRNC_MIMIV
AccessioniPrimary (citable) accession number: Q5UQT7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 7, 2004
Last modified: September 27, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families