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Q5UQT7

- RNC_MIMIV

UniProt

Q5UQT7 - RNC_MIMIV

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Protein

Probable ribonuclease 3

Gene
MIMI_R343
Organism
Acanthamoeba polyphaga mimivirus (APMV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Digests double-stranded RNA By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation

GO - Molecular functioni

  1. ribonuclease III activity Source: UniProtKB-EC
  2. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. RNA processing Source: InterPro
  2. rRNA catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ribonuclease 3 (EC:3.1.26.3)
Alternative name(s):
Ribonuclease III
Short name:
RNase III
Gene namesi
Ordered Locus Names:MIMI_R343
OrganismiAcanthamoeba polyphaga mimivirus (APMV)
Taxonomic identifieri212035 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
Virus hostiAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]
ProteomesiUP000001134: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 538538Probable ribonuclease 3UniRule annotationPRO_0000243980Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ5UQT7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 149126RNase III 1Add
BLAST
Domaini238 – 381144RNase III 2Add
BLAST
Domaini408 – 47770DRBMAdd
BLAST

Sequence similaritiesi

Contains 2 RNase III domains.

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di1.10.1520.10. 2 hits.
3.30.160.20. 2 hits.
HAMAPiMF_00104. RNase_III.
InterProiIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERiPTHR11207. PTHR11207. 1 hit.
PfamiPF00035. dsrm. 2 hits.
PF00636. Ribonuclease_3. 2 hits.
[Graphical view]
SMARTiSM00358. DSRM. 2 hits.
SM00535. RIBOc. 2 hits.
[Graphical view]
SUPFAMiSSF69065. SSF69065. 2 hits.
PROSITEiPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5UQT7-1 [UniParc]FASTAAdd to Basket

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MSKFQNYYNN DDNVINYPYI DYIIKSYIPE YYVDTNRRKY VDMHIFEEAM    50
LHVSTIYEES DKTYERLEYL GDAIFHMIIT EYFYHRYNEE NEGFLTRLRI 100
RIERGDSMVE LSKNLGLNNF VQIYGISLND HILEDIFESF IGAFYLNFGM 150
KYTRLFIIKL IEKHKNLSEL IAYDDNYKDL LLRYFHQMKW GHPKYIEEIV 200
IDPKNNQRNK FISKVKNPFD KVIGIGSAST KKKSEQLASQ MALTNLGVII 250
DGEIDTDWIN KIEKIETEAT QTEIKDKKPM SVFNPNNKLL SKNTIKNLLL 300
QYNTKLPTID IDLKLFYEAM THRSYLIRKN LPNRDVPKSK SIVRLQKKSN 350
ERLQFLGDAV IHFIIGEYLF NKYADSGEGY LTRLRCKLEN SESLFFLAKQ 400
SDISSYLLIS QNIEVLHGRE NVNIIGGGLE AFVGALYLNI GLGTVKQFLL 450
EIMRIELDIN QIAENETNYK DLILQLYNKN KWGHPVYKIL KEEGPDHCKI 500
FTMGLYLGNK LMGIGKASSK KKAEQIASKK MYQNYINN 538
Length:538
Mass (Da):63,058
Last modified:December 7, 2004 - v1
Checksum:iBDC3AD6D0CB4E904
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY653733 Genomic DNA. Translation: AAV50612.1.
RefSeqiYP_003986845.1. NC_014649.1.

Genome annotation databases

GeneIDi9924960.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY653733 Genomic DNA. Translation: AAV50612.1 .
RefSeqi YP_003986845.1. NC_014649.1.

3D structure databases

ProteinModelPortali Q5UQT7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9924960.

Family and domain databases

Gene3Di 1.10.1520.10. 2 hits.
3.30.160.20. 2 hits.
HAMAPi MF_00104. RNase_III.
InterProi IPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view ]
PANTHERi PTHR11207. PTHR11207. 1 hit.
Pfami PF00035. dsrm. 2 hits.
PF00636. Ribonuclease_3. 2 hits.
[Graphical view ]
SMARTi SM00358. DSRM. 2 hits.
SM00535. RIBOc. 2 hits.
[Graphical view ]
SUPFAMi SSF69065. SSF69065. 2 hits.
PROSITEi PS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Rowbotham-Bradford.

Entry informationi

Entry nameiRNC_MIMIV
AccessioniPrimary (citable) accession number: Q5UQT7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 7, 2004
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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