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Q5UQT7

- RNC_MIMIV

UniProt

Q5UQT7 - RNC_MIMIV

Protein

Probable ribonuclease 3

Gene

MIMI_R343

Organism
Acanthamoeba polyphaga mimivirus (APMV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    Digests double-stranded RNA.By similarity

    Catalytic activityi

    Endonucleolytic cleavage to 5'-phosphomonoester.

    GO - Molecular functioni

    1. ribonuclease III activity Source: UniProtKB-EC
    2. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. RNA processing Source: InterPro
    2. rRNA catabolic process Source: InterPro

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable ribonuclease 3 (EC:3.1.26.3)
    Alternative name(s):
    Ribonuclease III
    Short name:
    RNase III
    Gene namesi
    Ordered Locus Names:MIMI_R343
    OrganismiAcanthamoeba polyphaga mimivirus (APMV)
    Taxonomic identifieri212035 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
    Virus hostiAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]
    ProteomesiUP000001134: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 538538Probable ribonuclease 3PRO_0000243980Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ5UQT7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini24 – 149126RNase III 1Add
    BLAST
    Domaini238 – 381144RNase III 2Add
    BLAST
    Domaini408 – 47770DRBMAdd
    BLAST

    Sequence similaritiesi

    Contains 2 RNase III domains.Curated

    Keywords - Domaini

    Repeat

    Family and domain databases

    Gene3Di1.10.1520.10. 2 hits.
    3.30.160.20. 2 hits.
    HAMAPiMF_00104. RNase_III.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR011907. RNase_III.
    IPR000999. RNase_III_dom.
    [Graphical view]
    PANTHERiPTHR11207. PTHR11207. 1 hit.
    PfamiPF00035. dsrm. 2 hits.
    PF00636. Ribonuclease_3. 2 hits.
    [Graphical view]
    SMARTiSM00358. DSRM. 2 hits.
    SM00535. RIBOc. 2 hits.
    [Graphical view]
    SUPFAMiSSF69065. SSF69065. 2 hits.
    PROSITEiPS50137. DS_RBD. 1 hit.
    PS00517. RNASE_3_1. 1 hit.
    PS50142. RNASE_3_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5UQT7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKFQNYYNN DDNVINYPYI DYIIKSYIPE YYVDTNRRKY VDMHIFEEAM    50
    LHVSTIYEES DKTYERLEYL GDAIFHMIIT EYFYHRYNEE NEGFLTRLRI 100
    RIERGDSMVE LSKNLGLNNF VQIYGISLND HILEDIFESF IGAFYLNFGM 150
    KYTRLFIIKL IEKHKNLSEL IAYDDNYKDL LLRYFHQMKW GHPKYIEEIV 200
    IDPKNNQRNK FISKVKNPFD KVIGIGSAST KKKSEQLASQ MALTNLGVII 250
    DGEIDTDWIN KIEKIETEAT QTEIKDKKPM SVFNPNNKLL SKNTIKNLLL 300
    QYNTKLPTID IDLKLFYEAM THRSYLIRKN LPNRDVPKSK SIVRLQKKSN 350
    ERLQFLGDAV IHFIIGEYLF NKYADSGEGY LTRLRCKLEN SESLFFLAKQ 400
    SDISSYLLIS QNIEVLHGRE NVNIIGGGLE AFVGALYLNI GLGTVKQFLL 450
    EIMRIELDIN QIAENETNYK DLILQLYNKN KWGHPVYKIL KEEGPDHCKI 500
    FTMGLYLGNK LMGIGKASSK KKAEQIASKK MYQNYINN 538
    Length:538
    Mass (Da):63,058
    Last modified:December 7, 2004 - v1
    Checksum:iBDC3AD6D0CB4E904
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY653733 Genomic DNA. Translation: AAV50612.1.
    RefSeqiYP_003986845.1. NC_014649.1.

    Genome annotation databases

    GeneIDi9924960.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY653733 Genomic DNA. Translation: AAV50612.1 .
    RefSeqi YP_003986845.1. NC_014649.1.

    3D structure databases

    ProteinModelPortali Q5UQT7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 9924960.

    Family and domain databases

    Gene3Di 1.10.1520.10. 2 hits.
    3.30.160.20. 2 hits.
    HAMAPi MF_00104. RNase_III.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR011907. RNase_III.
    IPR000999. RNase_III_dom.
    [Graphical view ]
    PANTHERi PTHR11207. PTHR11207. 1 hit.
    Pfami PF00035. dsrm. 2 hits.
    PF00636. Ribonuclease_3. 2 hits.
    [Graphical view ]
    SMARTi SM00358. DSRM. 2 hits.
    SM00535. RIBOc. 2 hits.
    [Graphical view ]
    SUPFAMi SSF69065. SSF69065. 2 hits.
    PROSITEi PS50137. DS_RBD. 1 hit.
    PS00517. RNASE_3_1. 1 hit.
    PS50142. RNASE_3_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Rowbotham-Bradford.

    Entry informationi

    Entry nameiRNC_MIMIV
    AccessioniPrimary (citable) accession number: Q5UQT7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3