Q5UQS6 (PAP1_MIMIV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative poly(A) polymerase catalytic subunit
EC=2.7.7.19

Gene names

Ordered Locus Names:

MIMI_R341

Organism

Acanthamoeba polyphaga mimivirus (APMV) [Reference proteome]

Taxonomic identifier

212035 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Mimiviridae › Mimivirus

Virus host

Acanthamoeba polyphaga (Amoeba) [TaxID: 5757]

Protein attributes

Sequence length	584 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Polymerase that creates the 3'-poly(A) tail of mRNA's Potential.
Catalytic activity	ATP + RNA(n) = diphosphate + RNA(n+1).
Subcellular location	Virion.
Sequence similarities	Belongs to the poxviridae poly(A) polymerase catalytic subunit family. Highly divergent.

Ontologies

Keywords
Biological process	Transcription mRNA processing
Cellular component	Virion
Ligand	ATP-binding Nucleotide-binding
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mRNA processing Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	virion Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW polynucleotide adenylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 584	584	Putative poly(A) polymerase catalytic subunit		PRO_0000253421

Sequences

	Sequence		Length	Mass (Da)
	Q5UQS6 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: D14A33890DE87406	FASTA	584	68,247
	10 20 30 40 50 60 MLKNKTRAEK YQTYYTTNEY QIVKEKLPDI IRDAEIKASE VLEPTIYEKR AIMEVIKDFI 70 80 90 100 110 120 RDHQRKVYGG TALNEALKQV NPKDAIYDNY SFSDIEFYSP TPVQDLVDLC NILYRKGYKF 130 140 150 160 170 180 VQGKDAQHEE TYSIFVNFQL YCDITYSPTR VFYGIKTIEI DGINYTDPHF MLIDYLRMVN 190 200 210 220 230 240 QPLTAAGQRW EKAFERMYRL LKDYPIEDFD KRLDIPEPPE EIQSYISRIK TEFLSDNKLN 250 260 270 280 290 300 ESFLISGIEA YNFYIRHAAS SKDEEQMART NRNVVNLNNF IANVPFSELI SVNYREDVKN 310 320 330 340 350 360 TYNFLRMIVE DKEKISVDEY FPLFQFTGYS TVIKYDDHPI IRIYEGDGYC IPNVKTVKTV 370 380 390 400 410 420 ENDNGTKTKY EYKYVSFQYV LMILYINKFR AHLDKNKPMY FNYGIAISNL VKARNIYLDQ 430 440 450 460 470 480 TGKSVLDNTV FKEFRTNCTG NTISFTRMNR LRLLEKRKQG KQTSFVYTPE DFFKKDLETQ 490 500 510 520 530 540 AKLDPSKARF KNTSGNKIMV PKYLLFKIDN NGNIEDNIHS EEAEISEKEE TSGGSSISTD 550 560 570 580 KSFEESPNSS PNSSPNNSLN NSIDISTNNY DDRSENSLDS LTSD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The 1.2-megabase genome sequence of Mimivirus." Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H., La Scola B., Susan M., Claverie J.-M. Science 306:1344-1350(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Rowbotham-Bradford.
[2]	Abergel C. Unpublished observations (SEP-2007) Cited for: SIMILARITY.
[3]	"Mimivirus giant particles incorporate a large fraction of anonymous and unique gene products." Renesto P., Abergel C., Decloquement P., Moinier D., Azza S., Ogata H., Fourquet P., Gorvel J.-P., Claverie J.-M., Raoult D. J. Virol. 80:11678-11685(2006) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], SUBCELLULAR LOCATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY653733 Genomic DNA. Translation: AAV50610.1.
RefSeq	YP_003986843.1. NC_014649.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	9924958.
Phylogenomic databases
ProtClustDB	CLSP2510026.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

PAP1_MIMIV

Accession

Primary (citable) accession number: Q5UQS6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	December 7, 2004
Last modified:	July 11, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program