Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Arginine--tRNA ligase

Gene

RARS

Organism
Acanthamoeba polyphaga mimivirus (APMV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei162L-arginineBy similarity1
Binding sitei332L-arginineBy similarity1
Binding sitei336L-arginineBy similarity1
Binding sitei360L-arginineBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:RARS
Ordered Locus Names:MIMI_R663
OrganismiAcanthamoeba polyphaga mimivirus (APMV)
Taxonomic identifieri212035 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
Virus hostiAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]
Proteomesi
  • UP000001134 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516651 – 600Arginine--tRNA ligaseAdd BLAST600

Proteomic databases

PRIDEiQ5UQ59.

Structurei

3D structure databases

ProteinModelPortaliQ5UQ59.
SMRiQ5UQ59.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni151 – 153L-arginine bindingBy similarity3

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi152 – 162"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

OrthoDBiVOG090000CF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5UQ59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQDNLIYLAN CFLNEAIKTT LQNLNKVNII DTPELYSFVK GINTDYQFNK
60 70 80 90 100
STKLANDCNL DKEKIVNELI TQLKSNSFFE NISSVELEQN KSVKINGKKT
110 120 130 140 150
NTVIKQIMIT LNISKLYLSN RINLLYKRIL SGSSIYVPNT ITKKIIVDYS
160 170 180 190 200
SPNIAKEMHI GHLRSTIIGE SICRVLEMCG HDVYRINHVG DWGTQFGMLI
210 220 230 240 250
AYIKNNQIES YTISELMNIY KESRKLFESS IDFKNQSRLE TVSLQNGNIE
260 270 280 290 300
SITIWQKIHK ISMNSFHEIY SLLGINNLIT KGESFYQDQM TELVNSLTSD
310 320 330 340 350
NKITVENDMK LMFVEGISKP FILQKSDGGF TYDTSDLTAL KYRLFIEKAD
360 370 380 390 400
HIIYVVDSSQ QEHFSQMFQI AEKLDWIKNQ QLQHIGFGLV LGSDGSKLKT
410 420 430 440 450
RSGETIKLQD VIDNVVSHAS NITRELIKQK NLDWNDDDIL TISKKIAINC
460 470 480 490 500
IKYSDLNNPR LNNYKFDINK MLNSKGNTAV YLMYGLARCK SILRKVPNNT
510 520 530 540 550
VLNGDIIIEN ENSRNLLLHV LKYVEVIDQT VETMCPHYLC IYLYDLIGSL
560 570 580 590 600
TKFYTTNRCL EYDNDNLIGY NANNLRIVNM VKIIISKIFE LIGLEEIEQL
Length:600
Mass (Da):68,994
Last modified:December 7, 2004 - v1
Checksum:i8B35DBD6794CCE0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY653733 Genomic DNA. Translation: AAV50924.1.
RefSeqiYP_003987185.1. NC_014649.1.

Genome annotation databases

GeneIDi9925309.
KEGGivg:9925309.

Similar proteinsi

Entry informationi

Entry nameiSYR_MIMIV
AccessioniPrimary (citable) accession number: Q5UQ59
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: December 7, 2004
Last modified: September 27, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families