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Q5UP54 (YR596_MIMIV) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable FAD-linked sulfhydryl oxidase R596

EC=1.8.3.2
Gene names
Ordered Locus Names:MIMI_R596
OrganismAcanthamoeba polyphaga mimivirus (APMV) [Reference proteome]
Taxonomic identifier212035 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
Virus hostAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation By similarity.

Catalytic activity

2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.

Cofactor

FAD By similarity.

Subcellular location

Virion.

Sequence similarities

Contains 1 ERV/ALR sulfhydryl oxidase domain.

Ontologies

Keywords
   Cellular componentVirion
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   PTMDisulfide bond
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentvirion

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionthiol oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 292292Probable FAD-linked sulfhydryl oxidase R596
PRO_0000247371

Regions

Domain33 – 139107ERV/ALR sulfhydryl oxidase

Amino acid modifications

Disulfide bond80 ↔ 83Redox-active Potential

Secondary structure

.................................... 292
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q5UP54 [UniParc].

Last modified December 7, 2004. Version 1.
Checksum: 5FEBA7FD1B7F526B

FASTA29233,998
        10         20         30         40         50         60 
MSLSKQVVPT HRVEIAPNSE STCKMDHSNY QHNGLITKIW GTAGWTFNHA VTFGYPLNPT 

        70         80         90        100        110        120 
SDDKRRYKNY FISLGDVLPC RLCRESYKKF ITTGKTALTN EVLRNRHTLT KWFYDVHNAV 

       130        140        150        160        170        180 
NNKLEVDYGL SYEDVVNKYE SFRAKCGKPV PTVKGCVTPL DHKAFSFKKL YYMDAPIVSL 

       190        200        210        220        230        240 
DKVENFVRIA RMRGISDKYF CFLELATVLN GDFNELKKQS SWEYRNKYCQ KKIRHMRENA 

       250        260        270        280        290 
IPSIEEQGYW KGTPTIDELK LLLFLCSNLN RTEVNDAINN VERLESTHYI EN 

« Hide

References

[1]"The 1.2-megabase genome sequence of Mimivirus."
Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H., La Scola B., Susan M., Claverie J.-M.
Science 306:1344-1350(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Rowbotham-Bradford.
[2]"Mimivirus giant particles incorporate a large fraction of anonymous and unique gene products."
Renesto P., Abergel C., Decloquement P., Moinier D., Azza S., Ogata H., Fourquet P., Gorvel J.-P., Claverie J.-M., Raoult D.
J. Virol. 80:11678-11685(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], SUBCELLULAR LOCATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY653733 Genomic DNA. Translation: AAV50859.1.
RefSeqYP_003987112.1. NC_014649.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3GWNX-ray1.78A/B33-145[»]
3TD7X-ray2.21A1-292[»]
ProteinModelPortalQ5UP54.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID9925233.

Family and domain databases

Gene3D1.20.120.310. 1 hit.
InterProIPR017905. ERV/ALR_sulphydryl_oxidase.
[Graphical view]
PfamPF04777. Evr1_Alr. 1 hit.
[Graphical view]
SUPFAMSSF69000. SSF69000. 1 hit.
PROSITEPS51324. ERV_ALR. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ5UP54.

Entry information

Entry nameYR596_MIMIV
AccessionPrimary (citable) accession number: Q5UP54
Entry history
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: December 7, 2004
Last modified: October 16, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references