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Q5UP54

- YR596_MIMIV

UniProt

Q5UP54 - YR596_MIMIV

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Protein
Probable FAD-linked sulfhydryl oxidase R596
Gene
MIMI_R596
Organism
Acanthamoeba polyphaga mimivirus (APMV)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation By similarity.

Catalytic activityi

2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.

Cofactori

FAD By similarity.

GO - Molecular functioni

  1. thiol oxidase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Probable FAD-linked sulfhydryl oxidase R596 (EC:1.8.3.2)
Gene namesi
Ordered Locus Names:MIMI_R596
OrganismiAcanthamoeba polyphaga mimivirus (APMV)
Taxonomic identifieri212035 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
Virus hostiAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]
ProteomesiUP000001134: Genome

Subcellular locationi

GO - Cellular componenti

  1. virion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 292292Probable FAD-linked sulfhydryl oxidase R596
PRO_0000247371Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi80 ↔ 83Redox-active Reviewed prediction

Keywords - PTMi

Disulfide bond

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi37 – 5317
Helixi61 – 7717
Beta strandi78 – 803
Helixi81 – 9010
Helixi94 – 963
Helixi100 – 1034
Helixi106 – 12318
Helixi132 – 1409
Helixi160 – 17112
Helixi180 – 1834
Helixi184 – 1863
Helixi187 – 1926
Helixi197 – 2004
Helixi201 – 2088
Turni209 – 2113
Helixi213 – 2164
Helixi221 – 23818
Turni249 – 2524
Helixi256 – 2627
Turni263 – 2653
Helixi271 – 29020

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3GWNX-ray1.78A/B33-145[»]
3TD7X-ray2.21A1-292[»]
ProteinModelPortaliQ5UP54.

Miscellaneous databases

EvolutionaryTraceiQ5UP54.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini33 – 139107ERV/ALR sulfhydryl oxidase
Add
BLAST

Sequence similaritiesi

Family and domain databases

Gene3Di1.20.120.310. 1 hit.
InterProiIPR017905. ERV/ALR_sulphydryl_oxidase.
[Graphical view]
PfamiPF04777. Evr1_Alr. 1 hit.
[Graphical view]
SUPFAMiSSF69000. SSF69000. 1 hit.
PROSITEiPS51324. ERV_ALR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5UP54-1 [UniParc]FASTAAdd to Basket

« Hide

MSLSKQVVPT HRVEIAPNSE STCKMDHSNY QHNGLITKIW GTAGWTFNHA    50
VTFGYPLNPT SDDKRRYKNY FISLGDVLPC RLCRESYKKF ITTGKTALTN 100
EVLRNRHTLT KWFYDVHNAV NNKLEVDYGL SYEDVVNKYE SFRAKCGKPV 150
PTVKGCVTPL DHKAFSFKKL YYMDAPIVSL DKVENFVRIA RMRGISDKYF 200
CFLELATVLN GDFNELKKQS SWEYRNKYCQ KKIRHMRENA IPSIEEQGYW 250
KGTPTIDELK LLLFLCSNLN RTEVNDAINN VERLESTHYI EN 292
Length:292
Mass (Da):33,998
Last modified:December 7, 2004 - v1
Checksum:i5FEBA7FD1B7F526B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY653733 Genomic DNA. Translation: AAV50859.1.
RefSeqiYP_003987112.1. NC_014649.1.

Genome annotation databases

GeneIDi9925233.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY653733 Genomic DNA. Translation: AAV50859.1 .
RefSeqi YP_003987112.1. NC_014649.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3GWN X-ray 1.78 A/B 33-145 [» ]
3TD7 X-ray 2.21 A 1-292 [» ]
ProteinModelPortali Q5UP54.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9925233.

Miscellaneous databases

EvolutionaryTracei Q5UP54.

Family and domain databases

Gene3Di 1.20.120.310. 1 hit.
InterProi IPR017905. ERV/ALR_sulphydryl_oxidase.
[Graphical view ]
Pfami PF04777. Evr1_Alr. 1 hit.
[Graphical view ]
SUPFAMi SSF69000. SSF69000. 1 hit.
PROSITEi PS51324. ERV_ALR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Rowbotham-Bradford.
  2. "Mimivirus giant particles incorporate a large fraction of anonymous and unique gene products."
    Renesto P., Abergel C., Decloquement P., Moinier D., Azza S., Ogata H., Fourquet P., Gorvel J.-P., Claverie J.-M., Raoult D.
    J. Virol. 80:11678-11685(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], SUBCELLULAR LOCATION.

Entry informationi

Entry nameiYR596_MIMIV
AccessioniPrimary (citable) accession number: Q5UP54
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: December 7, 2004
Last modified: October 16, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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