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Q5UGI6

- Q5UGI6_HUMAN

UniProt

Q5UGI6 - Q5UGI6_HUMAN

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Protein
Submitted name:

Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2

Gene
SERPING1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. serine-type endopeptidase inhibitor activity Source: InterPro

GO - Biological processi

  1. negative regulation of complement activation Source: InterPro
  2. regulation of blood coagulation Source: InterPro
Complete GO annotation...

Protein family/group databases

MEROPSiI04.024.

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2Imported
Gene namesi
Name:SERPING1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ5UGI6.

Structurei

3D structure databases

ProteinModelPortaliQ5UGI6.

Family & Domainsi

Sequence similaritiesi

Belongs to the serpin family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231936.
HOVERGENiHBG104060.

Family and domain databases

InterProiIPR015553. C1-inh.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PTHR11461:SF156. PTHR11461:SF156. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5UGI6-1 [UniParc]FASTAAdd to Basket

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GLQADPADPP AAAAGWGAGE NTKTNLESIL SYPKDFTCVH QALKGFTTKG    50
VTSVSQIFHS PDLAIRDTFV NASRTLYSSS PRVLSNNSDA NLELINTWVA 100
KNTNNKISRL LDSLPSDTRL VLLNAIYLSA KWKTTFDPKK TRMEPFHFKN 150
SVIKVPMMNS KKYPVAHFID QTLKAKVGQL QLSHNLSLVI LVPQNLKHRL 200
EDMEQALSPS VFKAIMEKLE MSKFQPTLLT LPRIKVTTSQ DMLSIMEKLE 250
FFDFSYDLNL CGLTEDPDLQ VSAMLHQTVL ELTETGVEAA AASAISVART 300
LLVFEVQQPF LFVLWDQQHK FPVFMGRVYD PRA 333
Length:333
Mass (Da):37,288
Last modified:December 7, 2004 - v1
Checksum:iC1CB12112A4F5E8F
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY732485 mRNA. Translation: AAV33124.1.
UniGeneiHs.384598.

Genome annotation databases

UCSCiuc001nks.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY732485 mRNA. Translation: AAV33124.1 .
UniGenei Hs.384598.

3D structure databases

ProteinModelPortali Q5UGI6.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I04.024.

Proteomic databases

PRIDEi Q5UGI6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc001nks.1. human.

Phylogenomic databases

HOGENOMi HOG000231936.
HOVERGENi HBG104060.

Miscellaneous databases

ChiTaRSi SERPING1. human.

Family and domain databases

InterProi IPR015553. C1-inh.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view ]
PANTHERi PTHR11461. PTHR11461. 1 hit.
PTHR11461:SF156. PTHR11461:SF156. 1 hit.
Pfami PF00079. Serpin. 1 hit.
[Graphical view ]
SMARTi SM00093. SERPIN. 1 hit.
[Graphical view ]
SUPFAMi SSF56574. SSF56574. 1 hit.
PROSITEi PS00284. SERPIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Novel splicing variants of some human genes."
    Wang P.Z., Wang F., Chang Q.S., Wang X.
    Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ5UGI6_HUMAN
AccessioniPrimary (citable) accession number: Q5UGI6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: September 3, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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