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Q5UGI6

- Q5UGI6_HUMAN

UniProt

Q5UGI6 - Q5UGI6_HUMAN

Protein
Submitted name:

Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2

Gene

SERPING1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. serine-type endopeptidase inhibitor activity Source: InterPro

    GO - Biological processi

    1. negative regulation of complement activation Source: InterPro
    2. regulation of blood coagulation Source: InterPro

    Protein family/group databases

    MEROPSiI04.024.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2Imported
    Gene namesi
    Name:SERPING1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiQ5UGI6.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5UGI6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the serpin family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000231936.
    HOVERGENiHBG104060.

    Family and domain databases

    InterProiIPR015553. C1-inh.
    IPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view]
    PANTHERiPTHR11461. PTHR11461. 1 hit.
    PTHR11461:SF156. PTHR11461:SF156. 1 hit.
    PfamiPF00079. Serpin. 1 hit.
    [Graphical view]
    SMARTiSM00093. SERPIN. 1 hit.
    [Graphical view]
    SUPFAMiSSF56574. SSF56574. 1 hit.
    PROSITEiPS00284. SERPIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q5UGI6-1 [UniParc]FASTAAdd to Basket

    « Hide

    GLQADPADPP AAAAGWGAGE NTKTNLESIL SYPKDFTCVH QALKGFTTKG    50
    VTSVSQIFHS PDLAIRDTFV NASRTLYSSS PRVLSNNSDA NLELINTWVA 100
    KNTNNKISRL LDSLPSDTRL VLLNAIYLSA KWKTTFDPKK TRMEPFHFKN 150
    SVIKVPMMNS KKYPVAHFID QTLKAKVGQL QLSHNLSLVI LVPQNLKHRL 200
    EDMEQALSPS VFKAIMEKLE MSKFQPTLLT LPRIKVTTSQ DMLSIMEKLE 250
    FFDFSYDLNL CGLTEDPDLQ VSAMLHQTVL ELTETGVEAA AASAISVART 300
    LLVFEVQQPF LFVLWDQQHK FPVFMGRVYD PRA 333
    Length:333
    Mass (Da):37,288
    Last modified:December 7, 2004 - v1
    Checksum:iC1CB12112A4F5E8F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY732485 mRNA. Translation: AAV33124.1.
    UniGeneiHs.384598.

    Genome annotation databases

    UCSCiuc001nks.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY732485 mRNA. Translation: AAV33124.1 .
    UniGenei Hs.384598.

    3D structure databases

    ProteinModelPortali Q5UGI6.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi I04.024.

    Proteomic databases

    PRIDEi Q5UGI6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc001nks.1. human.

    Phylogenomic databases

    HOGENOMi HOG000231936.
    HOVERGENi HBG104060.

    Miscellaneous databases

    ChiTaRSi SERPING1. human.

    Family and domain databases

    InterProi IPR015553. C1-inh.
    IPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view ]
    PANTHERi PTHR11461. PTHR11461. 1 hit.
    PTHR11461:SF156. PTHR11461:SF156. 1 hit.
    Pfami PF00079. Serpin. 1 hit.
    [Graphical view ]
    SMARTi SM00093. SERPIN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56574. SSF56574. 1 hit.
    PROSITEi PS00284. SERPIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Novel splicing variants of some human genes."
      Wang P.Z., Wang F., Chang Q.S., Wang X.
      Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ5UGI6_HUMAN
    AccessioniPrimary (citable) accession number: Q5UGI6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 7, 2004
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.