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Protein
Submitted name:

Potassium channel, subfamily K, member 5

Gene

KCNK5

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotationImported

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium channel, subfamily K, member 5Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:KCNK5Imported
OrganismiOryctolagus cuniculus (Rabbit)
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Chromosome 12

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2621HelicalSequence analysisAdd
BLAST
Transmembranei85 – 10420HelicalSequence analysisAdd
BLAST
Transmembranei116 – 13722HelicalSequence analysisAdd
BLAST
Transmembranei158 – 18225HelicalSequence analysisAdd
BLAST
Transmembranei194 – 21320HelicalSequence analysisAdd
BLAST
Transmembranei225 – 24420HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000005731.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini78 – 13760Ion_trans_2InterPro annotationAdd
BLAST
Domaini172 – 24776Ion_trans_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00760000118858.
HOGENOMiHOG000113211.
HOVERGENiHBG052236.
KOiK04916.
OMAiEQLMNEY.
OrthoDBiEOG091G058Z.
TreeFamiTF313947.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR003092. 2pore_dom_K_chnl_TASK.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
PR01095. TASKCHANNEL.

Sequencei

Sequence statusi: Complete.

Q5UE95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDRGPLLTS AIIFYLAIGA AIFEVLEEPH WKEAKKNYYT QKLHLLKEFP
60 70 80 90 100
CLGQEGLDKI LQVVSDASGQ GVAITGNQTF NNWNWPNAMI FAATVITTIG
110 120 130 140 150
YGNVAPKTPA GRLFCVFYGL FGVPLCLTWI SALGKFFGGR AKRLGQFLTR
160 170 180 190 200
RGVSLRKAQI TCTAIFIVWG VLVHLVIPPF VFMVTEEWDY IEGFYYSFIT
210 220 230 240 250
ISTIGFGDFV AGVNPSANYH ALYRYFVELW IYLGLAWLSL FVNWKVSMFV
260 270 280 290 300
EVHKAIKKRR RRRKESFDSS PRSRQALQVA GSTASKDVNI FSFLSKKEET
310 320 330 340 350
YNDLIKQIGK KAMKTSTAGE RGPGPGPQAG GLPALPPSLA PLVVYSKNRV
360 370 380 390 400
PSLEEVSQTL RSKGHVSRPP GGEQDGAQAP EDGSPSSEVF INQLDRISEE
410 420 430 440 450
GEPWDAQDYH PLIFQNANIN FVHEDAGLSD EETSKSSLED NLAVEERPPE
460 470 480 490
GARAEAPLTT AEVPSSDEST FTSTESELSV PYEQLLNEYN KASGPKGT
Length:498
Mass (Da):55,070
Last modified:December 7, 2004 - v1
Checksum:i8D8B8A9D5E86F8E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02017901 Genomic DNA. No translation available.
AY752983 mRNA. Translation: AAV30847.1.
RefSeqiNP_001076174.1. NM_001082705.2.
UniGeneiOcu.3192.

Genome annotation databases

EnsembliENSOCUT00000006633; ENSOCUP00000005731; ENSOCUG00000006633.
GeneIDi100009446.
KEGGiocu:100009446.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02017901 Genomic DNA. No translation available.
AY752983 mRNA. Translation: AAV30847.1.
RefSeqiNP_001076174.1. NM_001082705.2.
UniGeneiOcu.3192.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000005731.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOCUT00000006633; ENSOCUP00000005731; ENSOCUG00000006633.
GeneIDi100009446.
KEGGiocu:100009446.

Organism-specific databases

CTDi8645.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00760000118858.
HOGENOMiHOG000113211.
HOVERGENiHBG052236.
KOiK04916.
OMAiEQLMNEY.
OrthoDBiEOG091G058Z.
TreeFamiTF313947.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR003092. 2pore_dom_K_chnl_TASK.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
PR01095. TASKCHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5UE95_RABIT
AccessioniPrimary (citable) accession number: Q5UE95
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: September 7, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.