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Protein
Submitted name:

MAS-related GPR member D

Gene

Mrgprd

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
MAS-related GPR member DImported
Submitted name:
MAS-related GPR, member DImported
Submitted name:
Mas-related G protein-coupled receptor dImported
Submitted name:
Mas-related G-protein-coupled receptor member DImported
Gene namesi
Name:MrgprdImported
Synonyms:MgrdImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:3033142. Mrgprd.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei24 – 5128HelicalSequence analysisAdd
BLAST
Transmembranei63 – 8321HelicalSequence analysisAdd
BLAST
Transmembranei108 – 13427HelicalSequence analysisAdd
BLAST
Transmembranei146 – 17025HelicalSequence analysisAdd
BLAST
Transmembranei182 – 20524HelicalSequence analysisAdd
BLAST
Transmembranei221 – 24525HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063021.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini43 – 278236G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IWY7. Eukaryota.
ENOG41117F1. LUCA.
HOVERGENiHBG003592.
KOiK08392.
OMAiPSTCTND.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR026232. MRGPCRD.
IPR026234. MRGPCRFAMILY.
[Graphical view]
PANTHERiPTHR11334. PTHR11334. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR02110. MRGPCRD.
PR02108. MRGPCRFAMILY.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5UCB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSTLDSSPA PGLTISPTMD LVTWIYFSVT FLAMATCVGG MAGNSLVIWL
60 70 80 90 100
LSCNGMQRSP FCVYVLNLAV ADFLFLFCMA SMLSLETGPL LIVNISAKIY
110 120 130 140 150
EGMRRIKYFA YTAGLSLLTA ISTQRCLSVL FPIWYKCHRP RHLSSVVSGA
160 170 180 190 200
LWALAFLMNF LASFFCVQFW HPNKHQCFKV DIVFNSLILG IFMPVMILTS
210 220 230 240 250
TILFIRVRKN SLMQRRRPRR LYVVILTSIL VFLTCSLPLG INWFLLYWVD
260 270 280 290 300
VKRDVRLLYS CVSRFSSSLS SSANPVIYFL VGSQKSHRLQ ESLGAVLGRA
310 320
LRDEPEPEGR ETPSTCTNDG V
Length:321
Mass (Da):36,126
Last modified:May 10, 2005 - v1
Checksum:iB0642547A75077B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132081 Genomic DNA. No translation available.
AC225443 Genomic DNA. No translation available.
BC137948 mRNA. Translation: AAI37949.1.
BC137950 mRNA. Translation: AAI37951.1.
AY762266 mRNA. Translation: AAV30216.1.
HG426098 Genomic DNA. Translation: CDG86216.1.
RefSeqiNP_987075.1. NM_203490.3.
UniGeneiMm.370299.

Genome annotation databases

EnsembliENSMUST00000062163; ENSMUSP00000063021; ENSMUSG00000051207.
GeneIDi211578.
KEGGimmu:211578.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132081 Genomic DNA. No translation available.
AC225443 Genomic DNA. No translation available.
BC137948 mRNA. Translation: AAI37949.1.
BC137950 mRNA. Translation: AAI37951.1.
AY762266 mRNA. Translation: AAV30216.1.
HG426098 Genomic DNA. Translation: CDG86216.1.
RefSeqiNP_987075.1. NM_203490.3.
UniGeneiMm.370299.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063021.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000062163; ENSMUSP00000063021; ENSMUSG00000051207.
GeneIDi211578.
KEGGimmu:211578.

Organism-specific databases

CTDi116512.
MGIiMGI:3033142. Mrgprd.

Phylogenomic databases

eggNOGiENOG410IWY7. Eukaryota.
ENOG41117F1. LUCA.
HOVERGENiHBG003592.
KOiK08392.
OMAiPSTCTND.

Miscellaneous databases

NextBioi373293.
SOURCEiSearch...

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR026232. MRGPCRD.
IPR026234. MRGPCRFAMILY.
[Graphical view]
PANTHERiPTHR11334. PTHR11334. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR02110. MRGPCRD.
PR02108. MRGPCRFAMILY.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  2. "Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd."
    Zylka M.J., Rice F.L., Anderson D.J.
    Neuron 45:17-25(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. "Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes."
    Premzl M.
    Gene 540:16-19(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: N/AImported.
  5. Ensembl
    Submitted (AUG-2015) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  6. "Curated eutherian third party data gene data sets."
    Premzl M.
    Data Brief 6:208-213(2016) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: N/AImported.

Entry informationi

Entry nameiQ5UCB4_MOUSE
AccessioniPrimary (citable) accession number: Q5UCB4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 11, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.