Q5U8Z9 (Q5U8Z9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CRISP2 protein EMBL AAI07708.1

Submitted name:
Cysteine-rich secretory protein 2, isoform CRA_a EMBL EAX04340.1
Submitted name:
Testis-specific protein TPX1 b isoform EMBL AAP41200.1
Submitted name:
Testis-specific protein TPX1 d isoform EMBL AAP44114.1
Submitted name:
Testis-specific protein TPX1 e isoform EMBL AAV48552.1

Gene names

Name:	CRISP2 EMBL AAI07708.1
ORF Names:	hCG_21701 EMBL EAX04340.1

Organism

Homo sapiens (Human) EMBL AAV48552.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	243 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5U8Z9 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: C5FE698C449CFAD9	FASTA	243	27,259
	10 20 30 40 50 60 MALLPVLFLV TVLLPSLPAE GKDPAFTALL TTQLQVQREI VNKHNELRKA VSPPASNMLK 70 80 90 100 110 120 MEWSREVTTN AQRWANKCTL QHSDPEDRKT STRCGENLYM SSDPTSWSSA IQSWYDEILD 130 140 150 160 170 180 FVYGVGPKSP NAVVGHYTQL VWYSTYQVGC GIAYCPNQDS LKYYYVCQYC PAGNNMNRKN 190 200 210 220 230 240 TPYQQGTPCA GCPDDCDKGL CTNSCQYQDL LSNCDSLKNT AGCEHELLKE KCKATCLCEN KIY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning of an isoform of TPX1 gene related to spermatogenesis." Lu L., Huang X.Y., Xu M., Xu Z.Y., Zhou Z.M., Li J.M., Sha J.H. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL AAP44114.1.
[2]	"Cloning of an isoform of TPX1 gene related to spermatogenesis." Lu L., Xu M., Huang X.Y., Xu Z.Y., Li J.M., Zhou Z.M., Sha J.H. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL AAP41200.1.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis EMBL AAI07708.1.
[4]	Du Y., Lu L., Xu M., Y L.L., Li J.M., Zhou Z.M., Sha J.H. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL AAV48552.1.
[5]	"Cloning of an isoform of TPX-1 gene related to spermatogenesis." Sha J.H., Zhou Z.M., Li J.M. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL AAV48552.1.
[6]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC107707 mRNA. Translation: AAI07708.1. AY289796 mRNA. Translation: AAP41200.1. AY292863 mRNA. Translation: AAP44114.1. AY773479 mRNA. Translation: AAV48552.1. CH471081 Genomic DNA. Translation: EAX04340.1.
IPI	IPI00029218.
RefSeq	NP_001135879.1. NM_001142407.2. NP_001135880.1. NM_001142408.2. NP_001135889.1. NM_001142417.2. NP_001135907.1. NM_001142435.2. NP_001248751.1. NM_001261822.1. NP_003287.1. NM_003296.3.
UniGene	Hs.2042.
3D structure databases
ProteinModelPortal	Q5U8Z9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5U8Z9.
Proteomic databases
PRIDE	Q5U8Z9.
Protocols and materials databases
DNASU	7180.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7180.
KEGG	hsa:7180.
Organism-specific databases
CTD	7180.
PharmGKB	PA36703.
Phylogenomic databases
HOVERGEN	HBG004184.
Gene expression databases
ArrayExpress	Q5U8Z9.
Bgee	Q5U8Z9.
Family and domain databases
Gene3D	3.40.33.10. 1 hit.
InterPro	IPR001283. Allrgn_V5/Tpx1. IPR018244. Allrgn_V5/Tpx1_CS. IPR014044. CAP_domain. IPR013871. Cysteine_rich_secretory. [Graphical view]
PANTHER	PTHR10334. PTHR10334. 1 hit.
Pfam	PF00188. CAP. 1 hit. PF08562. Crisp. 1 hit. [Graphical view]
PRINTS	PR00837. V5TPXLIKE.
SMART	SM00198. SCP. 1 hit. [Graphical view]
SUPFAM	SSF55797. SCP-like_extracellular. 1 hit.
PROSITE	PS01009. CRISP_1. 1 hit. PS01010. CRISP_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	7180.
NextBio	28148.

Entry information

Entry name

Q5U8Z9_HUMAN

Accession

Primary (citable) accession number: Q5U8Z9

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.