Q5U7D2 (Q5U7D2_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Exostoses (Multiple)-like 3 EMBL AAI62406.1

Submitted name:
Exostoses (multiple)-like 3 Ensembl ENSDARP00000032226 Ensembl ENSDARP00000124029
Submitted name:
Exostosin-like 3 EMBL AAV51343.1

Gene names

Name:	extl3 ZFIN ZDB-GENE-041124-2 Ensembl ENSDARP00000032226 EMBL AAI62406.1 Ensembl ENSDARP00000124029
Synonyms:	Extl3 EMBL AAV51343.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAV51343.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	917 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	anterior/posterior axon guidance Inferred from genetic interaction. Source: ZFIN embryonic pectoral fin morphogenesis Inferred from mutant phenotype. Source: ZFIN heparan sulfate proteoglycan biosynthetic process Inferred from mutant phenotype Ref.1. Source: ZFIN positive regulation of fibroblast growth factor receptor signaling pathway Inferred from mutant phenotype. Source: ZFIN regulation of axon extension Inferred from mutant phenotype Ref.1. Source: ZFIN retinal ganglion cell axon guidance Inferred from mutant phenotype. Source: ZFIN
Cellular component	intrinsic to endoplasmic reticulum membrane Inferred from electronic annotation. Source: InterPro
Molecular function	transferase activity, transferring hexosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5U7D2 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: 8144C0542E59FBD5	FASTA	917	103,853
	10 20 30 40 50 60 MQRNGGIVGN GGQPWVLRRV RLTWLSFMLF FILVFFPLIA HYYLTTIDEA GGPDKRIFGP 70 80 90 100 110 120 RPGGELCEAK HVQDLCRIRE SVSEELLQLE AKRQELNGEI ARLNLRIEAC KRSIDSAKQD 130 140 150 160 170 180 LLQLKNVISQ TEHSYKELMA QNQPKLSLPV RLLPDKDDPG YPPPKSPQSC RLHSCFDYAR 190 200 210 220 230 240 CPLTSGFPVY VYDTGSYPWG EKLDPLVKQA FASSVKSSVY VTDNPNIACL YIALVGEIQE 250 260 270 280 290 300 SPSSPLASPS DLEKQLKALP YWRSDGHNHL LVHLSINSLT QNFLYNVSTG RAAVAQSTFF 310 320 330 340 350 360 ERQYREGFDL VVSPLVHALS EPNFLEVPPQ VPVKRKYLFT FQGEKVESLR SSLLEAPPQS 370 380 390 400 410 420 FEEEMEGDPP ADYDDRIIGT LKAVQDSHLD QVLVEFTCKN QAKPSLPTEW ALCGKREDRL 430 440 450 460 470 480 EVLKVSTFAL VISPGDGQLV ASAGCSMRLF EALEVGAIPV VLGDHSKLPY HHLIRWSEAV 490 500 510 520 530 540 IMVPKPRITE LHFLLRSISD NDLLAMRRQG RFLWETYFST SESIFNTILA SVRTSIQIPA 550 560 570 580 590 600 APIREEPAQE IPHKAGKLAG TDANLADNGD LDLGPVEVEP PYASPRFLRN FTYTAADVYR 610 620 630 640 650 660 TWNRAPGPFH LFPHTPLDPV LPSEAKFLGS GTGFRPIGGG SGGSGKEFQA ALGGNVPREQ 670 680 690 700 710 720 FTVVMLTYER EEVLMNSLER LNGLPYLNKV VVVWNSPKPP SDDLLWPDIG LPIVVVRTGK 730 740 750 760 770 780 NSLNNRFLPW DAIETEAILS IDDDAHLRHD EIMFGFRVWR EARDRIVGFP GRFHAWDLNH 790 800 810 820 830 840 QSWLYNSNYS CELSMVLTGA AFFHKYYAYL YSYVMPRAIR DMVDEYINCE DIAMNFLVSH 850 860 870 880 890 900 ITRKPPIKVT SRWTFRCPGC PQALSHDDSH FHERHKCINF FVKVYGYMPL LYTQFRVDSV 910 LFKTRLPHDK TKCFKFI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer)." Lee J.-S., von der Hardt S., Rusch M.A., Stringer S.E., Stickney H.L., Talbot W.S., Geisler R., Nuesslein-Volhard C., Selleck S.B., Chien C.-B., Roehl H.H. Neuron 44:947-960(2004) [PubMed: 15603738] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pooled EMBL AAI62406.1.
[3]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000032226 Ensembl ENSDARP00000124029.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000032226 Ensembl ENSDARP00000124029.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU896672 Genomic DNA. No translation available. BC162406 mRNA. Translation: AAI62406.1. AY786436 mRNA. Translation: AAV51343.1.
IPI	IPI00483204.
RefSeq	NP_001008402.1. NM_001008402.1.
UniGene	Dr.79599.
3D structure databases
ProteinModelPortal	Q5U7D2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5U7D2.
Protein family/group databases
CAZy	GT47. Glycosyltransferase Family 47. GT64. Glycosyltransferase Family 64.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000039499; ENSDARP00000032226; ENSDARG00000026811. ENSDART00000148892; ENSDARP00000124029; ENSDARG00000026811.
GeneID	493783.
KEGG	dre:493783.
Organism-specific databases
CTD	2137.
ZFIN	ZDB-GENE-041124-2. extl3.
Phylogenomic databases
eggNOG	fiNOG11522.
GeneTree	ENSGT00550000074496.
HOGENOM	HBG381883.
HOVERGEN	HBG051526.
InParanoid	Q5U7D2.
OMA	HDKQKCF.
OrthoDB	EOG415GCN.
PhylomeDB	Q5U7D2.
Gene expression databases
Bgee	Q5U7D2.
Family and domain databases
InterPro	IPR004263. Exostosin. IPR015338. HexNAc_Trfase_a. [Graphical view]
KO	K02370.
Pfam	PF03016. Exostosin. 1 hit. PF09258. Glyco_transf_64. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5U7D2_DANRE

Accession

Primary (citable) accession number: Q5U7D2

Entry history

Integrated into UniProtKB/TrEMBL:	December 7, 2004
Last sequence update:	December 7, 2004
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)