Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Myotubularin-related protein 10-A

Gene

mtmr10-a

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential).Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Myotubularin-related protein 10-A
Gene namesi
Name:mtmr10-a
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-1002521. mtmr10.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002843631 – 765Myotubularin-related protein 10-AAdd BLAST765

Structurei

3D structure databases

ProteinModelPortaliQ5U581.
SMRiQ5U581.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini209 – 650Myotubularin phosphatasePROSITE-ProRule annotationAdd BLAST442

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi197 – 200Poly-Gly4

Sequence similaritiesi

Phylogenomic databases

HOVERGENiHBG108154.
KOiK18085.

Family and domain databases

CDDicd13346. PH-GRAM_MTMR10. 1 hit.
Gene3Di2.30.29.30. 1 hit.
InterProiView protein in InterPro
IPR030573. MTMR10.
IPR036004. MTMR10_PH-GRAM.
IPR022587. MTMR12-like_C.
IPR010569. Myotubularin-like_Pase_dom.
IPR030564. Myotubularin_fam.
IPR011993. PH-like_dom_sf.
IPR029021. Prot-tyrosine_phosphatase-like.
PANTHERiPTHR10807. PTHR10807. 1 hit.
PTHR10807:SF39. PTHR10807:SF39. 1 hit.
PfamiView protein in Pfam
PF12578. 3-PAP. 1 hit.
PF06602. Myotub-related. 2 hits.
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF52799. SSF52799. 2 hits.
PROSITEiView protein in PROSITE
PS51339. PPASE_MYOTUBULARIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5U581-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSLKQPKPS FRSYLLPPQQ EDKLNPETKI KKLKAVLLPG EIVVNEVNFV
60 70 80 90 100
RKCIASDTSQ YDLWGKLICT NFKISFITEN SVPFQRFHYK NLLLGEHDVP
110 120 130 140 150
LTCIEQIVVV NDTKRKQKIL SHNQKLKFNP TELIIYCKDF RILRFRFDEA
160 170 180 190 200
GPESAKKVCL ALAHYSQPTD LQLLFAFEYV AQMYHKPEYK VNGIDPGGGG
210 220 230 240 250
DFCQRTPLFE TYSDWDREIK RTGASDWRVC SVNEGYMIST CLPEYFVVPS
260 270 280 290 300
SLADQDLKQY SHAFVGRRMP LWCWNHSNGS ALVRMASIKD LLQQRKIGQR
310 320 330 340 350
VCSGITRSHP LRSDVYKCDL DHNVPSIQDI QAAFSKLRQL CVNEPFDETE
360 370 380 390 400
EKWLSSLENA QWLEFVRTFL KQAAELAYVL DFSRRSVVLQ EEEGRDVSCL
410 420 430 440 450
VASLVQLMLD PYFRTIVGFQ SLIQKEWVMS AYPFLDRCNH LKRSEKESPL
460 470 480 490 500
FVLFLDCVWQ LLQQYPAAFQ FTETYLTVLH DSTRISLFGT FLFNSPHQRV
510 520 530 540 550
QQSTEFAIAR NIQLGEEKGL KFPSVWDWSL QFSAKDRALF NNPLYIGKSV
560 570 580 590 600
PCVQNGAVKS FKRTKNYSST MRGMPPSVKN GMAIQQDFMP RRNSLILKLK
610 620 630 640 650
PEILQQVPVI IPSSGFEQYL RDWFTKPADL HGVILPCLHG THIKLWKLCY
660 670 680 690 700
LRWTPEAQIN HGGFITAFHK ISLLASEIEL LQSRLRQYRA YPLSTVTSPV
710 720 730 740 750
GEQNRMFFRP DELHSSNGSL DILTSSFPFS PIGNLCRRSI LGTPLSKFIN
760
GAKIWLSTET LANED
Length:765
Mass (Da):88,113
Last modified:December 7, 2004 - v1
Checksum:i89E4B64712513599
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC084803 mRNA. Translation: AAH84803.1.
RefSeqiNP_001088476.1. NM_001095007.1.
UniGeneiXl.49502.

Genome annotation databases

GeneIDi495341.
KEGGixla:495341.

Similar proteinsi

Entry informationi

Entry nameiMTRAA_XENLA
AccessioniPrimary (citable) accession number: Q5U581
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 7, 2004
Last modified: November 22, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families