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Q5U581

- MTRAA_XENLA

UniProt

Q5U581 - MTRAA_XENLA

Protein

Myotubularin-related protein 10-A

Gene

mtmr10-a

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase Potential.Curated

    GO - Molecular functioni

    1. phosphatase activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Myotubularin-related protein 10-A
    Gene namesi
    Name:mtmr10-a
    OrganismiXenopus laevis (African clawed frog)
    Taxonomic identifieri8355 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

    Organism-specific databases

    XenbaseiXB-GENE-1002521. mtmr10.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 765765Myotubularin-related protein 10-APRO_0000284363Add
    BLAST

    Proteomic databases

    PRIDEiQ5U581.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5U581.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini209 – 650442Myotubularin phosphatasePROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi197 – 2004Poly-Gly

    Sequence similaritiesi

    Contains 1 myotubularin phosphatase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    HOVERGENiHBG108154.
    KOiK18085.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    InterProiIPR010569. Myotubularin-like_Pase_dom.
    IPR022587. Myotubularin_assoc.
    IPR011993. PH_like_dom.
    IPR029021. Prot-tyrosine_phosphatase-like.
    [Graphical view]
    PfamiPF12578. 3-PAP. 1 hit.
    PF06602. Myotub-related. 2 hits.
    [Graphical view]
    SUPFAMiSSF52799. SSF52799. 2 hits.
    PROSITEiPS51339. PPASE_MYOTUBULARIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5U581-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFSLKQPKPS FRSYLLPPQQ EDKLNPETKI KKLKAVLLPG EIVVNEVNFV    50
    RKCIASDTSQ YDLWGKLICT NFKISFITEN SVPFQRFHYK NLLLGEHDVP 100
    LTCIEQIVVV NDTKRKQKIL SHNQKLKFNP TELIIYCKDF RILRFRFDEA 150
    GPESAKKVCL ALAHYSQPTD LQLLFAFEYV AQMYHKPEYK VNGIDPGGGG 200
    DFCQRTPLFE TYSDWDREIK RTGASDWRVC SVNEGYMIST CLPEYFVVPS 250
    SLADQDLKQY SHAFVGRRMP LWCWNHSNGS ALVRMASIKD LLQQRKIGQR 300
    VCSGITRSHP LRSDVYKCDL DHNVPSIQDI QAAFSKLRQL CVNEPFDETE 350
    EKWLSSLENA QWLEFVRTFL KQAAELAYVL DFSRRSVVLQ EEEGRDVSCL 400
    VASLVQLMLD PYFRTIVGFQ SLIQKEWVMS AYPFLDRCNH LKRSEKESPL 450
    FVLFLDCVWQ LLQQYPAAFQ FTETYLTVLH DSTRISLFGT FLFNSPHQRV 500
    QQSTEFAIAR NIQLGEEKGL KFPSVWDWSL QFSAKDRALF NNPLYIGKSV 550
    PCVQNGAVKS FKRTKNYSST MRGMPPSVKN GMAIQQDFMP RRNSLILKLK 600
    PEILQQVPVI IPSSGFEQYL RDWFTKPADL HGVILPCLHG THIKLWKLCY 650
    LRWTPEAQIN HGGFITAFHK ISLLASEIEL LQSRLRQYRA YPLSTVTSPV 700
    GEQNRMFFRP DELHSSNGSL DILTSSFPFS PIGNLCRRSI LGTPLSKFIN 750
    GAKIWLSTET LANED 765
    Length:765
    Mass (Da):88,113
    Last modified:December 7, 2004 - v1
    Checksum:i89E4B64712513599
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC084803 mRNA. Translation: AAH84803.1.
    RefSeqiNP_001088476.1. NM_001095007.1.
    UniGeneiXl.49502.

    Genome annotation databases

    GeneIDi495341.
    KEGGixla:495341.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC084803 mRNA. Translation: AAH84803.1 .
    RefSeqi NP_001088476.1. NM_001095007.1.
    UniGenei Xl.49502.

    3D structure databases

    ProteinModelPortali Q5U581.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5U581.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 495341.
    KEGGi xla:495341.

    Organism-specific databases

    CTDi 495341.
    Xenbasei XB-GENE-1002521. mtmr10.

    Phylogenomic databases

    HOVERGENi HBG108154.
    KOi K18085.

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    InterProi IPR010569. Myotubularin-like_Pase_dom.
    IPR022587. Myotubularin_assoc.
    IPR011993. PH_like_dom.
    IPR029021. Prot-tyrosine_phosphatase-like.
    [Graphical view ]
    Pfami PF12578. 3-PAP. 1 hit.
    PF06602. Myotub-related. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52799. SSF52799. 2 hits.
    PROSITEi PS51339. PPASE_MYOTUBULARIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Eye.

    Entry informationi

    Entry nameiMTRAA_XENLA
    AccessioniPrimary (citable) accession number: Q5U581
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 17, 2007
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3