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Q5U581 (MTRAA_XENLA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Myotubularin-related protein 10-A
Gene names
Name:mtmr10-a
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Protein attributes

Sequence length765 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase Potential.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

Contains 1 myotubularin phosphatase domain.

Ontologies

Gene Ontology (GO)
   Molecular_functionphosphatase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 765765Myotubularin-related protein 10-A
PRO_0000284363

Regions

Domain209 – 650442Myotubularin phosphatase
Compositional bias197 – 2004Poly-Gly

Sequences

Sequence LengthMass (Da)Tools
Q5U581 [UniParc].

Last modified December 7, 2004. Version 1.
Checksum: 89E4B64712513599

FASTA76588,113
        10         20         30         40         50         60 
MFSLKQPKPS FRSYLLPPQQ EDKLNPETKI KKLKAVLLPG EIVVNEVNFV RKCIASDTSQ 

        70         80         90        100        110        120 
YDLWGKLICT NFKISFITEN SVPFQRFHYK NLLLGEHDVP LTCIEQIVVV NDTKRKQKIL 

       130        140        150        160        170        180 
SHNQKLKFNP TELIIYCKDF RILRFRFDEA GPESAKKVCL ALAHYSQPTD LQLLFAFEYV 

       190        200        210        220        230        240 
AQMYHKPEYK VNGIDPGGGG DFCQRTPLFE TYSDWDREIK RTGASDWRVC SVNEGYMIST 

       250        260        270        280        290        300 
CLPEYFVVPS SLADQDLKQY SHAFVGRRMP LWCWNHSNGS ALVRMASIKD LLQQRKIGQR 

       310        320        330        340        350        360 
VCSGITRSHP LRSDVYKCDL DHNVPSIQDI QAAFSKLRQL CVNEPFDETE EKWLSSLENA 

       370        380        390        400        410        420 
QWLEFVRTFL KQAAELAYVL DFSRRSVVLQ EEEGRDVSCL VASLVQLMLD PYFRTIVGFQ 

       430        440        450        460        470        480 
SLIQKEWVMS AYPFLDRCNH LKRSEKESPL FVLFLDCVWQ LLQQYPAAFQ FTETYLTVLH 

       490        500        510        520        530        540 
DSTRISLFGT FLFNSPHQRV QQSTEFAIAR NIQLGEEKGL KFPSVWDWSL QFSAKDRALF 

       550        560        570        580        590        600 
NNPLYIGKSV PCVQNGAVKS FKRTKNYSST MRGMPPSVKN GMAIQQDFMP RRNSLILKLK 

       610        620        630        640        650        660 
PEILQQVPVI IPSSGFEQYL RDWFTKPADL HGVILPCLHG THIKLWKLCY LRWTPEAQIN 

       670        680        690        700        710        720 
HGGFITAFHK ISLLASEIEL LQSRLRQYRA YPLSTVTSPV GEQNRMFFRP DELHSSNGSL 

       730        740        750        760 
DILTSSFPFS PIGNLCRRSI LGTPLSKFIN GAKIWLSTET LANED 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Eye.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC084803 mRNA. Translation: AAH84803.1.
RefSeqNP_001088476.1. NM_001095007.1.
UniGeneXl.49502.

3D structure databases

ProteinModelPortalQ5U581.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ5U581.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID495341.
KEGGxla:495341.

Organism-specific databases

CTD495341.
XenbaseXB-GENE-1002521. mtmr10.

Phylogenomic databases

HOVERGENHBG108154.
KOK18085.

Family and domain databases

Gene3D2.30.29.30. 1 hit.
InterProIPR010569. Myotubularin-like_Pase_dom.
IPR022587. Myotubularin_assoc.
IPR011993. PH_like_dom.
IPR029021. Prot-tyrosine_phosphatase-like.
[Graphical view]
PfamPF12578. 3-PAP. 1 hit.
PF06602. Myotub-related. 2 hits.
[Graphical view]
SUPFAMSSF52799. SSF52799. 2 hits.
PROSITEPS51339. PPASE_MYOTUBULARIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTRAA_XENLA
AccessionPrimary (citable) accession number: Q5U581
Entry history
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 7, 2004
Last modified: June 11, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families