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Q5U458

- DJC11_MOUSE

UniProt

Q5U458 - DJC11_MOUSE

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Protein

DnaJ homolog subfamily C member 11

Gene

Dnajc11

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily C member 11
Gene namesi
Name:Dnajc11
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:2443386. Dnajc11.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: Ensembl
  2. mitochondrial inner membrane Source: MGI
  3. mitochondrion Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 559558DnaJ homolog subfamily C member 11PRO_0000247158Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ5U458.
PaxDbiQ5U458.
PRIDEiQ5U458.

PTM databases

PhosphoSiteiQ5U458.

Expressioni

Gene expression databases

BgeeiQ5U458.
CleanExiMM_DNAJC11.
ExpressionAtlasiQ5U458. baseline and differential.
GenevestigatoriQ5U458.

Interactioni

Protein-protein interaction databases

IntActiQ5U458. 2 interactions.
MINTiMINT-4114586.

Structurei

3D structure databases

ProteinModelPortaliQ5U458.
SMRiQ5U458. Positions 14-82.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 8269JPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili415 – 45743Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the DNAJC11 family.Curated
Contains 1 J domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiCOG0484.
GeneTreeiENSGT00760000118947.
HOGENOMiHOG000231113.
HOVERGENiHBG080125.
InParanoidiQ5U458.
KOiK09531.
OMAiFYLAIQR.
OrthoDBiEOG70GMFJ.
TreeFamiTF105170.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR024586. DnaJ-like_C11_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
PF11875. DUF3395. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5U458-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATALSEEEL DNEDYYSLLN VRREASSEEL KAAYRRLCML YHPDKHRDPE
60 70 80 90 100
LKSQAERLFN LVHQAYEVLS DPQTRAIYDI YGKRGLEMEG WEVVERKRTP
110 120 130 140 150
AEIREEFERL QREREERRLQ QRTNPKGTIS VGVDATDLFD RYDEEYEDVS
160 170 180 190 200
GSGFPQIEIN KMHISQSIEA PLTATDTAIL SGSLSTQNGN GGGSVNFALR
210 220 230 240 250
RVTSAKGWGE LEFGAGDLQG PLFGLKLFRN LTPRCFVTTN CALQFSSRGI
260 270 280 290 300
RPGLTTVLAR NLDKNTVGYL QWRWGIQSAM NTSIVRDTKT CHFTVALQLG
310 320 330 340 350
IPHSFALISY QHKFQDDDQT RVKGSLKAGF FGTIVEYGAE RKISRHSVLG
360 370 380 390 400
AAVSIGVPQG VSLKVKLNRA SQTYFFPIHL TDQLLPSAVF YATVGPLVVY
410 420 430 440 450
LAVHRLIIRP YLRAQKEKEL EKQRENTASD ILQKKQEAEA AVRLMQESVR
460 470 480 490 500
RIIEAEESRM GLIIVNAWYG KFVNDKSRKN EKVKVIDVTV PLQCLVKDSK
510 520 530 540 550
LILTEASKAG LPGFYDPCVG EEKSLRVLYQ FRGVLHQVMV PDSEALRIPK

QSHRIDTDG
Length:559
Mass (Da):63,233
Last modified:July 27, 2011 - v2
Checksum:iDA6B7590EC7D2561
GO

Sequence cautioni

The sequence BAC41027.1 differs from that shown. Reason: Probable cloning artifact.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti195 – 1951V → I in BAC41027. (PubMed:16141072)Curated
Sequence conflicti195 – 1951V → I in BAE42661. (PubMed:16141072)Curated
Sequence conflicti195 – 1951V → I in BAE43060. (PubMed:16141072)Curated
Sequence conflicti195 – 1951V → I in AAH85257. (PubMed:15489334)Curated
Sequence conflicti256 – 2561T → S in BAC41027. (PubMed:16141072)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK053156 mRNA. Translation: BAC35287.1.
AK077544 mRNA. Translation: BAC36856.1.
AK089983 mRNA. Translation: BAC41027.1. Sequence problems.
AK171781 mRNA. Translation: BAE42661.1.
AK172542 mRNA. Translation: BAE43060.1.
AL611931 Genomic DNA. Translation: CAM25057.1.
BC085257 mRNA. Translation: AAH85257.1.
CCDSiCCDS18981.2.
RefSeqiNP_766292.2. NM_172704.3.
UniGeneiMm.21353.

Genome annotation databases

EnsembliENSMUST00000062904; ENSMUSP00000051643; ENSMUSG00000039768.
GeneIDi230935.
KEGGimmu:230935.
UCSCiuc008vys.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK053156 mRNA. Translation: BAC35287.1 .
AK077544 mRNA. Translation: BAC36856.1 .
AK089983 mRNA. Translation: BAC41027.1 . Sequence problems.
AK171781 mRNA. Translation: BAE42661.1 .
AK172542 mRNA. Translation: BAE43060.1 .
AL611931 Genomic DNA. Translation: CAM25057.1 .
BC085257 mRNA. Translation: AAH85257.1 .
CCDSi CCDS18981.2.
RefSeqi NP_766292.2. NM_172704.3.
UniGenei Mm.21353.

3D structure databases

ProteinModelPortali Q5U458.
SMRi Q5U458. Positions 14-82.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q5U458. 2 interactions.
MINTi MINT-4114586.

PTM databases

PhosphoSitei Q5U458.

Proteomic databases

MaxQBi Q5U458.
PaxDbi Q5U458.
PRIDEi Q5U458.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000062904 ; ENSMUSP00000051643 ; ENSMUSG00000039768 .
GeneIDi 230935.
KEGGi mmu:230935.
UCSCi uc008vys.2. mouse.

Organism-specific databases

CTDi 55735.
MGIi MGI:2443386. Dnajc11.

Phylogenomic databases

eggNOGi COG0484.
GeneTreei ENSGT00760000118947.
HOGENOMi HOG000231113.
HOVERGENi HBG080125.
InParanoidi Q5U458.
KOi K09531.
OMAi FYLAIQR.
OrthoDBi EOG70GMFJ.
TreeFami TF105170.

Miscellaneous databases

NextBioi 380306.
PROi Q5U458.
SOURCEi Search...

Gene expression databases

Bgeei Q5U458.
CleanExi MM_DNAJC11.
ExpressionAtlasi Q5U458. baseline and differential.
Genevestigatori Q5U458.

Family and domain databases

Gene3Di 1.10.287.110. 1 hit.
InterProi IPR024586. DnaJ-like_C11_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
[Graphical view ]
Pfami PF00226. DnaJ. 1 hit.
PF11875. DUF3395. 1 hit.
[Graphical view ]
PRINTSi PR00625. JDOMAIN.
SMARTi SM00271. DnaJ. 1 hit.
[Graphical view ]
SUPFAMi SSF46565. SSF46565. 1 hit.
PROSITEi PS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
    Tissue: Embryo, Lung and Spleen.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Mammary tumor.

Entry informationi

Entry nameiDJC11_MOUSE
AccessioniPrimary (citable) accession number: Q5U458
Secondary accession number(s): A2A8C9
, Q8BP83, Q8C1Z4, Q8C6U5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 27, 2011
Last modified: November 26, 2014
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3