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Q5U3N5

- PPTC7_DANRE

UniProt

Q5U3N5 - PPTC7_DANRE

Protein

Protein phosphatase PTC7 homolog

Gene

pptc7

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Magnesium or manganese.Curated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi71 – 711Manganese 1By similarity
    Metal bindingi71 – 711Manganese 2By similarity
    Metal bindingi72 – 721Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi216 – 2161Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein phosphatase PTC7 homolog (EC:3.1.3.16)
    Gene namesi
    Name:pptc7
    ORF Names:zgc:101865
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Unplaced

    Organism-specific databases

    ZFINiZDB-GENE-041114-74. pptc7a.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 297297Protein phosphatase PTC7 homologPRO_0000328747Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ5U3N5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini31 – 290260PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000239282.
    HOVERGENiHBG060636.
    InParanoidiQ5U3N5.
    KOiK17508.
    PhylomeDBiQ5U3N5.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    [Graphical view]
    PfamiPF07228. SpoIIE. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5U3N5-1 [UniParc]FASTAAdd to Basket

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    MLSVLSYGRL VARAVIGGLS QTDSRDYSLV SASFGFGKDF RKGILKKGMC    50
    YGDDACFIAR HRSADVLGVA DGVGGWRDYG VDPSQFSGTL MRTCERLVKE 100
    GRFVPSNPVG ILTTSYYELL QNKVPLLGSS TACIVVLDRQ SHRLHTANLG 150
    DSGFLVVRGG EVVHRSDEQQ HYFNTPFQLS IAPPEAEGSV LSDSPDAADS 200
    SSFDVQLGDI ILTATDGLFD NMPDYMILQE LKKLKNTNYE STQQTAKSIA 250
    EQAHVLAYDP NYMSPFAQFA CDNGLNVRGG KPDDITVLLS IVAEYTD 297
    Length:297
    Mass (Da):32,343
    Last modified:December 7, 2004 - v1
    Checksum:iCFBE68867FF6E238
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC085459 mRNA. Translation: AAH85459.1.
    RefSeqiNP_001007379.1. NM_001007378.1.
    UniGeneiDr.37361.

    Genome annotation databases

    GeneIDi492506.
    KEGGidre:492506.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC085459 mRNA. Translation: AAH85459.1 .
    RefSeqi NP_001007379.1. NM_001007378.1.
    UniGenei Dr.37361.

    3D structure databases

    ProteinModelPortali Q5U3N5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 492506.
    KEGGi dre:492506.

    Organism-specific databases

    CTDi 492506.
    ZFINi ZDB-GENE-041114-74. pptc7a.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000239282.
    HOVERGENi HBG060636.
    InParanoidi Q5U3N5.
    KOi K17508.
    PhylomeDBi Q5U3N5.

    Miscellaneous databases

    NextBioi 20865065.
    PROi Q5U3N5.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    [Graphical view ]
    Pfami PF07228. SpoIIE. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Larva.

    Entry informationi

    Entry nameiPPTC7_DANRE
    AccessioniPrimary (citable) accession number: Q5U3N5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3