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Protein
Submitted name:

SH3 domain-binding protein 2

Gene

Sh3bp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
SH3 domain-binding protein 2Imported
Submitted name:
SH3-domain binding protein 2, isoform CRA_aImported
Submitted name:
Sh3bp2 proteinImported
Gene namesi
Name:Sh3bp2Imported
ORF Names:mCG_16341Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1346349. Sh3bp2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000054520.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112554.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini26 – 130105PHInterPro annotationAdd
BLAST
Domaini455 – 55399SH2InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation
Contains SH2 domain.SAAS annotation

Keywords - Domaini

SH2 domainSAAS annotation

Phylogenomic databases

eggNOGiENOG410IGI1. Eukaryota.
ENOG4111SD6. LUCA.
GeneTreeiENSGT00390000002216.
HOVERGENiHBG000016.
KOiK07984.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
3.30.505.10. 1 hit.
InterProiIPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR000980. SH2.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00017. SH2. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00252. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS50001. SH2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5U3L0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAEEMQWPV PMKAIGAQNL LTMPGGVAKA GYLHKKGGTQ LQLLKWPLRF
60 70 80 90 100
VIIHKRCIYY FKSSTSASPQ GAFSLSGYNR VMRAAEETTS NNVFPFKIIH
110 120 130 140 150
ISKKHRTWFF SASSEDERKS WMALLRREIG HFHEKKELPL DTSDSSSDTD
160 170 180 190 200
SFYGAVERPI DISLSSYPMD NEDYEHEDED DSYLEPDSPG PMKLEDALTY
210 220 230 240 250
PPAYPPPPVP VPRKPAFSDL PRAHSFTSKS PSPLLPPPPP KRGLPDTGSA
260 270 280 290 300
PEDAKDALGL RRVEPGLRVP ATPRRMSDPP MSNVPTVPNL RKHPCFRDSV
310 320 330 340 350
NPGLEPWTPG HGTSSVSSST TMAVATSRNC DKLKSFHLSS RGPPTSEPPP
360 370 380 390 400
VPANKPKFLK IAEEPSPREA AKFAPVPPVA PRPPVQKMPM PEATVRPAVL
410 420 430 440 450
PRPENTPLPH LQRSPPDGQS FRGFSFEKAR QPSQADTGEE DSDEDYEKVP
460 470 480 490 500
LPNSVFVNTT ESCEVERLFK ATDPRGEPQD GLYCIRNSST KSGKVLVVWD
510 520 530 540 550
ESSNKVRNYR IFEKDSKFYL EGEVLFASVG SMVEHYHTHV LPSHQSLLLR

HPYGYAGPR
Length:559
Mass (Da):62,188
Last modified:December 7, 2004 - v1
Checksum:i62235DDE3A849E79
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC115695 Genomic DNA. No translation available.
BC085497 mRNA. Translation: AAH85497.1.
AK155898 mRNA. Translation: BAE33490.1.
CH466524 Genomic DNA. Translation: EDL37456.1.
RefSeqiNP_001139330.1. NM_001145858.1.
NP_001139331.1. NM_001145859.1.
NP_036023.3. NM_011893.3.
XP_006504017.1. XM_006503954.1.
XP_006504018.1. XM_006503955.1.
UniGeneiMm.5012.

Genome annotation databases

EnsembliENSMUST00000067638; ENSMUSP00000070890; ENSMUSG00000054520.
ENSMUST00000179943; ENSMUSP00000136671; ENSMUSG00000054520.
GeneIDi24055.
KEGGimmu:24055.
UCSCiuc008xcl.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC115695 Genomic DNA. No translation available.
BC085497 mRNA. Translation: AAH85497.1.
AK155898 mRNA. Translation: BAE33490.1.
CH466524 Genomic DNA. Translation: EDL37456.1.
RefSeqiNP_001139330.1. NM_001145858.1.
NP_001139331.1. NM_001145859.1.
NP_036023.3. NM_011893.3.
XP_006504017.1. XM_006503954.1.
XP_006504018.1. XM_006503955.1.
UniGeneiMm.5012.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112554.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000067638; ENSMUSP00000070890; ENSMUSG00000054520.
ENSMUST00000179943; ENSMUSP00000136671; ENSMUSG00000054520.
GeneIDi24055.
KEGGimmu:24055.
UCSCiuc008xcl.2. mouse.

Organism-specific databases

CTDi6452.
MGIiMGI:1346349. Sh3bp2.

Phylogenomic databases

eggNOGiENOG410IGI1. Eukaryota.
ENOG4111SD6. LUCA.
GeneTreeiENSGT00390000002216.
HOVERGENiHBG000016.
KOiK07984.

Miscellaneous databases

ChiTaRSiSh3bp2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000054520.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
3.30.505.10. 1 hit.
InterProiIPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR000980. SH2.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00017. SH2. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00252. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS50001. SH2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5U3L0_MOUSE
AccessioniPrimary (citable) accession number: Q5U3L0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: September 7, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.