Q5U395 (CNEPA_DANRE) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 54.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: CTD nuclear envelope phosphatase 1A EC=3.1.3.16 Alternative name(s): Serine/threonine-protein phosphatase dullard-A | ||||
| Gene names |
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| Organism | Danio rerio (Zebrafish) (Brachydanio rerio) | ||||
| Taxonomic identifier | 7955 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio |
Protein attributes
| Sequence length | 245 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Serine/threonine phosphatase which may be required for proper nuclear membrane morphology. May antagonize BMP signaling By similarity. |
| Catalytic activity | A phosphoprotein + H2O = a protein + phosphate. |
| Subcellular location | Endoplasmic reticulum membrane; Single-pass membrane protein By similarity. Nucleus membrane; Single-pass membrane protein By similarity. |
| Sequence similarities | Belongs to the dullard family. Contains 1 FCP1 homology domain. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Endoplasmic reticulum Membrane Nucleus |
| Domain | Transmembrane Transmembrane helix |
| Molecular function | Hydrolase Protein phosphatase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | nuclear envelope organization Inferred from sequence or structural similarity. Source: UniProtKB |
| Cellular component | endoplasmic reticulum membrane Inferred from sequence or structural similarity. Source: UniProtKB integral to membraneInferred from electronic annotation. Source: UniProtKB-KW nuclear membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | protein serine/threonine phosphatase activity Inferred from sequence or structural similarity. Source: UniProtKB |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | NIH - Zebrafish Gene Collection (ZGC) project Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BC085649 mRNA. Translation: AAH85649.1. |
| IPI | IPI00512264. |
| RefSeq | NP_001007310.1. NM_001007309.1. |
| UniGene | Dr.78429. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1TA0 based on UniProtKB Q9GZU7. |
| ProteinModelPortal | Q5U395. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q5U395. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENSDART00000029889; ENSDARP00000036009; ENSDARG00000016519. |
| GeneID | 492343. |
| KEGG | dre:492343. |
| NMPDR | fig|7955.3.peg.18884. |
Organism-specific databases | |
| CTD | 492343. |
| ZFIN | ZDB-GENE-041114-177. dullard. |
Phylogenomic databases | |
| eggNOG | fiNOG13204. |
| GeneTree | ENSGT00550000075053. |
| HOGENOM | HBG603876. |
| HOVERGEN | HBG098153. |
| InParanoid | Q5U395. |
| OMA | SRNRLGQ. |
| OrthoDB | EOG4J6RRP. |
| PhylomeDB | Q5U395. |
Gene expression databases | |
| ArrayExpress | Q5U395. |
| Bgee | Q5U395. |
Family and domain databases | |
| InterPro | IPR011948. Dullard_phosphatase. IPR023214. HAD-like_dom. IPR004274. NIF. [Graphical view] |
| Gene3D | G3DSA:3.40.50.1000. HAD-like_dom. 1 hit. |
| KO | K01090. |
| Pfam | PF03031. NIF. 1 hit. [Graphical view] |
| SMART | SM00577. CPDc. 1 hit. [Graphical view] |
| SUPFAM | SSF56784. HAD-like_dom. 1 hit. |
| TIGRFAMs | TIGR02251. HIF-SF_euk. 1 hit. |
| PROSITE | PS50969. FCP1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | CNEPA_DANRE | ||||||||
| Accession | Primary (citable) accession number: Q5U395 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with