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Protein

Battenin

Gene

cln3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • arginine transport Source: GO_Central
  • axonogenesis Source: ZFIN
  • lysosome organization Source: ZFIN
  • negative regulation of neuron apoptotic process Source: ZFIN
  • regulation of intracellular pH Source: GO_Central
  • vacuolar transport Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
BatteninUniRule annotation
Gene namesi
Name:cln3Imported
Synonyms:zgc:92244Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 3

Organism-specific databases

ZFINiZDB-GENE-041114-174 cln3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 46HelicalUniRule annotationAdd BLAST21
Transmembranei89 – 110HelicalUniRule annotationAdd BLAST22
Transmembranei117 – 137HelicalUniRule annotationAdd BLAST21
Transmembranei143 – 167HelicalUniRule annotationAdd BLAST25
Transmembranei179 – 198HelicalUniRule annotationAdd BLAST20
Transmembranei204 – 224HelicalUniRule annotationAdd BLAST21
Transmembranei290 – 308HelicalUniRule annotationAdd BLAST19
Transmembranei328 – 347HelicalUniRule annotationAdd BLAST20
Transmembranei354 – 374HelicalUniRule annotationAdd BLAST21
Transmembranei380 – 404HelicalUniRule annotationAdd BLAST25
Transmembranei416 – 437HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSDARG00000037865

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000055169

Family & Domainsi

Sequence similaritiesi

Belongs to the battenin family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG3880 Eukaryota
ENOG410XT4Z LUCA
GeneTreeiENSGT00390000003249
HOGENOMiHOG000164765
HOVERGENiHBG017297
KOiK12389
OMAiIMLIFPA
OrthoDBiEOG091G07YG
TreeFamiTF314055

Family and domain databases

InterProiView protein in InterPro
IPR003492 Battenin_disease_Cln3
IPR018460 Battenin_disease_Cln3_subgr
IPR036259 MFS_trans_sf
PANTHERiPTHR10981 PTHR10981, 1 hit
PfamiView protein in Pfam
PF02487 CLN3, 1 hit
PIRSFiPIRSF015974 CLN3_BTN1, 1 hit
PRINTSiPR01315 BATTENIN
SUPFAMiSSF103473 SSF103473, 3 hits

Sequencei

Sequence statusi: Complete.

Q5U392-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRSVNSGTA STSDTEGRCQ RWRNCVAFWL LGLCNNFAYV VMLSAAHDIL
60 70 80 90 100
QKQESQNTTA PSPAPNGTNI EFRNSSNSSR YDCNPVSTAA VLLADILPTL
110 120 130 140 150
LIKLTAPFYI HKVPYGFRVL VCFFTAVVSF LMVSFSSTIS MSIIGVIFAS
160 170 180 190 200
VSSGLGELSF LSLSVFFSSD VLSGWGSGTG AAGVAGALLY SALTQAGLTP
210 220 230 240 250
QVTLWIMLVV PVILAVSYFV LLVFPHSFPQ WRCPEVSQSL SRGLNSEERR
260 270 280 290 300
ALIEEDTDTD EDSEPALEDQ DDKHIGPLTF TEKKYIIKGL LKFIFPLALV
310 320 330 340 350
YFAEYFINQG LMELLYFPDS RLSHAEQYRW YQTVYQIGVF VSRTSLFCFK
360 370 380 390 400
IRKIFLMSLL QCANAVLLVF AVYYQFLPNI SVVFVIIAFE GLLGGAAYVN
410 420 430 440
TFFFIREESV EREREFAMAT ATVGDSLGIA FSAAAAFPVH HYFCSL
Length:446
Mass (Da):49,431
Last modified:December 7, 2004 - v1
Checksum:i13780ACB55FB2488
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537342 Genomic DNA No translation available.
BC085653 mRNA Translation: AAH85653.1
RefSeqiNP_001007307.1, NM_001007306.1
UniGeneiDr.79095

Genome annotation databases

EnsembliENSDART00000055170; ENSDARP00000055169; ENSDARG00000037865
GeneIDi492340
KEGGidre:492340

Similar proteinsi

Entry informationi

Entry nameiQ5U392_DANRE
AccessioniPrimary (citable) accession number: Q5U392
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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