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Q5U362

- Q5U362_RAT

UniProt

Q5U362 - Q5U362_RAT

Protein

Annexin

Gene

Anxa4

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium-dependent phospholipid binding Source: UniProtKB-KW
    2. calcium ion binding Source: InterPro

    Keywords - Ligandi

    Calcium, Calcium/phospholipid-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    AnnexinUniRule annotation
    Gene namesi
    Name:Anxa4Imported
    ORF Names:rCG_56369Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 4

    Organism-specific databases

    RGDi621171. Anxa4.

    Expressioni

    Gene expression databases

    GenevestigatoriQ5U362.

    Family & Domainsi

    Domaini

    A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

    Sequence similaritiesi

    Belongs to the annexin family.UniRule annotation
    Contains 4 annexin repeats.UniRule annotation
    Contains annexin repeats.SAAS annotation

    Keywords - Domaini

    AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000115158.
    HOVERGENiHBG061815.
    InParanoidiQ5U362.
    KOiK17093.
    OMAiEQVIVGM.
    OrthoDBiEOG74XS72.
    TreeFamiTF105452.

    Family and domain databases

    Gene3Di1.10.220.10. 4 hits.
    InterProiIPR001464. Annexin.
    IPR018502. Annexin_repeat.
    IPR018252. Annexin_repeat_CS.
    IPR002391. AnnexinIV.
    [Graphical view]
    PANTHERiPTHR10502:SF28. PTHR10502:SF28. 1 hit.
    PfamiPF00191. Annexin. 4 hits.
    [Graphical view]
    PRINTSiPR00196. ANNEXIN.
    SMARTiSM00335. ANX. 4 hits.
    [Graphical view]
    PROSITEiPS00223. ANNEXIN. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5U362-1 [UniParc]FASTAAdd to Basket

    « Hide

    METKGGTVKA ASGFNATEDA QVLRKAMKGL GTDEDAIIGV LACRNTAQRQ    50
    EIRTAYKSTI GRDLLEDLKS ELSSNFEQVI LGMMTPTVLY DVQELRRAMK 100
    GAGTDEGCLI EILASRNPEE IRRINQTYQQ QYGRSLEEDI CSDTSFMFQR 150
    VLVSLTAGGR DEGNYLDDAL VKQDAQDLYE AGEKRWGTDE VKFLSILCSR 200
    NRNHLLHVFD EYKRISQKDI EQSIKSETSG SFEDALLAIV KCMRNKPAYF 250
    AERLYKSMKG LGTDDSTLIR VMVSRAEIDM LDIRANFKRL YGKSLYSFIK 300
    GDTSGDYRKV LLILCGGDD 319
    Length:319
    Mass (Da):35,894
    Last modified:December 7, 2004 - v1
    Checksum:iDE53FBBF2B52464F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06032179 Genomic DNA. No translation available.
    AABR06032180 Genomic DNA. No translation available.
    AABR06032181 Genomic DNA. No translation available.
    AABR06032182 Genomic DNA. No translation available.
    BC085688 mRNA. Translation: AAH85688.1.
    CH473957 Genomic DNA. Translation: EDL91260.1.
    RefSeqiNP_077069.3. NM_024155.3.
    XP_006236903.1. XM_006236841.1.
    XP_006236904.1. XM_006236842.1.
    UniGeneiRn.19270.

    Genome annotation databases

    EnsembliENSRNOT00000024436; ENSRNOP00000024436; ENSRNOG00000018159.
    GeneIDi79124.
    KEGGirno:79124.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06032179 Genomic DNA. No translation available.
    AABR06032180 Genomic DNA. No translation available.
    AABR06032181 Genomic DNA. No translation available.
    AABR06032182 Genomic DNA. No translation available.
    BC085688 mRNA. Translation: AAH85688.1 .
    CH473957 Genomic DNA. Translation: EDL91260.1 .
    RefSeqi NP_077069.3. NM_024155.3.
    XP_006236903.1. XM_006236841.1.
    XP_006236904.1. XM_006236842.1.
    UniGenei Rn.19270.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000024436 ; ENSRNOP00000024436 ; ENSRNOG00000018159 .
    GeneIDi 79124.
    KEGGi rno:79124.

    Organism-specific databases

    CTDi 307.
    RGDi 621171. Anxa4.

    Phylogenomic databases

    GeneTreei ENSGT00740000115158.
    HOVERGENi HBG061815.
    InParanoidi Q5U362.
    KOi K17093.
    OMAi EQVIVGM.
    OrthoDBi EOG74XS72.
    TreeFami TF105452.

    Miscellaneous databases

    NextBioi 614554.

    Gene expression databases

    Genevestigatori Q5U362.

    Family and domain databases

    Gene3Di 1.10.220.10. 4 hits.
    InterProi IPR001464. Annexin.
    IPR018502. Annexin_repeat.
    IPR018252. Annexin_repeat_CS.
    IPR002391. AnnexinIV.
    [Graphical view ]
    PANTHERi PTHR10502:SF28. PTHR10502:SF28. 1 hit.
    Pfami PF00191. Annexin. 4 hits.
    [Graphical view ]
    PRINTSi PR00196. ANNEXIN.
    SMARTi SM00335. ANX. 4 hits.
    [Graphical view ]
    PROSITEi PS00223. ANNEXIN. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: HeartImported.
    2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    5. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiQ5U362_RAT
    AccessioniPrimary (citable) accession number: Q5U362
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 7, 2004
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3