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Protein
Submitted name:

NF-kappa-B inhibitor beta

Gene

Nfkbib

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-1169091. Activation of NF-kappaB in B cells.
R-RNO-1810476. RIP-mediated NFkB activation via ZBP1.
R-RNO-445989. TAK1 activates NFkB by phosphorylation and activation of IKKs complex.
R-RNO-933542. TRAF6 mediated NF-kB activation.

Names & Taxonomyi

Protein namesi
Submitted name:
NF-kappa-B inhibitor betaImported
Submitted name:
Nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, betaImported
Submitted name:
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, betaImported
Gene namesi
Name:NfkbibImported
ORF Names:rCG_54343Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi621887. Nfkbib.

Expressioni

Gene expression databases

BgeeiENSRNOG00000020063.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027212.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 298ANK_REP_REGIONInterPro annotationAdd BLAST242

Sequence similaritiesi

Contains 4 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotation

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00550000074527.
HOVERGENiHBG019039.
KOiK02581.
OMAiDEWCDSG.
OrthoDBiEOG091G092R.
TreeFamiTF320166.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5U342-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVACLGKT ADADEWCDSG LGSLGPDAAA PGGPGLVAEL SPELSWAPLV
60 70 80 90 100
FGYVTEDGDT ALHLAVIHQH EPFLDFLLGF SAGTEYLDLQ NDLGQTALHL
110 120 130 140 150
AAILGEASTV EKLYAAGAGV LVTERGGHTA LHLACRVRAH TCAYVLLQPR
160 170 180 190 200
PSHPRDASDT YLTQSQDHTP DTSHAPVATD PQPNPGNEEE LRDEDWRLQL
210 220 230 240 250
EAENYDGHTP LHVAVIHKDA EMVQLLRDAG ADLNKPEPTC GRTPLHLAVE
260 270 280 290 300
GQAAGVLALL LKAGADPTAR MYGGRTPLGS ALLRPNPVLA RLLRAHGAPE
310 320 330 340 350
PEDEDDKLSP CSNSSSDSDS DNRDEGDEYD DIVVHSRRSQ NQPPPSPAAK

PLPDDPNPA
Length:359
Mass (Da):38,082
Last modified:December 7, 2004 - v1
Checksum:i5660228F5C72B1A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07002849 Genomic DNA. No translation available.
BC085729 mRNA. Translation: AAH85729.1.
CH473979 Genomic DNA. Translation: EDM07877.1.
RefSeqiNP_110494.2. NM_030867.2.
UniGeneiRn.8395.

Genome annotation databases

EnsembliENSRNOT00000027212; ENSRNOP00000027212; ENSRNOG00000020063.
GeneIDi81525.
KEGGirno:81525.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07002849 Genomic DNA. No translation available.
BC085729 mRNA. Translation: AAH85729.1.
CH473979 Genomic DNA. Translation: EDM07877.1.
RefSeqiNP_110494.2. NM_030867.2.
UniGeneiRn.8395.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027212.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000027212; ENSRNOP00000027212; ENSRNOG00000020063.
GeneIDi81525.
KEGGirno:81525.

Organism-specific databases

CTDi4793.
RGDi621887. Nfkbib.

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00550000074527.
HOVERGENiHBG019039.
KOiK02581.
OMAiDEWCDSG.
OrthoDBiEOG091G092R.
TreeFamiTF320166.

Enzyme and pathway databases

ReactomeiR-RNO-1169091. Activation of NF-kappaB in B cells.
R-RNO-1810476. RIP-mediated NFkB activation via ZBP1.
R-RNO-445989. TAK1 activates NFkB by phosphorylation and activation of IKKs complex.
R-RNO-933542. TRAF6 mediated NF-kB activation.

Gene expression databases

BgeeiENSRNOG00000020063.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5U342_RAT
AccessioniPrimary (citable) accession number: Q5U342
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: November 30, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.