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Protein

Zinc finger protein 367

Gene

Znf367

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Transcriptional activator. May be involved in transcriptional activation of erythroid genes (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri157 – 179C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri185 – 209C2H2-type 2PROSITE-ProRule annotationAdd BLAST25

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 367
Gene namesi
Name:Znf367
Synonyms:Zfp367
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 17

Organism-specific databases

RGDi1307136. Zfp367.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002852991 – 340Zinc finger protein 367Add BLAST340

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei300PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5U2Z0.

Expressioni

Gene expression databases

BgeeiENSRNOG00000027234.
GenevisibleiQ5U2Z0. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000030325.

Structurei

3D structure databases

ProteinModelPortaliQ5U2Z0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili299 – 332Sequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi6 – 56Pro-richAdd BLAST51

Sequence similaritiesi

Contains 2 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri157 – 179C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri185 – 209C2H2-type 2PROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00670000098074.
HOGENOMiHOG000049286.
HOVERGENiHBG061619.
InParanoidiQ5U2Z0.
OMAiKYWQTRE.
OrthoDBiEOG091G0H1R.
PhylomeDBiQ5U2Z0.
TreeFamiTF321334.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF13912. zf-C2H2_6. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 2 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5U2Z0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRGAPAPMA EPPPVIFCHD SPKRVLVSVI RTTPATPPCS SVGEPEPPPP
60 70 80 90 100
LVPTSPGFSD FMVYPWRWGE NAHNVTLSPG AAGGVVSAGL PAATELPTLR
110 120 130 140 150
GAPPSSASVA AVSGGEDEEE ASSPDSGHLK DGIRRGRPRA DTVRDLINEG
160 170 180 190 200
EHSSSRIRCN ICNRVFPREK SLQAHKRTHT GERPYLCDYP DCGKAFVQSG
210 220 230 240 250
QLKTHQRLHT GEKPFVCSEN GCLSRFTHAN RHCPKHPYAR LKREEPTDTL
260 270 280 290 300
SKHQSTDNKA AAEWLAKYWE MREQRTPTLK GKLVQKADQE QQDPLEYLQS
310 320 330 340
DEEDDEKSGA QRRLQEQRER LHGALALIEL ANLTGAPLRQ
Length:340
Mass (Da):37,472
Last modified:December 7, 2004 - v1
Checksum:i2EE7433FC103A31A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC085804 mRNA. Translation: AAH85804.1.
RefSeqiNP_001012051.1. NM_001012051.1.
UniGeneiRn.35247.

Genome annotation databases

EnsembliENSRNOT00000036287; ENSRNOP00000030325; ENSRNOG00000027234.
GeneIDi306695.
KEGGirno:306695.
UCSCiRGD:1307136. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC085804 mRNA. Translation: AAH85804.1.
RefSeqiNP_001012051.1. NM_001012051.1.
UniGeneiRn.35247.

3D structure databases

ProteinModelPortaliQ5U2Z0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000030325.

Proteomic databases

PaxDbiQ5U2Z0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000036287; ENSRNOP00000030325; ENSRNOG00000027234.
GeneIDi306695.
KEGGirno:306695.
UCSCiRGD:1307136. rat.

Organism-specific databases

CTDi238673.
RGDi1307136. Zfp367.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00670000098074.
HOGENOMiHOG000049286.
HOVERGENiHBG061619.
InParanoidiQ5U2Z0.
OMAiKYWQTRE.
OrthoDBiEOG091G0H1R.
PhylomeDBiQ5U2Z0.
TreeFamiTF321334.

Miscellaneous databases

PROiQ5U2Z0.

Gene expression databases

BgeeiENSRNOG00000027234.
GenevisibleiQ5U2Z0. RN.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF13912. zf-C2H2_6. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 2 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZN367_RAT
AccessioniPrimary (citable) accession number: Q5U2Z0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: December 7, 2004
Last modified: September 7, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.