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Protein
Submitted name:

Bcl2-associated athanogene 3

Gene

Bag3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • adenyl-nucleotide exchange factor activity Source: Ensembl
  • protein complex binding Source: RGD

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-3371453. Regulation of HSF1-mediated heat shock response.

Names & Taxonomyi

Protein namesi
Submitted name:
Bcl2-associated athanogene 3Imported
Submitted name:
Protein Bag3Imported
Submitted name:
RCG40209, isoform CRA_bImported
Gene namesi
Name:Bag3Imported
ORF Names:rCG_40209Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1307794. Bag3.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: Ensembl
  • neuron projection Source: RGD
  • plasma membrane Source: Ensembl
  • Z disc Source: Ensembl
Complete GO annotation...

Interactioni

GO - Molecular functioni

  • protein complex binding Source: RGD

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027616.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini22 – 5635WWInterPro annotationAdd
BLAST
Domaini423 – 50078BAGInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0940. Eukaryota.
KOG4361. Eukaryota.
COG5021. LUCA.
GeneTreeiENSGT00530000063256.
HOVERGENiHBG003419.
KOiK09557.
OMAiVYPQLRP.
OrthoDBiEOG75B85S.
TreeFamiTF102013.

Family and domain databases

Gene3Di1.20.58.120. 1 hit.
InterProiIPR003103. BAG_domain.
IPR001202. WW_dom.
[Graphical view]
PfamiPF02179. BAG. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTiSM00264. BAG. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
SSF63491. SSF63491. 1 hit.
PROSITEiPS51035. BAG. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5U2U8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAATQSPVM QMASGNGASD RDPLPPGWEI KIDPQTGWPF FVDHNSRTTT
60 70 80 90 100
WNDPRVPPEG PKETASSANG PSRDGSRLLP AREGHPIYPQ LRPGYIPIPV
110 120 130 140 150
HHEGSENRQP HLFHAYSQPG VQRFRTEAAA AAPQRSQSPL RGGVTETTQT
160 170 180 190 200
DKQCGQVPAA ATAQPPTAHG PERSQSPAAS DCSSSSSSAS LPSSGRSSLG
210 220 230 240 250
SHQLPRGYIP IPVIHEQNIT RPAAQPSFHQ AQKTHYPAQQ GEYQPQQPVY
260 270 280 290 300
HKIQGDDWEP RPLRATSPFR SPVRGASSRE GSPARSGTPV HCPSPIRVHT
310 320 330 340 350
VVDRPQPMTH REPPPVTQPE NKPESKPGLA GPDLPPGHIP IQVIRREADS
360 370 380 390 400
KPVSQKPPPP AEKVEVKVSS APIPCPSPGP APSAVPSSPK NVAAEPKAAP
410 420 430 440 450
SPAPAEAASL KSGDAEAPHK HPGVLKVEAI LEKVQGLEQA VDNFEGKKTD
460 470 480 490 500
KKYLMIEEYL TKELLALDSV DPEGRADVRQ ARRDGVRKVQ TILEKLEQKA
510 520 530 540 550
IDVPGQVQVY ELQPSNLEPE QPLQEIMGAV AADKDKKGPE NEDPQTESQQ
560 570
LEAKAATPPN PSSTADSAGN PVAP
Length:574
Mass (Da):61,491
Last modified:December 7, 2004 - v1
Checksum:i49C3858E5BA0F1C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07005786 Genomic DNA. No translation available.
BC085857 mRNA. Translation: AAH85857.1.
CH473956 Genomic DNA. Translation: EDM17171.1.
RefSeqiNP_001011936.1. NM_001011936.1.
UniGeneiRn.46304.

Genome annotation databases

EnsembliENSRNOT00000027616; ENSRNOP00000027616; ENSRNOG00000020298.
GeneIDi293524.
KEGGirno:293524.
UCSCiRGD:1307794. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07005786 Genomic DNA. No translation available.
BC085857 mRNA. Translation: AAH85857.1.
CH473956 Genomic DNA. Translation: EDM17171.1.
RefSeqiNP_001011936.1. NM_001011936.1.
UniGeneiRn.46304.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027616.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000027616; ENSRNOP00000027616; ENSRNOG00000020298.
GeneIDi293524.
KEGGirno:293524.
UCSCiRGD:1307794. rat.

Organism-specific databases

CTDi9531.
RGDi1307794. Bag3.

Phylogenomic databases

eggNOGiKOG0940. Eukaryota.
KOG4361. Eukaryota.
COG5021. LUCA.
GeneTreeiENSGT00530000063256.
HOVERGENiHBG003419.
KOiK09557.
OMAiVYPQLRP.
OrthoDBiEOG75B85S.
TreeFamiTF102013.

Enzyme and pathway databases

ReactomeiR-RNO-3371453. Regulation of HSF1-mediated heat shock response.

Family and domain databases

Gene3Di1.20.58.120. 1 hit.
InterProiIPR003103. BAG_domain.
IPR001202. WW_dom.
[Graphical view]
PfamiPF02179. BAG. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTiSM00264. BAG. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
SSF63491. SSF63491. 1 hit.
PROSITEiPS51035. BAG. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: HeartImported.
  2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  5. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiQ5U2U8_RAT
AccessioniPrimary (citable) accession number: Q5U2U8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: June 8, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.