Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Lymphotoxin B receptor

Gene

Ltbr

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Enzyme and pathway databases

ReactomeiR-RNO-5668541. TNFR2 non-canonical NF-kB pathway.
R-RNO-5676594. TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
Lymphotoxin B receptorImported
Submitted name:
Lymphotoxin beta receptor (TNFR superfamily, member 3)Imported
Submitted name:
Protein LtbrImported
Gene namesi
Name:LtbrImported
ORF Names:rCG_29964Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1309448. Ltbr.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei222 – 245HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500878163228 – 416Sequence analysisAdd BLAST389

Expressioni

Gene expression databases

BgeeiENSRNOG00000019264.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026184.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 80TNFR-CysInterPro annotationAdd BLAST39
Domaini82 – 124TNFR-CysInterPro annotationAdd BLAST43
Domaini171 – 212TNFR-CysInterPro annotationAdd BLAST42

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IKNN. Eukaryota.
ENOG410YQJW. LUCA.
GeneTreeiENSGT00760000119204.
HOGENOMiHOG000294180.
HOVERGENiHBG023187.
KOiK03159.
OMAiQLCRPCD.
OrthoDBiEOG091G03XW.
TreeFamiTF331157.

Family and domain databases

InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
IPR017349. TNFR_3_LTBR.
[Graphical view]
PfamiPF00020. TNFR_c6. 3 hits.
[Graphical view]
PIRSFiPIRSF037999. TNFR_3_LTBR. 1 hit.
PRINTSiPR01920. TNFACTORR3.
SMARTiSM00208. TNFR. 3 hits.
[Graphical view]
PROSITEiPS00652. TNFR_NGFR_1. 2 hits.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5U2S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLPGASSPC GLVWGPLLLG FCGLLVASQP QLVPPYRIEN QTCWDPDKEY
60 70 80 90 100
YEPLHQVCCS RCPPGKFVHA VCSPSQDTVC KTCLHNSYNE HWNHLFSCQL
110 120 130 140 150
CRPCDSVLGF EEIAPCTSDR KPECRCKPGM SCVYLDNECV HCEEERLVLC
160 170 180 190 200
RPGTEAEVTD EIMDTEVNCV PCKPGHFQNT SSPRARCQPH TRCESQGLVE
210 220 230 240 250
AASGTSYSDT ICKNPPEAAG TMLLLAILLS LVFFLLFTTV LACAWMRHPS
260 270 280 290 300
LCRKLGTLLK RHPEGEESPP CQPPRANPHF RDLAEPLLPM SGDLSPAPAG
310 320 330 340 350
PPTAPSLEEV VLQQQSPLIQ ARELEAEPGE HGQVAHGANG IHVTGGSVTV
360 370 380 390 400
TGNIYIYNGP VLGGTRGPGD PPAPPEPPYP TPEEGAPGPS ELSTPYQEDG
410
KAWHLAETET LGCQDL
Length:416
Mass (Da):45,133
Last modified:December 7, 2004 - v1
Checksum:i77AC87D7E72FAE5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07062033 Genomic DNA. No translation available.
BC085880 mRNA. Translation: AAH85880.1.
CH473964 Genomic DNA. Translation: EDM01849.1.
RefSeqiNP_001008316.1. NM_001008315.1.
UniGeneiRn.19329.

Genome annotation databases

EnsembliENSRNOT00000026184; ENSRNOP00000026184; ENSRNOG00000019264.
GeneIDi297604.
KEGGirno:297604.
UCSCiRGD:1309448. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07062033 Genomic DNA. No translation available.
BC085880 mRNA. Translation: AAH85880.1.
CH473964 Genomic DNA. Translation: EDM01849.1.
RefSeqiNP_001008316.1. NM_001008315.1.
UniGeneiRn.19329.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026184.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000026184; ENSRNOP00000026184; ENSRNOG00000019264.
GeneIDi297604.
KEGGirno:297604.
UCSCiRGD:1309448. rat.

Organism-specific databases

CTDi4055.
RGDi1309448. Ltbr.

Phylogenomic databases

eggNOGiENOG410IKNN. Eukaryota.
ENOG410YQJW. LUCA.
GeneTreeiENSGT00760000119204.
HOGENOMiHOG000294180.
HOVERGENiHBG023187.
KOiK03159.
OMAiQLCRPCD.
OrthoDBiEOG091G03XW.
TreeFamiTF331157.

Enzyme and pathway databases

ReactomeiR-RNO-5668541. TNFR2 non-canonical NF-kB pathway.
R-RNO-5676594. TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway.

Gene expression databases

BgeeiENSRNOG00000019264.

Family and domain databases

InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
IPR017349. TNFR_3_LTBR.
[Graphical view]
PfamiPF00020. TNFR_c6. 3 hits.
[Graphical view]
PIRSFiPIRSF037999. TNFR_3_LTBR. 1 hit.
PRINTSiPR01920. TNFACTORR3.
SMARTiSM00208. TNFR. 3 hits.
[Graphical view]
PROSITEiPS00652. TNFR_NGFR_1. 2 hits.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5U2S8_RAT
AccessioniPrimary (citable) accession number: Q5U2S8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: November 30, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.