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Q5U1Y5

- Q5U1Y5_RAT

UniProt

Q5U1Y5 - Q5U1Y5_RAT

Protein
Submitted name:

Heterogenous nuclear ribonucleoprotein L

Gene

Fblim1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. nucleotide binding Source: InterPro
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. mRNA processing Source: InterPro

    Keywords - Molecular functioni

    RibonucleoproteinImported

    Keywords - Ligandi

    Viral nucleoproteinImported

    Enzyme and pathway databases

    ReactomeiREACT_208719. mRNA Splicing - Major Pathway.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Heterogenous nuclear ribonucleoprotein LImported
    Submitted name:
    Hnrpl proteinImported
    Submitted name:
    Protein HnrnplImported
    Gene namesi
    Name:Fblim1Imported
    Synonyms:hnrnp-LImported, HnrnplImported, HnrplImported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 1

    Organism-specific databases

    RGDi1359551. Fblim1.
    71059. Hnrnpl.

    Subcellular locationi

    GO - Cellular componenti

    1. pronucleus Source: Ensembl
    2. ribonucleoprotein complex Source: UniProtKB-KW
    3. viral nucleocapsid Source: UniProtKB-KW

    Keywords - Cellular componenti

    Virion

    Expressioni

    Gene expression databases

    GenevestigatoriQ5U1Y5.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00550000074508.
    HOGENOMiHOG000293298.
    HOVERGENiHBG058843.
    InParanoidiQ5U1Y5.
    TreeFamiTF354318.

    Family and domain databases

    Gene3Di3.30.70.330. 2 hits.
    InterProiIPR006536. HnRNP-L_PTB.
    IPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view]
    SMARTiSM00360. RRM. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01649. hnRNP-L_PTB. 1 hit.
    PROSITEiPS50102. RRM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5U1Y5-1 [UniParc]FASTAAdd to Basket

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    MGPPVGGHRR GPSRYGPQYG HPPPPPPPPD YGPHADSPVL MVYGLDQSKM    50
    NCDRVFNVFC LYGNVEKVKF MKSKPGAAMV EMADGYAVDR AITHLNNNFM 100
    FGQKMNVCVS KQPAIMPGQS YGLEDGSCSY KDFSESRNNR FSTPEQAAKN 150
    RIQHPSNVLH FFNAPLEVTE ENFFEICDEL GVKRPTSVKV FSGKSERSSS 200
    GLLEWDSKSD ALETLGFLNH YQMKNPNGPY PYTLKLCFST AQHAS 245
    Length:245
    Mass (Da):27,251
    Last modified:December 7, 2004 - v1
    Checksum:i4F814C3211650207
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06004215 Genomic DNA. No translation available.
    BC086392 mRNA. Translation: AAH86392.1.
    AB260892 mRNA. Translation: BAG72209.1.
    UniGeneiRn.33873.

    Genome annotation databases

    EnsembliENSRNOT00000057034; ENSRNOP00000053867; ENSRNOG00000020235.
    UCSCiRGD:1359551. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06004215 Genomic DNA. No translation available.
    BC086392 mRNA. Translation: AAH86392.1 .
    AB260892 mRNA. Translation: BAG72209.1 .
    UniGenei Rn.33873.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000057034 ; ENSRNOP00000053867 ; ENSRNOG00000020235 .
    UCSCi RGD:1359551. rat.

    Organism-specific databases

    RGDi 1359551. Fblim1.
    71059. Hnrnpl.

    Phylogenomic databases

    GeneTreei ENSGT00550000074508.
    HOGENOMi HOG000293298.
    HOVERGENi HBG058843.
    InParanoidi Q5U1Y5.
    TreeFami TF354318.

    Enzyme and pathway databases

    Reactomei REACT_208719. mRNA Splicing - Major Pathway.

    Miscellaneous databases

    NextBioi 614884.

    Gene expression databases

    Genevestigatori Q5U1Y5.

    Family and domain databases

    Gene3Di 3.30.70.330. 2 hits.
    InterProi IPR006536. HnRNP-L_PTB.
    IPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view ]
    SMARTi SM00360. RRM. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01649. hnRNP-L_PTB. 1 hit.
    PROSITEi PS50102. RRM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: OvaryImported.
    2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    3. "Natural antisense transcript stabilizes inducible nitric oxide synthase messenger RNA in rat hepatocytes."
      Matsui K., Nishizawa M., Ozaki T., Kimura T., Hashimoto I., Yamada M., Kaibori M., Kamiyama Y., Ito S., Okumura T.
      Hepatology 47:686-697(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: WistarImported.
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiQ5U1Y5_RAT
    AccessioniPrimary (citable) accession number: Q5U1Y5
    Secondary accession number(s): F1LPP9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 7, 2004
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3