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Protein
Submitted name:

Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP-binding protein Rac2)

Gene

Rac2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-114604. GPVI-mediated activation cascade.
R-RNO-194840. Rho GTPase cycle.
R-RNO-416482. G alpha (12/13) signalling events.
R-RNO-416572. Sema4D induced cell migration and growth-cone collapse.
R-RNO-5668599. RHO GTPases Activate NADPH Oxidases.

Names & Taxonomyi

Protein namesi
Submitted name:
Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP-binding protein Rac2)Imported
Gene namesi
Name:Rac2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1307568. Rac2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000007350.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009994.

Structurei

3D structure databases

SMRiQ5U1Y2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rho family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0393. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00760000118978.
HOGENOMiHOG000233974.
HOVERGENiHBG009351.
KOiK07860.
OMAiRRGCSIF.
OrthoDBiEOG091G0KCM.
TreeFamiTF101109.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003578. Small_GTPase_Rho.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51420. RHO. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5U1Y2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP
60 70 80 90 100
VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE
110 120 130 140 150
VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKDID
160 170 180 190
SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRPCS LL
Length:192
Mass (Da):21,441
Last modified:December 7, 2004 - v1
Checksum:i2A1F1266AB9D7705
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058502 Genomic DNA. No translation available.
BC086399 mRNA. Translation: AAH86399.1.
RefSeqiNP_001008385.1. NM_001008384.1.
XP_006242090.1. XM_006242028.2.
UniGeneiRn.2863.

Genome annotation databases

EnsembliENSRNOT00000009994; ENSRNOP00000009994; ENSRNOG00000007350.
GeneIDi366957.
KEGGirno:366957.
UCSCiRGD:1307568. rat.

Similar proteinsi

Entry informationi

Entry nameiQ5U1Y2_RAT
AccessioniPrimary (citable) accession number: Q5U1Y2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: September 27, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported