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Protein

U11/U12 small nuclear ribonucleoprotein 35 kDa protein

Gene

Snrnp35

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. nucleotide binding Source: InterPro
  2. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. mRNA processing Source: UniProtKB-KW
  2. RNA splicing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

mRNA processing, mRNA splicing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
U11/U12 small nuclear ribonucleoprotein 35 kDa protein
Short name:
U11/U12 snRNP 35 kDa protein
Alternative name(s):
U1 snRNP-binding protein homolog
Gene namesi
Name:Snrnp35
Synonyms:U1snrnpbp
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1310724. Snrnp35.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. spliceosomal complex Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 244244U11/U12 small nuclear ribonucleoprotein 35 kDa proteinPRO_0000307909Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriQ5U1W5.

Interactioni

Subunit structurei

Component of the U11/U12 snRNPs that are part of the U12-type spliceosome.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001402.

Structurei

3D structure databases

ProteinModelPortaliQ5U1W5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini51 – 12979RRMPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi154 – 24289Arg-richAdd
BLAST

Sequence similaritiesi

Contains 1 RRM (RNA recognition motif) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0724.
HOGENOMiHOG000006374.
HOVERGENiHBG104583.
InParanoidiQ5U1W5.
KOiK13155.
PhylomeDBiQ5U1W5.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
[Graphical view]
PROSITEiPS50102. RRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5U1W5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDWMPIAKE YDPLKAGSID GTDEDPHDRA VWRAMLARYV PNKGVTGDPL
60 70 80 90 100
LTLFVARLNS QTKEEKLKEV FSRYGDIRRL RLVRDLVTGF SKGYAFIEYK
110 120 130 140 150
EERALLKAYR DADGLVIDQH EIFVDYELER TLRGWIPRRL GGGLGGKKES
160 170 180 190 200
GQLRFGGRDR PFRKPINLPV VKNEPHREGK RERRERSRSR DRHWDPRPRE
210 220 230 240
RDHDRGREKH WQDRARVWPE NDWEREREFR DERAKTRDKR DRSK
Length:244
Mass (Da):29,204
Last modified:December 6, 2004 - v1
Checksum:i07B008D0AF05575B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086435 mRNA. Translation: AAH86435.1.
RefSeqiNP_001014149.1. NM_001014127.1.
UniGeneiRn.79076.

Genome annotation databases

GeneIDi360803.
KEGGirno:360803.
UCSCiRGD:1310724. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086435 mRNA. Translation: AAH86435.1.
RefSeqiNP_001014149.1. NM_001014127.1.
UniGeneiRn.79076.

3D structure databases

ProteinModelPortaliQ5U1W5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001402.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi360803.
KEGGirno:360803.
UCSCiRGD:1310724. rat.

Organism-specific databases

CTDi11066.
RGDi1310724. Snrnp35.

Phylogenomic databases

eggNOGiCOG0724.
HOGENOMiHOG000006374.
HOVERGENiHBG104583.
InParanoidiQ5U1W5.
KOiK13155.
PhylomeDBiQ5U1W5.

Miscellaneous databases

NextBioi674154.
PROiQ5U1W5.

Gene expression databases

GenevestigatoriQ5U1W5.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
[Graphical view]
PROSITEiPS50102. RRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Ovary.

Entry informationi

Entry nameiU1SBP_RAT
AccessioniPrimary (citable) accession number: Q5U1W5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 22, 2007
Last sequence update: December 6, 2004
Last modified: January 6, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.