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Q5U1W5

- U1SBP_RAT

UniProt

Q5U1W5 - U1SBP_RAT

Protein

U11/U12 small nuclear ribonucleoprotein 35 kDa protein

Gene

Snrnp35

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. nucleotide binding Source: InterPro
    2. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. mRNA processing Source: UniProtKB-KW
    2. RNA splicing Source: UniProtKB-KW

    Keywords - Biological processi

    mRNA processing, mRNA splicing

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    U11/U12 small nuclear ribonucleoprotein 35 kDa protein
    Short name:
    U11/U12 snRNP 35 kDa protein
    Alternative name(s):
    U1 snRNP-binding protein homolog
    Gene namesi
    Name:Snrnp35
    Synonyms:U1snrnpbp
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Unplaced

    Organism-specific databases

    RGDi1310724. Snrnp35.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. spliceosomal complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    Nucleus, Spliceosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 244244U11/U12 small nuclear ribonucleoprotein 35 kDa proteinPRO_0000307909Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriQ5U1W5.

    Interactioni

    Subunit structurei

    Component of the U11/U12 snRNPs that are part of the U12-type spliceosome.By similarity

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000001402.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5U1W5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini51 – 12979RRMPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi154 – 24289Arg-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 RRM (RNA recognition motif) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0724.
    HOGENOMiHOG000006374.
    HOVERGENiHBG104583.
    InParanoidiQ5U1W5.
    KOiK13155.
    PhylomeDBiQ5U1W5.

    Family and domain databases

    Gene3Di3.30.70.330. 1 hit.
    InterProiIPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view]
    PfamiPF00076. RRM_1. 1 hit.
    [Graphical view]
    SMARTiSM00360. RRM. 1 hit.
    [Graphical view]
    PROSITEiPS50102. RRM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5U1W5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDWMPIAKE YDPLKAGSID GTDEDPHDRA VWRAMLARYV PNKGVTGDPL    50
    LTLFVARLNS QTKEEKLKEV FSRYGDIRRL RLVRDLVTGF SKGYAFIEYK 100
    EERALLKAYR DADGLVIDQH EIFVDYELER TLRGWIPRRL GGGLGGKKES 150
    GQLRFGGRDR PFRKPINLPV VKNEPHREGK RERRERSRSR DRHWDPRPRE 200
    RDHDRGREKH WQDRARVWPE NDWEREREFR DERAKTRDKR DRSK 244
    Length:244
    Mass (Da):29,204
    Last modified:December 7, 2004 - v1
    Checksum:i07B008D0AF05575B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC086435 mRNA. Translation: AAH86435.1.
    RefSeqiNP_001014149.1. NM_001014127.1.
    UniGeneiRn.79076.

    Genome annotation databases

    GeneIDi360803.
    KEGGirno:360803.
    UCSCiRGD:1310724. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC086435 mRNA. Translation: AAH86435.1 .
    RefSeqi NP_001014149.1. NM_001014127.1.
    UniGenei Rn.79076.

    3D structure databases

    ProteinModelPortali Q5U1W5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000001402.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 360803.
    KEGGi rno:360803.
    UCSCi RGD:1310724. rat.

    Organism-specific databases

    CTDi 11066.
    RGDi 1310724. Snrnp35.

    Phylogenomic databases

    eggNOGi COG0724.
    HOGENOMi HOG000006374.
    HOVERGENi HBG104583.
    InParanoidi Q5U1W5.
    KOi K13155.
    PhylomeDBi Q5U1W5.

    Miscellaneous databases

    NextBioi 674154.
    PROi Q5U1W5.

    Gene expression databases

    Genevestigatori Q5U1W5.

    Family and domain databases

    Gene3Di 3.30.70.330. 1 hit.
    InterProi IPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view ]
    Pfami PF00076. RRM_1. 1 hit.
    [Graphical view ]
    SMARTi SM00360. RRM. 1 hit.
    [Graphical view ]
    PROSITEi PS50102. RRM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Ovary.

    Entry informationi

    Entry nameiU1SBP_RAT
    AccessioniPrimary (citable) accession number: Q5U1W5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3