Q5U1W5 (U1SBP_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
U11/U12 small nuclear ribonucleoprotein 35 kDa protein
Short name=U11/U12 snRNP 35 kDa protein

Alternative name(s):
U1 snRNP-binding protein homolog

Gene names

Name:	Snrnp35
Synonyms:	U1snrnpbp

Organism

Rattus norvegicus (Rat) [Reference proteome]

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	244 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subunit structure	Component of the U11/U12 snRNPs that are part of the U12-type spliceosome By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Contains 1 RRM (RNA recognition motif) domain.

Ontologies

Keywords
Biological process	mRNA processing mRNA splicing
Cellular component	Nucleus Spliceosome
Ligand	RNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	RNA splicing Inferred from electronic annotation. Source: UniProtKB-KW mRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	spliceosomal complex Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 244	244	U11/U12 small nuclear ribonucleoprotein 35 kDa protein		PRO_0000307909
Regions
	Domain	51 – 129	79	RRM
	Compositional bias	154 – 242	89	Arg-rich

Sequences

	Sequence		Length	Mass (Da)
	Q5U1W5 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: 07B008D0AF05575B	FASTA	244	29,204
	10 20 30 40 50 60 MSDWMPIAKE YDPLKAGSID GTDEDPHDRA VWRAMLARYV PNKGVTGDPL LTLFVARLNS 70 80 90 100 110 120 QTKEEKLKEV FSRYGDIRRL RLVRDLVTGF SKGYAFIEYK EERALLKAYR DADGLVIDQH 130 140 150 160 170 180 EIFVDYELER TLRGWIPRRL GGGLGGKKES GQLRFGGRDR PFRKPINLPV VKNEPHREGK 190 200 210 220 230 240 RERRERSRSR DRHWDPRPRE RDHDRGREKH WQDRARVWPE NDWEREREFR DERAKTRDKR DRSK

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Ovary.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC086435 mRNA. Translation: AAH86435.1.
IPI	IPI00189830.
RefSeq	NP_001014149.1. NM_001014127.1.
UniGene	Rn.79076.
3D structure databases
ProteinModelPortal	Q5U1W5.
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000001402.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	360803.
KEGG	rno:360803.
UCSC	RGD:1310724. rat.
Organism-specific databases
CTD	11066.
RGD	1310724. Snrnp35.
Phylogenomic databases
eggNOG	COG0724.
HOGENOM	HOG000006374.
HOVERGEN	HBG104583.
InParanoid	Q5U1W5.
KO	K13155.
OrthoDB	EOG4MSD0C.
Gene expression databases
Genevestigator	Q5U1W5.
Family and domain databases
Gene3D	3.30.70.330. 1 hit.
InterPro	IPR012677. Nucleotide-bd_a/b_plait. IPR000504. RRM_dom. [Graphical view]
Pfam	PF00076. RRM_1. 1 hit. [Graphical view]
SMART	SM00360. RRM. 1 hit. [Graphical view]
PROSITE	PS50102. RRM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	674154.

Entry information

Entry name

U1SBP_RAT

Accession

Primary (citable) accession number: Q5U1W5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
Last sequence update:	December 7, 2004
Last modified:	May 29, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program