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Protein

Tetraspanin-31

Gene

Tspan31

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Tetraspanin-31
Short name:
Tspan-31
Alternative name(s):
Sarcoma-amplified sequence homolog
Gene namesi
Name:Tspan31
Synonyms:Sas
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1309876. Tspan31.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1212CytoplasmicSequence analysisAdd
BLAST
Transmembranei13 – 3321HelicalSequence analysisAdd
BLAST
Topological domaini34 – 4411ExtracellularSequence analysisAdd
BLAST
Transmembranei45 – 6521HelicalSequence analysisAdd
BLAST
Topological domaini66 – 727CytoplasmicSequence analysis
Transmembranei73 – 9321HelicalSequence analysisAdd
BLAST
Topological domaini94 – 17380ExtracellularSequence analysisAdd
BLAST
Transmembranei174 – 19421HelicalSequence analysisAdd
BLAST
Topological domaini195 – 21016CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 210210Tetraspanin-31PRO_0000219274Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi109 – 1091N-linked (GlcNAc...)Sequence analysis
Glycosylationi117 – 1171N-linked (GlcNAc...)Sequence analysis
Glycosylationi134 – 1341N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ5U1V9.
PRIDEiQ5U1V9.

Expressioni

Gene expression databases

GenevisibleiQ5U1V9. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000036976.

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3882. Eukaryota.
ENOG4111IRY. LUCA.
GeneTreeiENSGT00500000044851.
HOGENOMiHOG000005650.
HOVERGENiHBG009195.
InParanoidiQ5U1V9.
KOiK17356.
OMAiYQQDYAF.
OrthoDBiEOG7D2FFF.
PhylomeDBiQ5U1V9.
TreeFamiTF323367.

Family and domain databases

InterProiIPR000301. Tetraspanin.
IPR018499. Tetraspanin/Peripherin.
[Graphical view]
PfamiPF00335. Tetraspannin. 1 hit.
[Graphical view]
PIRSFiPIRSF002419. Tetraspanin. 1 hit.
PRINTSiPR00259. TMFOUR.

Sequencei

Sequence statusi: Complete.

Q5U1V9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACGGFACSK NALCALNVVY MLVGLLLIGV AAWGKGLGVV SSIHIIGGVI
60 70 80 90 100
AVGVFLLLIA VAGLVGAVNH HQVLLFFYMI ILGLVFIFQF GISCSCLAIN
110 120 130 140 150
RNTQADVINA SWWVLSNSTR HELERSFDCC GLFNLTTVHL HDDASCSALC
160 170 180 190 200
KTRSSPCQMC GETFLKHSDK ALKILGGVGL FFSFTEILGV WLAMRFRNQK
210
DPRANPSAFL
Length:210
Mass (Da):22,660
Last modified:December 7, 2004 - v1
Checksum:iEF4ED06C93A3A475
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086452 mRNA. Translation: AAH86452.1.
RefSeqiNP_001008379.1. NM_001008378.1.
UniGeneiRn.129220.

Genome annotation databases

EnsembliENSRNOT00000031272; ENSRNOP00000036976; ENSRNOG00000025592.
GeneIDi362890.
KEGGirno:362890.
UCSCiRGD:1309876. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086452 mRNA. Translation: AAH86452.1.
RefSeqiNP_001008379.1. NM_001008378.1.
UniGeneiRn.129220.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000036976.

Proteomic databases

PaxDbiQ5U1V9.
PRIDEiQ5U1V9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000031272; ENSRNOP00000036976; ENSRNOG00000025592.
GeneIDi362890.
KEGGirno:362890.
UCSCiRGD:1309876. rat.

Organism-specific databases

CTDi6302.
RGDi1309876. Tspan31.

Phylogenomic databases

eggNOGiKOG3882. Eukaryota.
ENOG4111IRY. LUCA.
GeneTreeiENSGT00500000044851.
HOGENOMiHOG000005650.
HOVERGENiHBG009195.
InParanoidiQ5U1V9.
KOiK17356.
OMAiYQQDYAF.
OrthoDBiEOG7D2FFF.
PhylomeDBiQ5U1V9.
TreeFamiTF323367.

Miscellaneous databases

PROiQ5U1V9.

Gene expression databases

GenevisibleiQ5U1V9. RN.

Family and domain databases

InterProiIPR000301. Tetraspanin.
IPR018499. Tetraspanin/Peripherin.
[Graphical view]
PfamiPF00335. Tetraspannin. 1 hit.
[Graphical view]
PIRSFiPIRSF002419. Tetraspanin. 1 hit.
PRINTSiPR00259. TMFOUR.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Ovary.

Entry informationi

Entry nameiTSN31_RAT
AccessioniPrimary (citable) accession number: Q5U1V9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: December 7, 2004
Last modified: July 6, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.