Q5U127 (Q5U127_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LP11827p EMBL AAV36950.1

Gene names

Name:	Dcp2 FlyBase FBgn0036534
ORF Names:	CG6169 EMBL AAV36950.1 FlyBase FBgn0036534

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	792 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	deadenylation-dependent decapping of nuclear-transcribed mRNA Inferred from direct assay. Source: FlyBase gene silencing by miRNA Inferred from mutant phenotype. Source: FlyBase regulation of cytoplasmic mRNA processing body assembly Inferred from mutant phenotype. Source: FlyBase
Cellular component	cytoplasmic mRNA processing body Inferred from direct assay. Source: FlyBase
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro m7G(5')pppN diphosphatase activity Inferred from direct assay. Source: FlyBase manganese ion binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: UniProtKB
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5U127 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: 68D67F06B314103C	FASTA	792	87,619
	10 20 30 40 50 60 MEIAPLINNA VAVVTASASA AVSASASVGS SSKDDNVNNL ALLASLTLQK VLNINNNNNQ 70 80 90 100 110 120 HSKNNNHSDN SNSKQHEQQK QQQQPQRRNL DIKSEYDVLN QLLKTGAVFT ATPTAPIAIE 130 140 150 160 170 180 RRKQTQQQQR PYAQQAHQQQ QQKQRLNSSI SSTHSSTSTN SSYGSSSSED AAGTSAPTGA 190 200 210 220 230 240 GEVVTSAALT PRASTTKASS NKLPEKSKIP SDILDDLASR FIINVPDMEL NNLIRMCFQI 250 260 270 280 290 300 ELAHWFYLDF FCAPESGEDG ETPKCVQRKL PSVGIKQFAM QLFQHIPFLN KHFGTVDQIL 310 320 330 340 350 360 DEWKNYKLSV PTYGAILVSE DHNHCLLVQS YFARNSWGFP KGKINENEDP AHCATREVYE 370 380 390 400 410 420 ETGFDITDLI DANDYIEAFI NYQYTRLYVV RNIPMDTQFA PRTRNEIKCC DWFRIDALPV 430 440 450 460 470 480 NKNDAISKAK LGKTSNSFFM IMPFVKRLKK WVNDRKAGIE PRRRKFSGQQ SPKAASPTNM 490 500 510 520 530 540 NGNCKKDVTG VRNESQRQRH KSMGDLDGVK LNNLNGKGTV GTGAGSAASA SATAAINSMN 550 560 570 580 590 600 ICNSNGKRNK QNAAAGSNQA TPTTIATPMT SNGAVVGGTV SSKRQLFHSQ SQNDAQQSAS 610 620 630 640 650 660 NEKQIVSSFD LIRKEKQQQL KAAKAQKQQQ QQQQRSRTKS QSDKQYNPQQ PVKILGQQQP 670 680 690 700 710 720 TTGMDLIAML SAAAAAQKTP NNEQQTQEKQ QQQQRPRPAS VSLNLGAGSA TGATTSAPDA 730 740 750 760 770 780 QYMHRLQRMA SGTNLRILKR AQSQQPQQHH QQQLQLEQQQ QQQQQLGIDF TPNLNSWTNF 790 SFTKNFIANV FC

References

[1]	Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., Park S., Wan K., Yu C., Rubin G.M., Celniker S. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAV36950.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BT016065 mRNA. Translation: AAV36950.1.
3D structure databases
ProteinModelPortal	Q5U127.
SMR	Q5U127. Positions 210-459.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q5U127. 2 interactions.
STRING	Q5U127.
Proteomic databases
PRIDE	Q5U127.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0304975; FBpp0293514; FBgn0036534.
Organism-specific databases
FlyBase	FBgn0036534. Dcp2.
Phylogenomic databases
eggNOG	inNOG08367.
InParanoid	Q5U127.
OrthoDB	EOG4G1JZ9.
PhylomeDB	Q5U127.
Gene expression databases
ArrayExpress	Q5U127.
Bgee	Q5U127.
Family and domain databases
InterPro	IPR007722. mRNA_decapping_BoxA. IPR020084. NUDIX_hydrolase_CS. IPR000086. NUDIX_hydrolase_dom. IPR015797. NUDIX_hydrolase_dom-like. [Graphical view]
Gene3D	G3DSA:3.90.79.10. NUDIX_hydrolase. 1 hit.
Pfam	PF05026. DCP2. 1 hit. PF00293. NUDIX. 1 hit. [Graphical view]
SUPFAM	SSF55811. NUDIX_hydrolase. 1 hit.
PROSITE	PS51462. NUDIX. 1 hit. PS00893. NUDIX_BOX. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5U127_DROME

Accession

Primary (citable) accession number: Q5U127

Entry history

Integrated into UniProtKB/TrEMBL:	December 7, 2004
Last sequence update:	December 7, 2004
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)