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Protein
Submitted name:

Ras-GTPase-activating protein SH3-domain-binding protein, isoform CRA_a

Gene

DKFZp686L1159

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ras-GTPase-activating protein SH3-domain-binding protein, isoform CRA_aImported
Submitted name:
cDNA, FLJ92947, Homo sapiens Ras-GTPase-activating protein SH3-domain-bindingprotein (G3BP), mRNAImported
Gene namesi
Name:DKFZp686L1159Imported
Synonyms:G3BPImported
ORF Names:hCG_39146Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000145907.14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162389105

PTM / Processingi

Proteomic databases

MaxQBiQ5U0Q1
PRIDEiQ5U0Q1

Expressioni

Gene expression databases

BgeeiENSG00000145907
ExpressionAtlasiQ5U0Q1 baseline and differential

Structurei

3D structure databases

SMRiQ5U0Q1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 133NTF2InterPro annotationAdd BLAST123
Domaini340 – 415RRMInterPro annotationAdd BLAST76

Phylogenomic databases

eggNOGiKOG0116 Eukaryota
ENOG410YV57 LUCA
HOVERGENiHBG007211
KOiK17265
OMAiACAFLEF
OrthoDBiEOG091G0GAN

Family and domain databases

CDDicd00780 NTF2, 1 hit
cd12463 RRM_G3BP1, 1 hit
InterProiView protein in InterPro
IPR034375 G3BP1
IPR034374 G3BP1_RRM
IPR002075 NTF2
IPR032710 NTF2-like_dom_sf
IPR018222 Nuclear_transport_factor_2_euk
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PANTHERiPTHR10693:SF21 PTHR10693:SF21, 1 hit
PfamiView protein in Pfam
PF02136 NTF2, 1 hit
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit
SSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50177 NTF2_DOMAIN, 1 hit
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Complete.

Q5U0Q1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVMEKPSPLL VGREFVRQYY TLLNQAPDML HRFYGKNSSY VHGGLDSNGK
60 70 80 90 100
PADAVYGQKE IHRKVMSQNF TNCHTKIRHV DAHATLNDGV VVQVMGLLSN
110 120 130 140 150
NNQALRRFMQ TFVLAPEGSV ANKFYVHNDI FRYQDEVFGG FVTEPQEESE
160 170 180 190 200
EEVEEPEERQ QTPEVVPDDS GTFYDQAVVS NDMEEHLEEP VAEPEPDPEP
210 220 230 240 250
EPEQEPVSEI QEEKPEPVLE ETAPEDAQKS SSPAPADIAQ TVQEDLRTFS
260 270 280 290 300
WASVTSKNLP PSGAVPVTGI PPHVVKVPAS QPRPESKPES QIPPQRPQRD
310 320 330 340 350
QRVREQRINI PPQRGPRPIR EAGEQGDIEP RRMVRHPDSH QLFIGNLPHE
360 370 380 390 400
VDKSELKDFF QSYGNVVELR INSGGKLPNF GFVVFDDSEP VQKVLSNRPI
410 420 430 440 450
MFRGEVRLNV EEKKTRAARE GDRRDNRLRG PGGPRGGLGG GMRGPPRGGM
460
VQKPGFGVGR GLAPRQ
Length:466
Mass (Da):52,164
Last modified:May 10, 2005 - v1
Checksum:i0F9429D78E0C7F59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019384 mRNA Translation: AAV38191.1
AK312572 mRNA Translation: BAG35467.1
BX648012 mRNA Translation: CAI46067.1
CH471062 Genomic DNA Translation: EAW61659.1
CH471062 Genomic DNA Translation: EAW61660.1
RefSeqiNP_005745.1, NM_005754.2
NP_938405.1, NM_198395.1
XP_006714812.1, XM_006714749.3
XP_006714813.1, XM_006714750.3
XP_016864411.1, XM_017008922.1
XP_016864412.1, XM_017008923.1
UniGeneiHs.3353
Hs.587054

Genome annotation databases

GeneIDi10146
KEGGihsa:10146
UCSCiuc003lum.4 human

Similar proteinsi

Entry informationi

Entry nameiQ5U0Q1_HUMAN
AccessioniPrimary (citable) accession number: Q5U0Q1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 20, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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