Q5U0P5 (Q5U0P5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Myogenic factor 5 EMBL AAV38206.1
Organism	Homo sapiens (Human) EMBL AAV38206.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subunit structure	Efficient DNA binding requires dimerization with another bHLH protein By similarity. RuleBase RU003428
Sequence similarities	Contains 1 basic helix-loop-helix (bHLH) domain. RuleBase RU003428

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU003428
Ligand	DNA-binding RuleBase RU003428
Gene Ontology (GO)
Biological_process	muscle organ development Inferred from electronic annotation. Source: InterPro regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5U0P5 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: E5D5D773E2FC6770	FASTA	255	28,344
	10 20 30 40 50 60 MDVMDGCQFS PSEYFYDGSC IPSPEGEFGD EFVPRVAAFG AHKAELQGSY EDEHVRAPTG 70 80 90 100 110 120 HHQAGHCLMW ACKACKRKST TMDRRKAATM RERRRLKKVN QAFETLKRCT TTNPNQRLPK 130 140 150 160 170 180 VEILRNAIRY IESLQELLRE QVENYYSLPG QSCSEPTSPT SNCSDGMPEC NSPVWSRKSS 190 200 210 220 230 240 TFDSIYCPDV SNVYATDKNS LSSLDCLSNI VDRITSSEQP GLPLQDLASL SPVASTDSQP 250 ATPGASSSRL IYHVL

References

[1]	"Cloning of human full-length CDSs in BD Creator(TM) System Donor vector." Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BT019399 mRNA. Translation: AAV38206.1.
IPI	IPI00008389.
UniGene	Hs.178023.
3D structure databases
ProteinModelPortal	Q5U0P5.
SMR	Q5U0P5. Positions 76-140.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG006429.
Family and domain databases
Gene3D	4.10.280.10. 1 hit.
InterPro	IPR002546. Basic. IPR011598. bHLH_dom. IPR022032. Myf5. [Graphical view]
Pfam	PF01586. Basic. 1 hit. PF00010. HLH. 1 hit. PF12232. Myf5. 1 hit. [Graphical view]
SMART	SM00520. BASIC. 1 hit. SM00353. HLH. 1 hit. [Graphical view]
SUPFAM	SSF47459. HLH_basic. 1 hit.
PROSITE	PS50888. BHLH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5U0P5_HUMAN

Accession

Primary (citable) accession number: Q5U0P5

Entry history

Integrated into UniProtKB/TrEMBL:	December 7, 2004
Last sequence update:	December 7, 2004
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.