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Protein
Submitted name:

cAMP responsive element binding protein 1

Gene

CREB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
cAMP responsive element binding protein 1Imported
Submitted name:
cAMP responsive element binding protein 1, isoform CRA_aImported
Submitted name:
cDNA, FLJ93156, Homo sapiens cAMP responsive element binding protein 1 (CREB1),transcript variant B, mRNAImported
Gene namesi
Name:CREB1Imported
ORF Names:hCG_15208Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000118260.14.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26864.

PTM / Processingi

Proteomic databases

MaxQBiQ5U0J5.

Expressioni

Gene expression databases

BgeeiENSG00000118260.
ExpressionAtlasiQ5U0J5. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ5U0J5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 160KIDInterPro annotationAdd BLAST60
Domaini283 – 334BZIPInterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili301 – 335Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3584. Eukaryota.
ENOG410ZZJZ. LUCA.
HOVERGENiHBG011077.
KOiK05870.
OMAiQXISTIA.
OrthoDBiEOG091G0FTJ.

Family and domain databases

InterProiView protein in InterPro
IPR004827. bZIP.
IPR003102. Coactivator_CBP_pKID.
IPR001630. Leuzip_CREB.
PfamiView protein in Pfam
PF00170. bZIP_1. 1 hit.
PF02173. pKID. 1 hit.
PRINTSiPR00041. LEUZIPPRCREB.
SMARTiView protein in SMART
SM00338. BRLZ. 1 hit.
PROSITEiView protein in PROSITE
PS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
PS50953. KID. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5U0J5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMESGAENQ QSGDAAVTEA ENQQMTVQAQ PQIATLAQVS MPAAHATSSA
60 70 80 90 100
PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQSSC KDLKRLFSGT
110 120 130 140 150
QISTIAESED SQESVDSVTD SQKRREILSR RPSYRKILND LSSDAPGVPR
160 170 180 190 200
IEEEKSEEET SAPAITTVTV PTPIYQTSSG QYIAITQGGA IQLANNGTDG
210 220 230 240 250
VQGLQTLTMT NAAATQPGTT ILQYAQTTDG QQILVPSNQV VVQAASGDVQ
260 270 280 290 300
TYQIRTAPTS TIAPGVVMAS SPALPTQPAE EAARKREVRL MKNREAAREC
310 320 330 340
RRKKKEYVKC LENRVAVLEN QNKTLIEELK ALKDLYCHKS D
Length:341
Mass (Da):36,688
Last modified:May 10, 2005 - v1
Checksum:iD5E989AE40BF69AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019509 mRNA. Translation: AAV38316.1.
AK312747 mRNA. Translation: BAG35615.1.
CH471063 Genomic DNA. Translation: EAW70405.1.
CH471063 Genomic DNA. Translation: EAW70410.1.
RefSeqiNP_604391.1. NM_134442.4.
XP_011508947.1. XM_011510645.1.
UniGeneiHs.516646.
Hs.717136.

Genome annotation databases

GeneIDi1385.
KEGGihsa:1385.
UCSCiuc002vcc.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ5U0J5_HUMAN
AccessioniPrimary (citable) accession number: Q5U0J5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 27, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.