Q5U0E6 (Q5U0E6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Serine/threonine kinase 24 (STE20 homolog, yeast) EMBL AAV38425.1

Submitted name:
Serine/threonine kinase 24 (STE20 homolog, yeast), isoform CRA_c EMBL EAX08987.1

Gene names

Name:	STK24 EMBL CAI13115.1
ORF Names:	hCG_27759 EMBL EAX08987.1, RP11-111L24.5-001 EMBL CAI13115.1

Organism

Homo sapiens (Human) EMBL AAV38425.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	431 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Molecular function	Kinase EMBL AAV38425.1 Transferase
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5U0E6 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 26D863FDFEDF90AD	FASTA	431	47,913
	10 20 30 40 50 60 MAHSPVQSGL PGMQNLKADP EELFTKLEKI GKGSFGEVFK GIDNRTQKVV AIKIIDLEEA 70 80 90 100 110 120 EDEIEDIQQE ITVLSQCDSP YVTKYYGSYL KDTKLWIIME YLGGGSALDL LEPGPLDETQ 130 140 150 160 170 180 IATILREILK GLDYLHSEKK IHRDIKAANV LLSEHGEVKL ADFGVAGQLT DTQIKRNTFV 190 200 210 220 230 240 GTPFWMAPEV IKQSAYDSKA DIWSLGITAI ELARGEPPHS ELHPMKVLFL IPKNNPPTLE 250 260 270 280 290 300 GNYSKPLKEF VEACLNKEPS FRPTAKELLK HKFILRNAKK TSYLTELIDR YKRWKAEQSH 310 320 330 340 350 360 DDSSSEDSDA ETDGQASGGS DSGDWIFTIR EKDPKNLENG ALQPSDLDRN KMKDIPKRPF 370 380 390 400 410 420 SQCLSTIISP LFAELKEKSQ ACGGNLGSIE ELRGAIYLAE EACPGISDTM VAQLVQRLQR 430 YSLSGGGTSS H

References

[1]	Pelan S. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Garner P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Cloning of human full-length CDSs in BD Creator(TM) System Donor vector." Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BT019619 mRNA. Translation: AAV38425.1. AL356423, AL137249 Genomic DNA. Translation: CAI13115.1. AL137249, AL356423 Genomic DNA. Translation: CAI39457.1. CH471085 Genomic DNA. Translation: EAX08987.1.
IPI	IPI00981772.
RefSeq	NP_001027467.2. NM_001032296.2.
UniGene	Hs.508514. Hs.713712.
3D structure databases
ProteinModelPortal	Q5U0E6.
SMR	Q5U0E6. Positions 13-299.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5U0E6.
Proteomic databases
PRIDE	Q5U0E6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8428.
KEGG	hsa:8428.
Organism-specific databases
CTD	8428.
PharmGKB	PA36210.
Phylogenomic databases
HOVERGEN	HBG108518.
Gene expression databases
ArrayExpress	Q5U0E6.
Bgee	Q5U0E6.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_kinase-like_dom. IPR002290. Ser/Thr_kinase_dom. [Graphical view]
KO	K08838.
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	31540.
PMAP-CutDB	Q5U0E6.

Entry information

Entry name

Q5U0E6_HUMAN

Accession

Primary (citable) accession number: Q5U0E6

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	November 16, 2011
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.