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Protein

Transgelin

Gene

TAGLN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
TransgelinUniRule annotation
Gene namesi
Name:TAGLNImported
Synonyms:DKFZp686P11128Imported
ORF Names:hCG_2032895Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA36324.

PTM / Processingi

Proteomic databases

MaxQBiQ5U0D2.

Expressioni

Gene expression databases

BgeeiENSG00000149591.
ExpressionAtlasiQ5U0D2. baseline and differential.

Interactioni

Protein-protein interaction databases

MINTiMINT-5003147.
STRINGi9606.ENSP00000278968.

Structurei

3D structure databases

SMRiQ5U0D2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 137Actin-bindingInterPro annotationAdd BLAST114

Sequence similaritiesi

Belongs to the calponin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2046. Eukaryota.
COG5199. LUCA.
HOVERGENiHBG005186.
KOiK20526.
OMAiVEWIVVQ.
OrthoDBiEOG091G0LY2.

Family and domain databases

CDDicd00014. CH. 1 hit.
Gene3Di1.10.418.10. 1 hit.
InterProiView protein in InterPro
IPR000557. Calponin_repeat.
IPR001715. CH-domain.
IPR003096. SM22_calponin.
IPR029976. TAGLN.
PANTHERiPTHR18959:SF65. PTHR18959:SF65. 1 hit.
PfamiView protein in Pfam
PF00402. Calponin. 1 hit.
PF00307. CH. 1 hit.
PRINTSiPR00888. SM22CALPONIN.
SMARTiView protein in SMART
SM00033. CH. 1 hit.
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiView protein in PROSITE
PS01052. CALPONIN_1. 1 hit.
PS51122. CALPONIN_2. 1 hit.
PS50021. CH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5U0D2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANKGPSYGM SREVQSKIEK KYDEELEERL VEWIIVQCGP DVGRPDRGRL
60 70 80 90 100
GFQVWLKNGV ILSKLVNSLY PDGSKPVKVP ENPPSMVFKQ MEQVAQFLKA
110 120 130 140 150
AEDYGVIKTD MFQTVDLFEG KDMAAVQRTL MALGSLAVTK NDGHYRGDPN
160 170 180 190 200
WFMKKAQEHK REFTESQLQE GKHVIGLQMG SNRGASQAGM TGYGRPRQII

S
Length:201
Mass (Da):22,611
Last modified:May 10, 2005 - v1
Checksum:i7AE9E7A9A45602C3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei201Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC092415 mRNA. Translation: AAH92415.1.
BC093050 mRNA. Translation: AAH93050.1.
BT019648 mRNA. Translation: AAV38454.1.
BT019649 mRNA. Translation: AAV38455.1.
EF445034 Genomic DNA. Translation: ACA06080.1.
AK314043 mRNA. Translation: BAG36752.1.
CR541681 mRNA. Translation: CAG46482.1.
CR749612 mRNA. Translation: CAH18406.1.
CH471065 Genomic DNA. Translation: EAW67299.1.
CH471065 Genomic DNA. Translation: EAW67301.1.
RefSeqiNP_001001522.1. NM_001001522.1.
NP_003177.2. NM_003186.3.
UniGeneiHs.410977.

Genome annotation databases

GeneIDi6876.
KEGGihsa:6876.
UCSCiuc001pqm.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC092415 mRNA. Translation: AAH92415.1.
BC093050 mRNA. Translation: AAH93050.1.
BT019648 mRNA. Translation: AAV38454.1.
BT019649 mRNA. Translation: AAV38455.1.
EF445034 Genomic DNA. Translation: ACA06080.1.
AK314043 mRNA. Translation: BAG36752.1.
CR541681 mRNA. Translation: CAG46482.1.
CR749612 mRNA. Translation: CAH18406.1.
CH471065 Genomic DNA. Translation: EAW67299.1.
CH471065 Genomic DNA. Translation: EAW67301.1.
RefSeqiNP_001001522.1. NM_001001522.1.
NP_003177.2. NM_003186.3.
UniGeneiHs.410977.

3D structure databases

SMRiQ5U0D2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-5003147.
STRINGi9606.ENSP00000278968.

Proteomic databases

MaxQBiQ5U0D2.

Protocols and materials databases

DNASUi6876.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6876.
KEGGihsa:6876.
UCSCiuc001pqm.4. human.

Organism-specific databases

CTDi6876.
PharmGKBiPA36324.

Phylogenomic databases

eggNOGiKOG2046. Eukaryota.
COG5199. LUCA.
HOVERGENiHBG005186.
KOiK20526.
OMAiVEWIVVQ.
OrthoDBiEOG091G0LY2.

Miscellaneous databases

ChiTaRSiTAGLN. human.
GenomeRNAii6876.

Gene expression databases

BgeeiENSG00000149591.
ExpressionAtlasiQ5U0D2. baseline and differential.

Family and domain databases

CDDicd00014. CH. 1 hit.
Gene3Di1.10.418.10. 1 hit.
InterProiView protein in InterPro
IPR000557. Calponin_repeat.
IPR001715. CH-domain.
IPR003096. SM22_calponin.
IPR029976. TAGLN.
PANTHERiPTHR18959:SF65. PTHR18959:SF65. 1 hit.
PfamiView protein in Pfam
PF00402. Calponin. 1 hit.
PF00307. CH. 1 hit.
PRINTSiPR00888. SM22CALPONIN.
SMARTiView protein in SMART
SM00033. CH. 1 hit.
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiView protein in PROSITE
PS01052. CALPONIN_1. 1 hit.
PS51122. CALPONIN_2. 1 hit.
PS50021. CH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5U0D2_HUMAN
AccessioniPrimary (citable) accession number: Q5U0D2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: March 15, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.