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Unreviewed, UniProtKB/TrEMBL Q5U091 (Q5U091_HUMAN)

Last modified February 9, 2010. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Neuroblastoma RAS viral (V-ras) oncogene homolog EMBL AAV38540.1
Submitted name:
    Neuroblastoma RAS viral (V-ras) oncogene homolog, isoform CRA_a EMBL EAW56608.1
Gene names
Name: NRAS EMBL EAW56608.1
ORF Names: RP5-1000E10.2-001 EMBL CAI18827.1, hCG_38454 EMBL EAW56608.1
OrganismHomo sapiens (Human) EMBL AAV38540.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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Ontologies

Keywords
   LigandGTP-binding RuleBase RU003312V0 Spearmint SPM003577
Nucleotide-binding
Gene Ontology (GO)
   Biological processactin cytoskeleton organization

Inferred from electronic annotation. Source: Compara

cell aging

Inferred from electronic annotation. Source: Compara

endocytosis

Inferred from electronic annotation. Source: Compara

negative regulation of neuron apoptosis

Inferred from electronic annotation. Source: Compara

positive regulation of Rac protein signal transduction

Inferred from electronic annotation. Source: Compara

positive regulation of cell proliferation

Inferred from electronic annotation. Source: Compara

regulation of long-term neuronal synaptic plasticity

Inferred from electronic annotation. Source: Compara

regulation of synaptic transmission, GABAergic

Inferred from electronic annotation. Source: Compara

small GTPase mediated signal transduction

Inferred from electronic annotation. Source: InterPro

striated muscle cell differentiation

Inferred from electronic annotation. Source: Compara

visual learning

Inferred from electronic annotation. Source: Compara

   Cellular componentintracellular

Inferred from electronic annotation. Source: InterPro

membrane

Inferred from electronic annotation. Source: InterPro

membrane fraction

Inferred from electronic annotation. Source: Compara

   Molecular functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-KW

GTPase activity

Inferred from electronic annotation. Source: InterPro

protein binding

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

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Sequences

Sequence LengthMass (Da)Tools
Q5U091-1 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 6898D3F6815B1EC7

FASTA18921,229
        10         20         30         40         50         60 
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG 

        70         80         90        100        110        120 
QEEYSAMRDQ YMRTGEGFLC VFAINNSKSF ADINLYREQI KRVKDSDDVP MVLVGNKCDL 

       130        140        150        160        170        180 
PTRTVDTKQA HELAKSYGIP FIETSAKTRQ GVEDAFYTLV REIRQYRMKK LNSSDDGTQG 


CMGLPCVVM

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References

[1]"Cloning of human full-length CDSs in BD Creator(TM) System Donor vector."
Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[2]Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[3]Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O., Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[4]Grafham D.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BT019734 mRNA. Translation: AAV38539.1.
BT019735 mRNA. Translation: AAV38540.1.
EU332857 Genomic DNA. Translation: ABY87546.1.
AL096773 Genomic DNA. Translation: CAI18827.1.
CH471122 Genomic DNA. Translation: EAW56608.1.
IPIIPI00000005.
RefSeqNP_002515.1.
UniGeneHs.486502

3D structure databases

SMRQ5U091. Positions 1-166.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5U091.

Proteomic databases

PRIDEQ5U091.

Genome annotation databases

EnsemblENST00000369535; ENSP00000358548; ENSG00000213281; Homo sapiens. [Genome view]
GeneID4893.
KEGGhsa:4893.

Organism-specific databases

CTD4893.
HGNCHGNC:7989. NRAS.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ5U091.
OMAEDGNQGC.
PhylomeDBQ5U091.

Gene expression databases

ArrayExpressQ5U091.
BgeeQ5U091.

Family and domain databases

InterProIPR003577. GTPase_Ras.
IPR013753. Ras.
IPR001806. Ras_GTPase.
IPR015592. Ras_Ras_related.
IPR020849. Ras_small_GTPase.
IPR005225. Small_GTP_bd.
[Graphical view]
PANTHERPTHR11708:SF125. Ras_Ras_related. 1 hit.
PfamPF00071. Ras. 1 hit.
[Graphical view]
PRINTSPR00449. RASTRNSFRMNG.
SMARTSM00173. RAS. 1 hit.
[Graphical view]
TIGRFAMsTIGR00231. small_GTP. 1 hit.
PROSITEPS51421. RAS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio18835.

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Entry information

Entry nameQ5U091_HUMAN
AccessionPrimary (citable) accession number: Q5U091
Entry history
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: February 9, 2010
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information