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Protein
Submitted name:

Neuroblastoma RAS viral (V-ras) oncogene homolog

Gene

NRAS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Neuroblastoma RAS viral (V-ras) oncogene homologImported
Submitted name:
Neuroblastoma RAS viral (V-ras) oncogene homolog, isoform CRA_aImported
Gene namesi
Name:NRASImported
ORF Names:hCG_38454Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31768.

PTM / Processingi

Proteomic databases

MaxQBiQ5U091.

Expressioni

Gene expression databases

BgeeiENSG00000213281.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000358548.

Structurei

3D structure databases

SMRiQ5U091. Positions 1-167.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0395. Eukaryota.
COG1100. LUCA.
HOVERGENiHBG009351.
KOiK07828.
OMAiRSSYDEI.
OrthoDBiEOG091G0UAU.
PhylomeDBiQ5U091.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR020849. Small_GTPase_Ras.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51421. RAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5U091-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET
60 70 80 90 100
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNSKSF ADINLYREQI
110 120 130 140 150
KRVKDSDDVP MVLVGNKCDL PTRTVDTKQA HELAKSYGIP FIETSAKTRQ
160 170 180
GVEDAFYTLV REIRQYRMKK LNSSDDGTQG CMGLPCVVM
Length:189
Mass (Da):21,229
Last modified:May 10, 2005 - v1
Checksum:i6898D3F6815B1EC7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019734 mRNA. Translation: AAV38539.1.
BT019735 mRNA. Translation: AAV38540.1.
EU332857 Genomic DNA. Translation: ABY87546.1.
CH471122 Genomic DNA. Translation: EAW56608.1.
CH471122 Genomic DNA. Translation: EAW56609.1.
CH471122 Genomic DNA. Translation: EAW56610.1.
CH471122 Genomic DNA. Translation: EAW56611.1.
RefSeqiNP_002515.1. NM_002524.4.
UniGeneiHs.486502.

Genome annotation databases

GeneIDi4893.
KEGGihsa:4893.
UCSCiuc009wgu.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019734 mRNA. Translation: AAV38539.1.
BT019735 mRNA. Translation: AAV38540.1.
EU332857 Genomic DNA. Translation: ABY87546.1.
CH471122 Genomic DNA. Translation: EAW56608.1.
CH471122 Genomic DNA. Translation: EAW56609.1.
CH471122 Genomic DNA. Translation: EAW56610.1.
CH471122 Genomic DNA. Translation: EAW56611.1.
RefSeqiNP_002515.1. NM_002524.4.
UniGeneiHs.486502.

3D structure databases

SMRiQ5U091. Positions 1-167.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000358548.

Proteomic databases

MaxQBiQ5U091.

Protocols and materials databases

DNASUi4893.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4893.
KEGGihsa:4893.
UCSCiuc009wgu.4. human.

Organism-specific databases

CTDi4893.
PharmGKBiPA31768.

Phylogenomic databases

eggNOGiKOG0395. Eukaryota.
COG1100. LUCA.
HOVERGENiHBG009351.
KOiK07828.
OMAiRSSYDEI.
OrthoDBiEOG091G0UAU.
PhylomeDBiQ5U091.

Miscellaneous databases

ChiTaRSiNRAS. human.
GenomeRNAii4893.

Gene expression databases

BgeeiENSG00000213281.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR020849. Small_GTPase_Ras.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51421. RAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5U091_HUMAN
AccessioniPrimary (citable) accession number: Q5U091
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.