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Protein
Submitted name:

Growth associated protein 43

Gene

GAP43

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Growth associated protein 43Imported
Submitted name:
cDNA, FLJ94238, Homo sapiens growth associated protein 43 (GAP43), mRNAImported
Gene namesi
Name:GAP43Imported
ORF Names:hCG_2022854Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000172020.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28553

PTM / Processingi

Proteomic databases

MaxQBiQ5U058

Expressioni

Gene expression databases

BgeeiENSG00000172020
ExpressionAtlasiQ5U058 baseline and differential

Structurei

3D structure databases

SMRiQ5U058
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 31Neuromodulin_NInterPro annotationAdd BLAST30
Domaini67 – 238NeuromodulinInterPro annotationAdd BLAST172

Phylogenomic databases

eggNOGiENOG410IVZP Eukaryota
ENOG411256P LUCA
HOVERGENiHBG006468
KOiK20041

Family and domain databases

InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR001422 Neuromodulin
IPR017454 Neuromodulin_C
IPR018947 Neuromodulin_gap-junction_N
IPR033137 Neuromodulin_P_site
IPR018243 Neuromodulin_palmitoyl_site
PfamiView protein in Pfam
PF00612 IQ, 1 hit
PF06614 Neuromodulin, 1 hit
PF10580 Neuromodulin_N, 1 hit
PRINTSiPR00215 NEUROMODULIN
SMARTiView protein in SMART
SM00015 IQ, 1 hit
PROSITEiView protein in PROSITE
PS50096 IQ, 1 hit
PS00412 NEUROMODULIN_1, 1 hit
PS00413 NEUROMODULIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5U058-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLCCMRRTKQ VEKNDDDQKI EQDGIKPEDK AHKAATKIQA SFRGHITRKK
60 70 80 90 100
LKGEKKDDVQ AAEAEANKKD EAPVADGVEK KGEGTTTAEA APATGSKPDE
110 120 130 140 150
PGKAGETPSE EKKGEGDAAT EQAAPQAPAS SEEKAGSAET ESATKASTDN
160 170 180 190 200
SPSSKAEDAP AKEEPKQADV PAAVTAAAAT TPAAEDAAAK ATAQPPTETG
210 220 230
ESSQAEENIE AVDETKPKES ARQDEGKEEE PEADQEHA
Length:238
Mass (Da):24,803
Last modified:May 10, 2005 - v1
Checksum:iB3536D012A127CC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019771 mRNA Translation: AAV38576.1
BT019810 mRNA Translation: AAV38613.1
AK313658 mRNA Translation: BAG36412.1
CH471052 Genomic DNA Translation: EAW79594.1
RefSeqiNP_002036.1, NM_002045.3
UniGeneiHs.134974

Genome annotation databases

GeneIDi2596
KEGGihsa:2596
UCSCiuc003ebq.3 human

Similar proteinsi

Entry informationi

Entry nameiQ5U058_HUMAN
AccessioniPrimary (citable) accession number: Q5U058
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health