Unreviewed, UniProtKB/TrEMBL Q5U045 (Q5U045_HUMAN)

Names and origin

Protein names

Submitted name:
    Casein kinase 1 epsilon EMBL ABM64212.1
Submitted name:
    Casein kinase 1, epsilon EMBL AAV38634.1
    HCG2014051, isoform CRA_a EMBL EAW60228.1

Gene names

Name:	CSNK1E EMBL ABM64212.1
ORF Names:	hCG_2014051 EMBL EAW60228.1

Organism

Homo sapiens (Human) EMBL AAV38634.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	416 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the protein kinase superfamily.

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304V2 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305V3 Transferase
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5U045-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: EE1B1698AE914324	FASTA	416	47,315
	10 20 30 40 50 60 MELRVGNKYR LGRKIGSGSF GDIYLGANIA SGEEVAIKLE CVKTKHPQLH IESKFYKMMQ 70 80 90 100 110 120 GGVGIPSIKW CGAEGDYNVM VMELLGPSLE DLFNFCSRKF SLKTVLLLAD QMISRIEYIH 130 140 150 160 170 180 SKNFIHRDVK PDNFLMGLGK KGNLVYIIDF GLAKKYRDAR THQHIPYREN KNLTGTARYA 190 200 210 220 230 240 SINTHLGIEQ SRRDDLESLG YVLMYFNLGS LPWQGLKAAT KRQKYERISE KKMSTPIEVL 250 260 270 280 290 300 CKGYPSEFST YLNFCRSLRF DDKPDYSYLR QLFRNLFHRQ GFSYDYVFDW NMLKFGAARN 310 320 330 340 350 360 PEDVDRERRE HEREERMGQL RGSATRALPP GPPTGATANR LRSAAEPVAS TPASRIQPAG 370 380 390 400 410 NTSPRAISRV DRERKVSMRL HRGAPANVSS SDLTGRQEVS RIPASQTSVP FDHLGK

References

[1]	"Cloning of human full-length CDSs in BD Creator(TM) System Donor vector." Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"CSNK1E Resequence." Kripke D.F., Klimecki W. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BT019831 mRNA. Translation: AAV38634.1. EF015901 Genomic DNA. Translation: ABM64212.1. CH471095 Genomic DNA. Translation: EAW60228.1.
IPI	IPI00027729.
RefSeq	NP_001885.1. NP_689407.1.
UniGene	Hs.474833
3D structure databases
SMR	Q5U045. Positions 1-296.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5U045.
Proteomic databases
PRIDE	Q5U045.
Genome annotation databases
Ensembl	ENST00000359867; ENSP00000352929; ENSG00000213923; Homo sapiens. [Genome view] ENST00000396832; ENSP00000380044; ENSG00000213923; Homo sapiens. [Genome view] ENST00000400206; ENSP00000383067; ENSG00000213923; Homo sapiens. [Genome view] ENST00000402865; ENSP00000385582; ENSG00000213923; Homo sapiens. [Genome view] ENST00000403904; ENSP00000384074; ENSG00000213923; Homo sapiens. [Genome view] ENST00000438038; ENSP00000387440; ENSG00000213923; Homo sapiens. [Genome view]
GeneID	1454.
KEGG	hsa:1454.
Organism-specific databases
CTD	1454.
HGNC	HGNC:2453. CSNK1E.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q5U045.
PhylomeDB	Q5U045.
Gene expression databases
ArrayExpress	Q5U045.
Bgee	Q5U045.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	5969.

Entry information

Entry name

Q5U045_HUMAN

Accession

Primary (citable) accession number: Q5U045

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	February 9, 2010
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.