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Protein
Submitted name:

Chemokine (C-C motif) receptor 1

Gene

CCR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Chemokine (C-C motif) receptor 1Imported
Submitted name:
Chemokine (C-C motif) receptor 1, isoform CRA_aImported
Gene namesi
Name:CCR1Imported
ORF Names:hCG_15324Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei40 – 6021HelicalSequence analysisAdd
BLAST
Transmembranei72 – 9120HelicalSequence analysisAdd
BLAST
Transmembranei111 – 13424HelicalSequence analysisAdd
BLAST
Transmembranei146 – 17025HelicalSequence analysisAdd
BLAST
Transmembranei205 – 22723HelicalSequence analysisAdd
BLAST
Transmembranei239 – 26123HelicalSequence analysisAdd
BLAST
Transmembranei281 – 30424HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26166.

Expressioni

Gene expression databases

BgeeiENSG00000163823.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000296140.

Structurei

3D structure databases

SMRiQ5U003. Positions 2-317.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini51 – 301251G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106917.
KOiK04176.
OMAiFWIDYKL.
OrthoDBiEOG091G0B7A.
PhylomeDBiQ5U003.

Family and domain databases

InterProiIPR002236. Chemokine_CCR1.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR10489:SF711. PTHR10489:SF711. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR01106. CHEMOKINER1.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5U003-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METPNTTEDY DTTTEFDYGD ATPCQKVNER AFGAQLLPPL YSLVFVIGLV
60 70 80 90 100
GNILVVLVLV QYKRLKNMTS IYLLNLAISD LLFLFTLPFW IDYKLKDDWV
110 120 130 140 150
FGDAMCKILS GFYYTGLYSE IFFIILLTID RYLAIVHAVF ALRARTVTFG
160 170 180 190 200
VITSIIIWAL AILASMPGLY FSKTQWEFTH HTCSLHFPHE SLREWKLFQA
210 220 230 240 250
LKLNLFGLVL PLLVMIICYT GIIKILLRRP NEKKSKAVRL IFVIMIIFFL
260 270 280 290 300
FWTPYNLTIL ISVFQDFLFT HECEQSRHLD LAVQVTEVIA YTHCCVNPVI
310 320 330 340 350
YAFVGERFRK YLRQLFHRRV AVHLVKWLPF LSVDRLERVS STSPSTGEHE

LSAGF
Length:355
Mass (Da):41,173
Last modified:May 10, 2005 - v1
Checksum:iB2C100FFED275985
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019908 mRNA. Translation: AAV38711.1.
BT019909 mRNA. Translation: AAV38712.1.
CH471055 Genomic DNA. Translation: EAW64756.1.
CH471055 Genomic DNA. Translation: EAW64757.1.
RefSeqiNP_001286.1. NM_001295.2.
UniGeneiHs.301921.

Genome annotation databases

GeneIDi1230.
KEGGihsa:1230.
UCSCiuc003cph.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019908 mRNA. Translation: AAV38711.1.
BT019909 mRNA. Translation: AAV38712.1.
CH471055 Genomic DNA. Translation: EAW64756.1.
CH471055 Genomic DNA. Translation: EAW64757.1.
RefSeqiNP_001286.1. NM_001295.2.
UniGeneiHs.301921.

3D structure databases

SMRiQ5U003. Positions 2-317.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000296140.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

DNASUi1230.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1230.
KEGGihsa:1230.
UCSCiuc003cph.2. human.

Organism-specific databases

CTDi1230.
PharmGKBiPA26166.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106917.
KOiK04176.
OMAiFWIDYKL.
OrthoDBiEOG091G0B7A.
PhylomeDBiQ5U003.

Miscellaneous databases

GenomeRNAii1230.

Gene expression databases

BgeeiENSG00000163823.

Family and domain databases

InterProiIPR002236. Chemokine_CCR1.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR10489:SF711. PTHR10489:SF711. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR01106. CHEMOKINER1.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5U003_HUMAN
AccessioniPrimary (citable) accession number: Q5U003
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.