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Protein
Submitted name:

Chemokine (C-C motif) receptor 1

Gene

CCR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Chemokine (C-C motif) receptor 1Imported
Submitted name:
Chemokine (C-C motif) receptor 1, isoform CRA_aImported
Gene namesi
Name:CCR1Imported
ORF Names:hCG_15324Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000163823.3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Transmembranei72 – 91HelicalSequence analysisAdd BLAST20
Transmembranei111 – 134HelicalSequence analysisAdd BLAST24
Transmembranei146 – 170HelicalSequence analysisAdd BLAST25
Transmembranei205 – 227HelicalSequence analysisAdd BLAST23
Transmembranei239 – 261HelicalSequence analysisAdd BLAST23
Transmembranei281 – 304HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26166.

Expressioni

Gene expression databases

BgeeiENSG00000163823.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 301G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST251

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106917.
KOiK04176.
OMAiLHFPHES.
OrthoDBiEOG091G0B7A.

Family and domain databases

InterProiView protein in InterPro
IPR002236. Chemokine_CCR1.
IPR034321. Chemokine_CCR1_euk.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PANTHERiPTHR10489:SF711. PTHR10489:SF711. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00657. CCCHEMOKINER.
PR01106. CHEMOKINER1.
PR00237. GPCRRHODOPSN.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5U003-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METPNTTEDY DTTTEFDYGD ATPCQKVNER AFGAQLLPPL YSLVFVIGLV
60 70 80 90 100
GNILVVLVLV QYKRLKNMTS IYLLNLAISD LLFLFTLPFW IDYKLKDDWV
110 120 130 140 150
FGDAMCKILS GFYYTGLYSE IFFIILLTID RYLAIVHAVF ALRARTVTFG
160 170 180 190 200
VITSIIIWAL AILASMPGLY FSKTQWEFTH HTCSLHFPHE SLREWKLFQA
210 220 230 240 250
LKLNLFGLVL PLLVMIICYT GIIKILLRRP NEKKSKAVRL IFVIMIIFFL
260 270 280 290 300
FWTPYNLTIL ISVFQDFLFT HECEQSRHLD LAVQVTEVIA YTHCCVNPVI
310 320 330 340 350
YAFVGERFRK YLRQLFHRRV AVHLVKWLPF LSVDRLERVS STSPSTGEHE

LSAGF
Length:355
Mass (Da):41,173
Last modified:May 10, 2005 - v1
Checksum:iB2C100FFED275985
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019908 mRNA. Translation: AAV38711.1.
BT019909 mRNA. Translation: AAV38712.1.
CH471055 Genomic DNA. Translation: EAW64756.1.
CH471055 Genomic DNA. Translation: EAW64757.1.
RefSeqiNP_001286.1. NM_001295.2.
UniGeneiHs.301921.

Genome annotation databases

GeneIDi1230.
KEGGihsa:1230.
UCSCiuc003cph.2. human.

Similar proteinsi

Entry informationi

Entry nameiQ5U003_HUMAN
AccessioniPrimary (citable) accession number: Q5U003
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: March 28, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.