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Protein
Submitted name:

UBE2C protein

Gene

UBE2C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathwayUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
UBE2C proteinImported
Submitted name:
Ubiquitin-conjugating enzyme E2CImported
Submitted name:
Ubiquitin-conjugating enzyme E2C, isoform CRA_eImported
Gene namesi
Name:UBE2CImported
ORF Names:hCG_38372Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38057.

PTM / Processingi

Proteomic databases

MaxQBiQ5TZN3.

Expressioni

Gene expression databases

BgeeiENSG00000175063.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000348838.

Structurei

3D structure databases

SMRiQ5TZN3. Positions 29-173.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini33 – 158126UBIQUITIN_CONJUGAT_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0421. Eukaryota.
ENOG4111IGV. LUCA.
HOVERGENiHBG063308.
KOiK06688.
OMAiELMQLMM.
OrthoDBiEOG091G0M7S.
PhylomeDBiQ5TZN3.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5TZN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI
60 70 80 90 100
SAFPESDNLF KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT
110 120 130 140 150
PCYHPNVDTQ GNICLDILKE KWSALYDVRT ILLSIQSLLG EPNIDSPLNT
160 170
HAAELWKNPT AFKKYLQETY SKQVTSQEP
Length:179
Mass (Da):19,652
Last modified:May 10, 2005 - v1
Checksum:i0B6F58A1F0665D9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT020165 mRNA. Translation: AAV38967.1.
BT020166 mRNA. Translation: AAV38968.1.
CR456988 mRNA. Translation: CAG33269.1.
CH471077 Genomic DNA. Translation: EAW75809.1.
RefSeqiNP_008950.1. NM_007019.3.
UniGeneiHs.93002.

Genome annotation databases

GeneIDi11065.
KEGGihsa:11065.
UCSCiuc002xpm.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT020165 mRNA. Translation: AAV38967.1.
BT020166 mRNA. Translation: AAV38968.1.
CR456988 mRNA. Translation: CAG33269.1.
CH471077 Genomic DNA. Translation: EAW75809.1.
RefSeqiNP_008950.1. NM_007019.3.
UniGeneiHs.93002.

3D structure databases

SMRiQ5TZN3. Positions 29-173.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000348838.

Proteomic databases

MaxQBiQ5TZN3.

Protocols and materials databases

DNASUi11065.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11065.
KEGGihsa:11065.
UCSCiuc002xpm.4. human.

Organism-specific databases

CTDi11065.
PharmGKBiPA38057.

Phylogenomic databases

eggNOGiKOG0421. Eukaryota.
ENOG4111IGV. LUCA.
HOVERGENiHBG063308.
KOiK06688.
OMAiELMQLMM.
OrthoDBiEOG091G0M7S.
PhylomeDBiQ5TZN3.

Miscellaneous databases

ChiTaRSiUBE2C. human.
GenomeRNAii11065.

Gene expression databases

BgeeiENSG00000175063.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5TZN3_HUMAN
AccessioniPrimary (citable) accession number: Q5TZN3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.