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Protein
Submitted name:

UBE2C protein

Gene

UBE2C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei114Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Biological processUbl conjugation pathwayUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
UBE2C proteinImported
Submitted name:
Ubiquitin-conjugating enzyme E2CImported
Submitted name:
Ubiquitin-conjugating enzyme E2C, isoform CRA_eImported
Gene namesi
Name:UBE2CImported
ORF Names:hCG_38372Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000175063.16.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38057.

PTM / Processingi

Proteomic databases

MaxQBiQ5TZN3.

Expressioni

Gene expression databases

BgeeiENSG00000175063.

Interactioni

Protein-protein interaction databases

IntActiQ5TZN3. 3 interactors.

Structurei

3D structure databases

SMRiQ5TZN3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 158UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0421. Eukaryota.
ENOG4111IGV. LUCA.
HOVERGENiHBG063308.
KOiK06688.
OMAiAELWDKD.
OrthoDBiEOG091G0M7S.

Family and domain databases

CDDicd00195. UBCc. 1 hit.
Gene3Di3.10.110.10. 1 hit.
InterProiView protein in InterPro
IPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
PfamiView protein in Pfam
PF00179. UQ_con. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiView protein in PROSITE
PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5TZN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI
60 70 80 90 100
SAFPESDNLF KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT
110 120 130 140 150
PCYHPNVDTQ GNICLDILKE KWSALYDVRT ILLSIQSLLG EPNIDSPLNT
160 170
HAAELWKNPT AFKKYLQETY SKQVTSQEP
Length:179
Mass (Da):19,652
Last modified:May 10, 2005 - v1
Checksum:i0B6F58A1F0665D9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT020165 mRNA. Translation: AAV38967.1.
BT020166 mRNA. Translation: AAV38968.1.
CR456988 mRNA. Translation: CAG33269.1.
CH471077 Genomic DNA. Translation: EAW75809.1.
RefSeqiNP_008950.1. NM_007019.3.
UniGeneiHs.93002.

Genome annotation databases

GeneIDi11065.
KEGGihsa:11065.
UCSCiuc002xpm.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ5TZN3_HUMAN
AccessioniPrimary (citable) accession number: Q5TZN3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 22, 2017
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.